DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression - Ning, Xianghong; Shi, Zhendong; Liu, Xi; Zhang, Anling; Han, Lei; Jiang, Kui; Kang, Chunsheng; Zhang, Qingyu (Cancer letters, 2015)
Keywords: Adenosine - analogs & derivatives; Adenosine - pharmacology; Animals; Antineoplastic Agents - pharmacology; Azacitidine - analogs & derivatives; Azacitidine - pharmacology; Cell Line, Tumor; Chromatin; Deoxyribonucleic acid; Disease Progression; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors; DNA (Cytosine-5-)-Methyltransferases - physiology; DNA Methylation; DNMT; Enhancer of Zeste Homolog 2 Protein; Epigenetics; Experiments; EZH2; Gastric cancer; Gene expression; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma - therapy; Hematology, Oncology and Palliative Medicine; Histone modifications; Histones - metabolism; Humans; Medical prognosis; Mice, Inbred BALB C; Mice, Nude; MicroRNAs - genetics; MicroRNAs - metabolism; miR-200; Polycomb Repressive Complex 2 - antagonists & inhibitors; Polycomb Repressive Complex 2 - physiology; Proteins; RNA polymerase; Stomach Neoplasms - therapy; Tumor Burden; Tumors; Xenograft Model Antitumor Assays; DNA methylation; DNMT; Histone modifications; miR-200; EZH2