Fatigue in adults with congenital heart disease aged over 40 years
Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately c...
Saved in:
| Published in | International journal of cardiology congenital heart disease Vol. 21; p. 100601 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Netherlands
Elsevier B.V
01.09.2025
Elsevier |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately complex or complex congenital heart disease compared to controls and (ii) explores the relationship between fatigue, heart disease complexity, clinical characteristics and self-reported New York Heart Association Functional Class (self-reported NYHA class).
The Multidimensional Fatigue Inventory (MFI-20) was applied in 166 patients with moderately complex CHD or complex CHD (44 % females, median age 55.3 years, IQR 47.6–64.8) along with 89 controls (43 % female, median age 54.0, IQR 46.0–65.9). MFI-20 measured general fatigue, physical fatigue, mental fatigue, reduced motivation and reduced activity.
Physical fatigue (severe to very severe) was more common in complex CHD compared with moderately complex CHD (25 % vs. 52 %, p = 0.006). Complex CHD was associated with severe to very severe physical fatigue (odds ratio 3.1 (95 % CI 1.1–9.1). Patients with complex CHD had higher levels of self-reported NYHA class than patients with moderately complex CHD. All dimensions of fatigue were positively associated with self-reported NYHA class.
Patients over the age of 40 with complex CHD were three times more likely to report severe to very severe physical fatigue and reported higher levels of self-reported NYHA class than patients with moderately complex CHD. This highlights the importance of considering CHD complexity in clinical practice.
•Fatigue has been described among adult patients with congenital heart disease (CHD).•We examined fatigue in patients aged over 40 years with moderately complex and complex CHD.•Physical fatigue (severe to very severe) was more common in complex CHD.•Patients with complex CHD reported higher levels of self-reported NYHA class than those with moderately complex CHD. |
|---|---|
| AbstractList | Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately complex or complex congenital heart disease compared to controls and (ii) explores the relationship between fatigue, heart disease complexity, clinical characteristics and self-reported New York Heart Association Functional Class (self-reported NYHA class).
The Multidimensional Fatigue Inventory (MFI-20) was applied in 166 patients with moderately complex CHD or complex CHD (44 % females, median age 55.3 years, IQR 47.6–64.8) along with 89 controls (43 % female, median age 54.0, IQR 46.0–65.9). MFI-20 measured general fatigue, physical fatigue, mental fatigue, reduced motivation and reduced activity.
Physical fatigue (severe to very severe) was more common in complex CHD compared with moderately complex CHD (25 % vs. 52 %, p = 0.006). Complex CHD was associated with severe to very severe physical fatigue (odds ratio 3.1 (95 % CI 1.1–9.1). Patients with complex CHD had higher levels of self-reported NYHA class than patients with moderately complex CHD. All dimensions of fatigue were positively associated with self-reported NYHA class.
Patients over the age of 40 with complex CHD were three times more likely to report severe to very severe physical fatigue and reported higher levels of self-reported NYHA class than patients with moderately complex CHD. This highlights the importance of considering CHD complexity in clinical practice.
