Surveillance for severe hand, foot, and mouth disease from 2009 to 2015 in Jiangsu province: epidemiology, etiology, and disease burden

• Published in: BMC infectious diseases Vol. 19; no. 1; pp. 79 - 18
• Main Authors: Ji, Hong, Fan, Huan, Lu, Peng-xiao, Zhang, Xue-Feng, Ai, Jing, Shi, Chao, Huo, Xiang, Bao, Chang-jun, Shan, Jun, Jin, Yu
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 22.01.2019; BioMed Central; BMC
• Subjects: Analysis; Case studies; Child; Child health; Child, Preschool; China - epidemiology; CNS complication; Coxsackievirus A16; Coxsackievirus infections; Disease burden; Enterovirus - genetics; Enterovirus - isolation & purification; Enterovirus - pathogenicity; Enterovirus A71; Epidemiology; Etiology (Medicine); Female; Genes; Genotype; Genotypes; Hand, Foot and Mouth Disease - complications; Hand, Foot and Mouth Disease - epidemiology; Hand, Foot and Mouth Disease - etiology; Hospitalization - statistics & numerical data; Humans; Infant; Male; Medical research; Mortality; Pediatric diseases; Phylogeny; Risk factors; Serogroup; Severe hand, foot and mouth disease; Viral Proteins - genetics; China; Coxsackievirus A6; Coxsackievirus A10; CNS complication; Enterovirus A71; Disease burden; Epidemiology; Coxsackievirus A16; Pathogen spectrum; Severe hand, foot and mouth disease

Severe hand, foot, and mouth disease (HFMD) is a common childhood illness caused by various enteroviruses. The disease has imposed increased burden on children younger than 5 years old. We aimed to determine the epidemiology, CNS complication, and etiology among severe HFMD patients, in Jiangsu, Chi...