TAD-like single-cell domain structures exist on both active and inactive X chromosomes and persist under epigenetic perturbations - Cheng, Yubao; Liu, Miao; Hu, Mengwei; Wang, Siyuan (Genome Biology, 2021)
Keywords: Binding sites; Cell lines; Chromatin; Chromatin - chemistry; Chromatin folding; Chromosomes, Human, X - chemistry; Cohesin; Computer applications; domain; Epigenesis, Genetic; Epigenetics; Female; females; genome; Genomes; Genomics; Humans; Hybridization; Population; Probability; Single-cell domain; TAD-like structure; Topologically associating domain (TAD); Transcription; Transcription, Genetic; X chromosome; X chromosomes; X inactivation; Chromatin folding; Single-cell domain; Image-based spatial genomics; Multiplexed sequential fluorescence in situ hybridization (FISH); TAD-like structure; Chromatin compaction; X chromosome; 3D genomics; X inactivation; Topologically associating domain (TAD); Chromatin tracing