•Fatigue has been described among adult patients with congenital heart disease (CHD).•We examined fatigue in patients aged over 40 years with moderately complex and complex CHD.•Physical fatigue (severe to very severe) was more common in complex CHD.•Patients with complex CHD reported higher levels of self-reported NYHA class than those with moderately complex CHD. • Fatigue has been described among adult patients with congenital heart disease (CHD). • We examined fatigue in patients aged over 40 years with moderately complex and complex CHD. • Physical fatigue (severe to very severe) was more common in complex CHD. • Patients with complex CHD reported higher levels of self-reported NYHA class than those with moderately complex CHD. Background Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD) , but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately complex or complex congenital heart disease compared to controls and (ii) explores the relationship between fatigue, heart disease complexity, clinical characteristics and self-reported New York Heart Association Functional Class (self-reported NYHA class). Methods The Multidimensional Fatigue Inventory (MFI-20) was applied in 166 patients with moderately complex CHD or complex CHD (44 % females, median age 55.3 years, IQR 47.6–64.8) along with 89 controls (43 % female, median age 54.0, IQR 46.0–65.9). MFI-20 measured general fatigue, physical fatigue, mental fatigue, reduced motivation and reduced activity. Results Physical fatigue (severe to very severe) was more common in complex CHD compared with moderately complex CHD (25 % vs. 52 %, p = 0.006). Complex CHD was associated with severe to very severe physical fatigue (odds ratio 3.1 (95 % CI 1.1–9.1). Patients with complex CHD had higher levels of self-reported NYHA class than patients with moderately complex CHD. All dimensions of fatigue were positively associated with self-reported NYHA class. Conclusions Patients over the age of 40 with complex CHD were three times more likely to report severe to very severe physical fatigue and reported higher levels of self-reported NYHA class than patients with moderately complex CHD. This highlights the importance of considering CHD complexity in clinical practice. Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD) but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately complex or complex congenital heart disease compared to controls and (ii) explores the relationship between fatigue, heart disease complexity, clinical characteristics and self-reported New York Heart Association Functional Class (self-reported NYHA class). The Multidimensional Fatigue Inventory (MFI-20) was applied in 166 patients with moderately complex CHD or complex CHD (44 % females, median age 55.3 years, IQR 47.6-64.8) along with 89 controls (43 % female, median age 54.0, IQR 46.0-65.9). MFI-20 measured general fatigue, physical fatigue, mental fatigue, reduced motivation and reduced activity. Physical fatigue (severe to very severe) was more common in complex CHD compared with moderately complex CHD (25 % 52 %, = 0.006). Complex CHD was associated with severe to very severe physical fatigue (odds ratio 3.1 (95 % CI 1.1-9.1). Patients with complex CHD had higher levels of self-reported NYHA class than patients with moderately complex CHD. All dimensions of fatigue were positively associated with self-reported NYHA class. Patients over the age of 40 with complex CHD were three times more likely to report severe to very severe physical fatigue and reported higher levels of self-reported NYHA class than patients with moderately complex