Gut microbiota contributes to high-altitude hypoxia acclimatization of human populations

• Published in: Genome Biology Vol. 25; no. 1; p. 232
• Main Authors: Su, Qian, Zhuang, Dao-Hua, Li, Yu-Chun, Chen, Yu, Wang, Xia-Yan, Ge, Ming-Xia, Xue, Ting-Yue, Zhang, Qi-Yuan, Liu, Xin-Yuan, Yin, Fan-Qian, Han, Yi-Ming, Gao, Zong-Liang, Zhao, Long, Li, Yong-Xuan, Lv, Meng-Jiao, Yang, Li-Qin, Xia, Tian-Rui, Luo, Yong-Jun, Zhang, Zhigang, Kong, Qing-Peng
• Format: Journal Article
• Language: English
• Published: England BioMed Central 28.08.2024; BMC
• Subjects: acclimation; Acclimatization; Adaptation; Adult; Altitude; Altitude Sickness - genetics; Altitude Sickness - microbiology; Animal research; Animals; Bacteria; Blautia; Blautia A; Body mass index; diet; Digestive system; Female; functional diversity; Gastrointestinal Microbiome; Gastrointestinal tract; genetic background; genome; Genomes; genus; Gut microbiota; High-altitude environments; Humans; Hypoxia; Hypoxia - genetics; Hypoxia exposure; Intestinal health; Intestinal microflora; intestinal microorganisms; Intestine; intestines; lifestyle; Longitudinal Studies; Male; Males; Metagenomics; Mice; Microbiota; Middle Aged; nationalities and ethnic groups; phenotype; Phenotype acclimatization; Phenotypes; species; Taxonomy; Time-series; Time-series; Hypoxia exposure; Blautia A; Phenotype acclimatization; Intestinal health

The relationship between human gut microbiota and high-altitude hypoxia acclimatization remains highly controversial. This stems primarily from uncertainties regarding both the potential temporal changes in the microbiota under such conditions and the existence of any dominant or core bacteria that...