Metabolic independence drives gut microbial colonization and resilience in health and disease

• Published in: Genome Biology Vol. 24; no. 1; p. 78
• Main Authors: Watson, Andrea R., Füssel, Jessika, Veseli, Iva, DeLongchamp, Johanna Zaal, Silva, Marisela, Trigodet, Florian, Lolans, Karen, Shaiber, Alon, Fogarty, Emily, Runde, Joseph M., Quince, Christopher, Yu, Michael K., Söylev, Arda, Morrison, Hilary G., Lee, Sonny T. M., Kao, Dina, Rubin, David T., Jabri, Bana, Louie, Thomas, Eren, A. Murat
• Format: Journal Article
• Language: English
• Published: England BioMed Central 17.04.2023; BMC
• Subjects: Amino Acids; biosynthesis; Community composition; community structure; Digestive system; Disease; Dysbacteriosis; Ecology; environmental factors; Fecal Microbiota Transplantation; Fecal microflora; Feces; Gastrointestinal Microbiome; genome; Genomes; Human gut microbiome; human health; Humans; Inflammation; Inflammatory bowel disease; Intestinal microflora; intestinal microorganisms; Metabolic independence; Metabolism; metabolites; Metagenomics; Microbial colonization; microbial communities; Microbial metabolism; microbiome; Microbiomes; Microbiota; Nucleotides; Success; surveys; Taxonomy; Transplantation; Transplants & implants; Vitamins; Microbial colonization; Human gut microbiome; Metabolic independence; Fecal microbiota transplantation; Microbial metabolism

Changes in microbial community composition as a function of human health and disease states have sparked remarkable interest in the human gut microbiome. However, establishing reproducible insights into the determinants of microbial succession in disease has been a formidable challenge. Here we use...