CHD. This highlights the importance of considering CHD complexity in clinical practice. Background: Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately complex or complex congenital heart disease compared to controls and (ii) explores the relationship between fatigue, heart disease complexity, clinical characteristics and self-reported New York Heart Association Functional Class (self-reported NYHA class). Methods: The Multidimensional Fatigue Inventory (MFI-20) was applied in 166 patients with moderately complex CHD or complex CHD (44 % females, median age 55.3 years, IQR 47.6–64.8) along with 89 controls (43 % female, median age 54.0, IQR 46.0–65.9). MFI-20 measured general fatigue, physical fatigue, mental fatigue, reduced motivation and reduced activity. Results: Physical fatigue (severe to very severe) was more common in complex CHD compared with moderately complex CHD (25 % vs. 52 %, p = 0.006). Complex CHD was associated with severe to very severe physical fatigue (odds ratio 3.1 (95 % CI 1.1–9.1). Patients with complex CHD had higher levels of self-reported NYHA class than patients with moderately complex CHD. All dimensions of fatigue were positively associated with self-reported NYHA class. Conclusions: Patients over the age of 40 with complex CHD were three times more likely to report severe to very severe physical fatigue and reported higher levels of self-reported NYHA class than patients with moderately complex CHD. This highlights the importance of considering CHD complexity in clinical practice. Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately complex or complex congenital heart disease compared to controls and (ii) explores the relationship between fatigue, heart disease complexity, clinical characteristics and self-reported New York Heart Association Functional Class (self-reported NYHA class).BackgroundFatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately complex or complex congenital heart disease compared to controls and (ii) explores the relationship between fatigue, heart disease complexity, clinical characteristics and self-reported New York Heart Association Functional Class (self-reported NYHA class).The Multidimensional Fatigue Inventory (MFI-20) was applied in 166 patients with moderately complex CHD or complex CHD (44 % females, median age 55.3 years, IQR 47.6-64.8) along with 89 controls (43 % female, median age 54.0, IQR 46.0-65.9). MFI-20 measured general fatigue, physical fatigue, mental fatigue, reduced motivation and reduced activity.MethodsThe Multidimensional Fatigue Inventory (MFI-20) was applied in 166 patients with moderately complex CHD or complex CHD (44 % females, median age 55.3 years, IQR 47.6-64.8) along with 89 controls (43 % female, median age 54.0, IQR 46.0-65.9). MFI-20 measured general fatigue, physical fatigue, mental fatigue, reduced motivation and reduced activity.Physical fatigue (severe to very severe) was more common in complex CHD compared with moderately complex CHD (25 % vs. 52 %, p = 0.006). Complex CHD was associated with severe to very severe physical fatigue (odds ratio 3.1 (95 % CI 1.1-9.1). Patients with complex CHD had higher levels of self-reported NYHA class than patients with moderately complex CHD. All dimensions of fatigue were positively associated with self-reported NYHA class.ResultsPhysical fatigue (severe to very severe) was more common in complex CHD compared with moderately complex CHD (25 % vs. 52 %, p = 0.006). Complex CHD was associated with severe to very severe physical fatigue (odds ratio 3.1 (95 % CI 1.1-9.1). Patients with complex CHD had higher levels of