Neural Substrates Related to Motor Memory with Multiple Timescales in Sensorimotor Adaptation

• Published in: PLoS biology Vol. 13; no. 12; p. e1002312
• Main Authors: Kim, Sungshin, Ogawa, Kenji, Lv, Jinchi, Schweighofer, Nicolas, Imamizu, Hiroshi
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.12.2015; Public Library of Science (PLoS)
• Subjects: Adaptation; Adaptation, Physiological; Adult; Behavior; Brain Mapping; Cerebellar Nuclei; Data analysis; Experiments; Female; Fourier transforms; Functional Laterality; Humans; Kinetics; Magnetic Resonance Imaging; Male; Medical imaging; Memory, Long-Term; Memory, Short-Term; Middle Aged; Models, Neurological; Multivariate Analysis; Neurons - metabolism; NMR; Nuclear magnetic resonance; Parietal Lobe - metabolism; Psychomotor Performance; Sensorimotor Cortex - metabolism; Studies; Tomography; Variance analysis; Young Adult

Recent computational and behavioral studies suggest that motor adaptation results from the update of multiple memories with different timescales. Here, we designed a model-based functional magnetic resonance imaging (fMRI) experiment in which subjects adapted to two opposing visuomotor rotations. A...