Pulmonary embolism and 529 human blood metabolites: genetic correlation and two-sample Mendelian randomization study - Feng, Ruoyang; Lu, Mengnan; Xu, Jiawen; Zhang, Feng; Yang, Mingyi; Luo, Pan; Xu, Ke; Xu, Peng (BMC genetics, 2022)
Keywords: 5-Hydroxytryptophan; ancestry; Arylamine N-Acetyltransferase; Biobanks; Blood; Blood plasma; Cardiovascular disease; Chromatography; data collection; DNA microarrays; Embolism; Ethanolamine; Fractures; gene expression regulation; genes; Genetic aspects; Genetic correlation; Genome-wide association studies; Genome-Wide Association Study; Genomes; Glycerol; Health aspects; Human blood metabolites; Humans; Linkage Disequilibrium; Mendelian Randomization Analysis - methods; Metabolism; Metabolites; microarray technology; Mortality; phosphates; Pulmonary arteries; Pulmonary embolism; Pulmonary Embolism - genetics; Pulmonary embolisms; Quality control; risk; Risk factors; Software; Statistical analysis; Stearic acid; Surgery; Thromboembolism; transcriptome; Transcriptomes; Variables; China; United Kingdom--UK; Europe; Pulmonary embolism; Genetic correlation; Genome-wide association study; Human blood metabolites