self-reported NYHA class than patients with moderately complex CHD. All dimensions of fatigue were positively associated with self-reported NYHA class.Patients over the age of 40 with complex CHD were three times more likely to report severe to very severe physical fatigue and reported higher levels of self-reported NYHA class than patients with moderately complex CHD. This highlights the importance of considering CHD complexity in clinical practice.ConclusionsPatients over the age of 40 with complex CHD were three times more likely to report severe to very severe physical fatigue and reported higher levels of self-reported NYHA class than patients with moderately complex CHD. This highlights the importance of considering CHD complexity in clinical practice. Structured abstractBackgroundFatigue is a symptom that has been described among adult patients with congenital heart disease (CHD) , but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately complex or complex congenital heart disease compared to controls and (ii) explores the relationship between fatigue, heart disease complexity, clinical characteristics and self-reported New York Heart Association Functional Class (self-reported NYHA class). MethodsThe Multidimensional Fatigue Inventory (MFI-20) was applied in 166 patients with moderately complex CHD or complex CHD (44 % females, median age 55.3 years, IQR 47.6–64.8) along with 89 controls (43 % female, median age 54.0, IQR 46.0–65.9). MFI-20 measured general fatigue, physical fatigue, mental fatigue, reduced motivation and reduced activity. ResultsPhysical fatigue (severe to very severe) was more common in complex CHD compared with moderately complex CHD (25 % vs. 52 %, p = 0.006). Complex CHD was associated with severe to very severe physical fatigue (odds ratio 3.1 (95 % CI 1.1–9.1). Patients with complex CHD had higher levels of self-reported NYHA class than patients with moderately complex CHD. All dimensions of fatigue were positively associated with self-reported NYHA class. ConclusionsPatients over the age of 40 with complex CHD were three times more likely to report severe to very severe physical fatigue and reported higher levels of self-reported NYHA class than patients with moderately complex CHD. This highlights the importance of considering CHD complexity in clinical practice. Structured abstract: Background: Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately complex or complex congenital heart disease compared to controls and (ii) explores the relationship between fatigue, heart disease complexity, clinical characteristics and self-reported New York Heart Association Functional Class (self-reported NYHA class). Methods: The Multidimensional Fatigue Inventory (MFI-20) was applied in 166 patients with moderately complex CHD or complex CHD (44 % females, median age 55.3 years, IQR 47.6–64.8) along with 89 controls (43 % female, median age 54.0, IQR 46.0–65.9). MFI-20 measured general fatigue, physical fatigue, mental fatigue, reduced motivation and reduced activity. Results: Physical fatigue (severe to very severe) was more common in complex CHD compared with moderately complex CHD (25 % vs. 52 %, p = 0.006). Complex CHD was associated with severe to very severe physical fatigue (odds ratio 3.1 (95 % CI 1.1–9.1). Patients with complex CHD had higher levels of self-reported NYHA class than patients with moderately complex CHD. All dimensions of fatigue were positively associated with self-reported NYHA class. Conclusions: Patients over the age of 40 with complex CHD were three times more likely to report severe to very severe physical fatigue and reported higher levels of self-reported NYHA class than patients with moderately complex CHD. This highlights the importance of considering CHD complexity in clinical practice. |
