Murine model and mechanisms of treatment-induced painful diabetic neuropathy - Nicodemus, Juliet M.; Enriquez, Cynthia; Marquez, Alexandra; Anaya, Carlos J.; Jolivalt, Corinne G. (Neuroscience, 2017)
Keywords: Amines - therapeutic use; Animals; Cyclohexanecarboxylic Acids - therapeutic use; diabetes; Diabetic Neuropathies - complications; Diabetic Neuropathies - genetics; Diabetic Neuropathies - therapy; Disease Models, Animal; Enzyme Inhibitors - pharmacology; Excitatory Amino Acid Antagonists - therapeutic use; Female; gamma-Aminobutyric Acid - therapeutic use; Guanine Nucleotide Exchange Factors - genetics; Guanine Nucleotide Exchange Factors - metabolism; Hyperalgesia - etiology; Hypoglycemic Agents - toxicity; insulin; Insulin - toxicity; insulin neuritis; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Conduction - genetics; Neural Conduction - physiology; Neuralgia - complications; Neuralgia - genetics; Neuralgia - therapy; Neurology; neuropathy; Pain Threshold - physiology; Reaction Time - physiology; Receptor, Insulin - deficiency; Receptor, Insulin - genetics; Receptors, Leptin - genetics; Receptors, Leptin - metabolism; TIND; MNCV; insulin; HFD; IR-KD; neuropathy; IGF1; LFD; PWT; TIND; diabetes; insulin neuritis; treatment-induced painful neuropathy of diabetes; Insulin-like Growth Factor 1; low-fat diet; 50% paw withdrawal threshold; high-fat diet; motor nerve conduction velocity; inducible insulin receptor knockdown