A New Integrated Variable Based on Thermometry, Actimetry and Body Position (TAP) to Evaluate Circadian System Status in Humans

• Published in: PLoS computational biology Vol. 6; no. 11; p. e1000996
• Main Authors: Ortiz-Tudela, Elisabet, Martinez-Nicolas, Antonio, Campos, Manuel, Rol, María Ángeles, Madrid, Juan Antonio
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.11.2010; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Biological clocks; Body temperature; Body Temperature - physiology; Cancer; Chronic illnesses; Circadian rhythm; Circadian Rhythm - physiology; Circadian rhythms; Computational Biology/Synthetic Biology; Computational Biology/Systems Biology; Experiments; Female; Genetic aspects; Health Status Indicators; Humans; Male; Motor Activity - physiology; Neuroscience; Physiological aspects; Physiology; Physiology/Integrative Physiology; Physiology/Pattern Formation; Posture; Posture - physiology; Rodents; Sensitivity and Specificity; Signal Processing, Computer-Assisted; Sleep - physiology; Statistics, Nonparametric; Studies; Variables; Wrist; Spain; Health Status Indicators; Sensitivity & Specificity; Humans; Male; Body Temperature; Circadian Rhythm; Motor Activity; Posture; Wrist; Artifacts; Sleep; Adolescent; Statistics, Nonparametric; Signal Processing, Computer-Assisted; Adult; Female
• ISSN: 1553-7358; 1553-734X; 1553-7358
• DOI: 10.1371/journal.pcbi.1000996

The disruption of the circadian system in humans has been associated with the development of chronic illnesses and the worsening of pre-existing pathologies. Therefore, the assessment of human circadian system function under free living conditions using non-invasive techniques needs further research...