| ArticleNumber | 100601 |
| Author | Ternrud, Linda Sparv, David Sandberg, Camilla Christersson, Christina Moons, Philip Hlebowicz, Joanna Mandalenakis, Zacharias Van Bulck, Liesbet Johansson, Bengt |
| Author_xml | – sequence: 1 givenname: Linda orcidid: 0000-0002-7577-8605 surname: Ternrud fullname: Ternrud, Linda email: linda.ternrud@med.lu.se organization: Department of Cardiology, Skåne University Hospital, Lund, Sweden – sequence: 2 givenname: Bengt surname: Johansson fullname: Johansson, Bengt email: bengt.johansson@umu.se organization: Department of Public Health and Clinical Medicine, Umeå University, Sweden – sequence: 3 givenname: David surname: Sparv fullname: Sparv, David email: david.sparv@skane.se organization: Department of Clinical Science, Lund University, Sweden – sequence: 4 givenname: Zacharias surname: Mandalenakis fullname: Mandalenakis, Zacharias email: zacharias.mandalenakis@vgregion.se organization: Adult Congenital Heart Disease Unit, Sahlgrenska University Hospital, Gothenburg, Sweden – sequence: 5 givenname: Christina surname: Christersson fullname: Christersson, Christina email: christina.christersson@medsci.uu.se organization: Department of Medical Sciences, Cardiology, Uppsala University, Sweden – sequence: 6 givenname: Liesbet surname: Van Bulck fullname: Van Bulck, Liesbet email: liesbet.vanbulck@kuleuven.be organization: Department of Public Health and Primary Care, KU Leuven, University of Leuven, Leuven, Belgium – sequence: 7 givenname: Philip surname: Moons fullname: Moons, Philip email: philip.moons@kuleuven.be organization: Department of Public Health and Primary Care, KU Leuven, University of Leuven, Leuven, Belgium – sequence: 8 givenname: Camilla surname: Sandberg fullname: Sandberg, Camilla email: camilla.sandberg@umu.se organization: Department of Community Health and Rehabilitation, Umeå University, Sweden – sequence: 9 givenname: Joanna orcidid: 0000-0002-9515-7240 surname: Hlebowicz fullname: Hlebowicz, Joanna email: joanna.hlebowicz@med.lu.se organization: Department of Cardiology, Skåne University Hospital, Lund, Sweden |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/40698375$$D View this record in MEDLINE/PubMed https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-242284$$DView record from Swedish Publication Index https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-565068$$DView record from Swedish Publication Index |
| BookMark | eNqVkk1v1DAQhiNUREvpP0AoRw7s4u8kEgKVQqFSJQ5UXK1Ze7LrkLVbO9lq_z3eplTdAwJOtuxnnrE87_PiwAePRfGSkjklVL3t5q4zZmXnjDCZj4gi9ElxxJRSM6VqefBof1icpNQRQlidQUmfFYeCqKbmlTwqPp7D4JYjls6XYMd-SOWtG1alCX6J3g3QlyuEOJTWJYSEJSzRlmGDsRSk3Oar9KJ42kKf8OR-PS6uzj9fnX2dXX77cnF2ejkzSolhtmh5Yzm0AEBBVWglWsqgbSomVdvURFpOKLUMFgtLmCFU8kbWTLQc1cLw4-Ji0toAnb6Obg1xqwM4fXcQ4lLndzrTo1bGSIaCS4FGNNjUtLKihbptGl5VtsquN5Mr3eL1uNizfXI_Tu9s46ilkkTVGZ_9A74eNROM1SLzHyY-w2u0Bv0Qod8r27_xbqWXYaNpLid5ONnw-t4Qw82IadBrlwz2PXgMY9KccSaaDPKMvnrc7KHL7xlnQEyAiSGliO0DQonepUl3ekqT3qVJT2nKZe-nMswz3TiMOhmH3qB1Ec2Qf939r8D0zjsD_U_cYurCGH3Oi6Y6MU30911gd3llMmeVVyQL3v1Z8Pf-vwC9h_wg |
