Genetic evolution of hemagglutinin and neuraminidase genes of H5N1 highly pathogenic avian influenza viruses in Thailand

• Published in: PeerJ Vol. 10; p. e14419
• Main Authors: Noisumdaeng, Pirom, Phadungsombat, Juthamas, Weerated, Sasrinakarn, Wiriyarat, Witthawat, Puthavathana, Pilaipan
• Format: Journal Article
• Language: English
• Published: United States PeerJ 30.11.2022; PeerJ. Ltd; PeerJ, Inc; PeerJ Inc
• Subjects: Analysis; Animals; Avian flu; Avian influenza; Avian influenza viruses; Bayes Theorem; Bayesian analysis; Bioinformatics; Biology (General); Birds; Epidemics; Epidemiology; Evolution; Evolution & development; Evolution, Molecular; Evolutionary genetics; Evolutionary Studies; Exo-a-sialidase; Fatalities; Genes; Genetic evolution; H5N1 highly pathogenic avian influenza (HPAI) virus; Hemagglutinin; Hemagglutinins; Influenza A virus; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H5N1 Subtype - genetics; Influenza in Birds; Influenza in Birds - epidemiology; Lectins; Markov chains; Markov processes; Medicine; Microbiology; Molecular Biology; Monte Carlo method; Neuraminidase; Neuraminidase - genetics; Phylogenetics; Phylogeny; Poultry; Public health; QH301-705.5; R; Reassortant H5Nx viruses; Thailand; Thailand - epidemiology; Virology; Viruses; Working groups; Thailand; Vietnam; Cambodia; Laos; China; Hong Kong; Asia; United States > US; Europe; North America; Antigua; H5N1 highly pathogenic avian influenza (HPAI) virus; Genetic evolution; Reassortant H5Nx viruses; Hemagglutinin; Neuraminidase

Ongoing outbreaks of H5N1 highly pathogenic avian influenza (HPAI) viruses and the emergence of the genetic-related hemagglutinin ( ) gene of reassortant H5Nx viruses currently circulating in wild birds and poultries pose a great global public health concern. In this study, we comprehensively analyz...