| Cites_doi | 10.1186/s12889-017-4623-y 10.1016/j.jacc.2018.08.1029 10.1016/j.jacc.2011.08.025 10.1183/23120541.00079-2017 10.1016/j.ejheart.2006.01.016 10.1016/j.ejcnurse.2008.07.002 10.1177/1474515120963314 10.1016/j.ejcnurse.2006.05.004 10.1161/CIRCULATIONAHA.113.008396 10.1007/s005200100242 10.1093/eurjcn/zvac117 10.1016/j.cjca.2020.03.044 10.1111/chd.12747 10.1016/j.jacc.2016.03.477 10.1177/1474515113496942 10.1016/j.ejcnurse.2011.06.009 10.1016/j.ijcard.2022.06.064 10.1016/J.EJCNURSE.2006.09.004 10.1016/j.ijcard.2014.11.084 10.1161/CIR.0000000000000204 10.1080/09638280601055782 10.1093/ije/dyz009 10.1161/01.CIR.43.3.323 10.1038/bjc.1996.42 10.1161/CIRCULATIONAHA.110.946343 10.1080/02841860601009430 10.1001/jamainternmed.2016.7765 10.1111/j.1744-618X.1996.tb00293.x |
| ContentType | Journal Article |
| Copyright | 2025 The Authors The Authors 2025 The Authors. 2025 The Authors 2025 |
| Copyright_xml | – notice: 2025 The Authors – notice: The Authors – notice: 2025 The Authors. – notice: 2025 The Authors 2025 |
| DBID | 6I. AAFTH AAYXX CITATION NPM 7X8 5PM ADHXS ADTPV AOWAS D8T D93 ZZAVC ACNBI DF2 DOA |
| DOI | 10.1016/j.ijcchd.2025.100601 |
| DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access CrossRef PubMed MEDLINE - Academic PubMed Central (Full Participant titles) SWEPUB Umeå universitet full text SwePub SwePub Articles SWEPUB Freely available online SWEPUB Umeå universitet SwePub Articles full text SWEPUB Uppsala universitet full text SWEPUB Uppsala universitet DOAJ Open Access Full Text |
| DatabaseTitle | CrossRef PubMed MEDLINE - Academic |
| DatabaseTitleList | PubMed MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Open Access Full Text url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 2666-6685 |
| EndPage | 100601 |
| ExternalDocumentID | oai_doaj_org_article_6cc52e4354ec49e9817d4fa8f99377d7 oai_DiVA_org_uu_565068 oai_DiVA_org_umu_242284 PMC12280406 40698375 10_1016_j_ijcchd_2025_100601 S2666668525000370 1_s2_0_S2666668525000370 |
| Genre | Journal Article |
| GroupedDBID | .1- .FO 0R~ 1P~ AAEDW AALRI AAXUO AAYWO ACVFH ADCNI ADVLN AEUPX AFJKZ AFPUW AFRHN AIGII AITUG AJUYK AKBMS AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ APXCP EBS FDB GROUPED_DOAJ M~E OK1 ROL RPM Z5R AFCTW 6I. AAFTH AAYXX CITATION NPM 7X8 5PM ADHXS ADTPV AOWAS D8T D93 ZZAVC ACNBI DF2 |
| ID | FETCH-LOGICAL-c664t-bf39d3afaaa1a67ed5ed12af97256f9805d3011d2abbd02c015395824f3e6bc3 |
| IEDL.DBID | DOA |
| ISSN | 2666-6685 |
| IngestDate | Wed Aug 27 01:30:35 EDT 2025 Thu Aug 21 06:26:47 EDT 2025 Thu Aug 21 06:55:28 EDT 2025 Thu Aug 21 18:25:16 EDT 2025 Thu Jul 24 01:46:55 EDT 2025 Sat Jul 26 01:47:05 EDT 2025 Thu Jul 24 01:59:30 EDT 2025 Sat Aug 09 17:31:21 EDT 2025 Fri Aug 01 03:32:42 EDT 2025 Tue Aug 26 16:32:07 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | Fatigue Patient-reported outcome Congenital heart disease MFI-20 |
| Language | English |
| License | This is an open access article under the CC BY license. 2025 The Authors. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c664t-bf39d3afaaa1a67ed5ed12af97256f9805d3011d2abbd02c015395824f3e6bc3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation. |
| ORCID | 0000-0002-7577-8605 0000-0002-9515-7240 |
| OpenAccessLink | https://doaj.org/article/6cc52e4354ec49e9817d4fa8f99377d7 |
| PMID | 40698375 |
| PQID | 3232490633 |
| PQPubID | 23479 |
| PageCount | 1 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_6cc52e4354ec49e9817d4fa8f99377d7 swepub_primary_oai_DiVA_org_uu_565068 swepub_primary_oai_DiVA_org_umu_242284 pubmedcentral_primary_oai_pubmedcentral_nih_gov_12280406 proquest_miscellaneous_3232490633 pubmed_primary_40698375 crossref_primary_10_1016_j_ijcchd_2025_100601 elsevier_sciencedirect_doi_10_1016_j_ijcchd_2025_100601 elsevier_clinicalkeyesjournals_1_s2_0_S2666668525000370 elsevier_clinicalkey_doi_10_1016_j_ijcchd_2025_100601 |
| PublicationCentury | 2000 |
| PublicationDate | 2025-09-01 |
| PublicationDateYYYYMMDD | 2025-09-01 |
| PublicationDate_xml | – month: 09 year: 2025 text: 2025-09-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | Netherlands |
| PublicationPlace_xml | – name: Netherlands |
| PublicationTitle | International journal of cardiology congenital heart disease |
| PublicationTitleAlternate | Int J Cardiol Congenit Heart Dis |
| PublicationYear | 2025 |
| Publisher | Elsevier B.V Elsevier |
| Publisher_xml | – name: Elsevier B.V – name: Elsevier |
| References | Moons, Luyckx, Thomet, Budts, Enomoto, Sluman (bib10) 2021; 37 US Department of Health and Human Service Food and Drug (bib11) 2009 Ternrud, Hlebowicz, Sandberg, Johansson, Sparv (bib18) 2021; 29 Goossens, Fleck, Canobbio, Harrison, Moons (bib7) 2013; 12 Staniute, Bunevicius, Brozaitiene, Bunevicius (bib12) 2014; 13 Hagelin, Wengström, Runesdotter, Furst (bib22) 2007; 46 Falk, Patel, Swedberg, Ekman (bib26) 2009; 8 Bay, Lämås, Berghammer, Sandberg, Johansson (bib31) 2021; 20 Moons, Bovijn, Budts, Belmans, Gewillig (bib2) 2010; 122 Falk, Swedberg, Gaston-Johansson, I (bib13) 2007; 6 Tartavoulle, Karpinski, Aubin, Kluger, Distler, Saketkoo (bib14) 2018; 4 Van Bulck, Kovacs, Goossens, Luyckx, Zaidi, Wang (bib19) 2022; 363 Smets, Garssen, Cull, de Haes (bib16) 1996; 73 Engberg, Segerstedt, Waller, Wennberg, Eliasson (bib29) 2017; 17 van der Linde, Konings, Slager, Witsenburg, Helbing, Takkenberg (bib4) 2011; 58 Marelli, Ionescu-Ittu, Mackie, Guo, Dendukuri, Kaouache (bib5) 2014; 130 Tiesinga, Dassen, Halfens (bib15) 1996; 7 Higa, Lennie, Chung, Tsuchihashi-Makaya (bib27) 2023; 22 Bhatt, Foster, Kuehl, Alpert, Brabeck, Crumb (bib6) 2015; 131 Mitchell, Korones, Berendes (bib20) 1971; 43 Stout, Daniels, Aboulhosn, Bozkurt, Broberg, Colman (bib17) 2019; 73 Furst, Ahsberg (bib21) 2001; 9 Hägglund, Boman, Olofsson, Brulin (bib28) 2007; 6 Olsson (bib25) 2011 Liu, Chen, Zuhlke, Black, Choy, Li (bib1) 2019; 48 Falk, Swedberg, Gaston-Johansson, Ekman (bib30) 2006; 8 Mandalenakis, Rosengren, Skoglund, Lappas, Eriksson, Dellborg (bib3) 2017; 177 Björk (bib24) 2020 Apers, Kovacs, Luyckx, Thomet, Budts, Enomoto (bib9) 2016; 67 Ericsson, Mannerkorpi (bib23) 2007; 29 Sluman, Apers, Sluiter, Nieuwenhuijsen, Moons, Luyckx (bib32) 2019; 14 Apers, Kovacs, Luyckx, Alday, Berghammer, Budts (bib8) 2015; 179 Bhatt (10.1016/j.ijcchd.2025.100601_bib6) 2015; 131 Apers (10.1016/j.ijcchd.2025.100601_bib8) 2015; 179 Hägglund (10.1016/j.ijcchd.2025.100601_bib28) 2007; 6 Moons (10.1016/j.ijcchd.2025.100601_bib10) 2021; 37 Goossens (10.1016/j.ijcchd.2025.100601_bib7) 2013; 12 Mitchell (10.1016/j.ijcchd.2025.100601_bib20) 1971; 43 Furst (10.1016/j.ijcchd.2025.100601_bib21) 2001; 9 Sluman (10.1016/j.ijcchd.2025.100601_bib32) 2019; 14 Engberg (10.1016/j.ijcchd.2025.100601_bib29) 2017; 17 Falk (10.1016/j.ijcchd.2025.100601_bib13) 2007; 6 Stout (10.1016/j.ijcchd.2025.100601_bib17) 2019; 73 Björk (10.1016/j.ijcchd.2025.100601_bib24) 2020 van der Linde (10.1016/j.ijcchd.2025.100601_bib4) 2011; 58 Marelli (10.1016/j.ijcchd.2025.100601_bib5) 2014; 130 Apers (10.1016/j.ijcchd.2025.100601_bib9) 2016; 67 US Department of Health and Human Service Food and Drug (10.1016/j.ijcchd.2025.100601_bib11) 2009 Bay (10.1016/j.ijcchd.2025.100601_bib31) 2021; 20 Liu (10.1016/j.ijcchd.2025.100601_bib1) 2019; 48 Olsson (10.1016/j.ijcchd.2025.100601_bib25) 2011 Moons (10.1016/j.ijcchd.2025.100601_bib2) 2010; 122 Tartavoulle (10.1016/j.ijcchd.2025.100601_bib14) 2018; 4 Mandalenakis (10.1016/j.ijcchd.2025.100601_bib3) 2017; 177 Tiesinga (10.1016/j.ijcchd.2025.100601_bib15) 1996; 7 Van Bulck (10.1016/j.ijcchd.2025.100601_bib19) 2022; 363 Higa (10.1016/j.ijcchd.2025.100601_bib27) 2023; 22 Falk (10.1016/j.ijcchd.2025.100601_bib30) 2006; 8 Falk (10.1016/j.ijcchd.2025.100601_bib26) 2009; 8 Staniute (10.1016/j.ijcchd.2025.100601_bib12) 2014; 13 Hagelin (10.1016/j.ijcchd.2025.100601_bib22) 2007; 46 Ericsson (10.1016/j.ijcchd.2025.100601_bib23) 2007; 29 Smets (10.1016/j.ijcchd.2025.100601_bib16) 1996; 73 Ternrud (10.1016/j.ijcchd.2025.100601_bib18) 2021; 29 |
| References_xml | – year: 2011 ident: bib25 publication-title: Forskningsprocessen – volume: 6 start-page: 99 year: 2007 end-page: 104 ident: bib13 article-title: Ekman Fatigue is a prevalent and severe symptom associated with uncertainty and sense of coherence in patients with chronic heart failure publication-title: Eur J Cardiovasc Nurs – volume: 8 start-page: 91 year: 2009 end-page: 96 ident: bib26 article-title: Fatigue in patients with chronic heart failure - a burden associated with emotional and symptom distress publication-title: Eur J Cardiovasc Nurs – volume: 122 start-page: 2264 year: 2010 end-page: 2272 ident: bib2 article-title: Temporal trends in survival to adulthood among patients born with congenital heart disease from 1970 to 1992 in Belgium publication-title: Circulation – year: 2009 ident: bib11 publication-title: Silver Spring MD: Food and Drug Administration – volume: 73 start-page: 241 year: 1996 end-page: 245 ident: bib16 article-title: Application of the multidimensional fatigue inventory (MFI-20) in cancer patients receiving radiotherapy publication-title: Br J Cancer – volume: 4 start-page: 79 year: 2018 end-page: 2017 ident: bib14 article-title: Multidimensional fatigue in pulmonary hypertension: prevalence, severity and predictors publication-title: ERJ Open Res – year: 2020 ident: bib24 article-title: Praktisk statistik för medicin och hälsa – volume: 9 start-page: 355 year: 2001 end-page: 360 ident: bib21 article-title: Dimensions of fatigue during radiotherapy. An application of the multidimensional fatigue inventory publication-title: Support Care Cancer – volume: 29 start-page: 1 year: 2021 end-page: 8 ident: bib18 article-title: Prevalence of fatigue in adults with congenital heart disease publication-title: Cardiol Young. Oct – volume: 179 start-page: 334 year: 2015 end-page: 342 ident: bib8 article-title: Assessment of Patterns of patient-reported outcomes in adults with congenital heart disease - international study (APPROACH-IS): rationale, design, and methods publication-title: Int J Cardiol – volume: 48 start-page: 455 year: 2019 end-page: 463 ident: bib1 article-title: Global birth prevalence of congenital heart defects 1970-2017: updated systematic review and meta-analysis of 260 studies publication-title: Int J Epidemiol – volume: 130 start-page: 749 year: 2014 end-page: 756 ident: bib5 article-title: Lifetime prevalence of congenital heart disease in the general population from 2000 to 2010 publication-title: Circulation – volume: 22 start-page: 647 year: 2023 end-page: 654 ident: bib27 article-title: Associations of multidimensional fatigue with the physical, psychological, and situational factors in outpatients with heart failure: a cross-sectional study publication-title: Eur J Cardiovasc Nurs – volume: 8 start-page: 744 year: 2006 end-page: 749 ident: bib30 article-title: Fatigue and anaemia in patients with chronic heart failure publication-title: Eur J Heart Fail – volume: 67 start-page: 2237 year: 2016 end-page: 2245 ident: bib9 article-title: Quality of life of adults with congenital heart disease in 15 countries: evaluating country-specific characteristics publication-title: J Am Coll Cardiol – volume: 13 start-page: 338 year: 2014 end-page: 344 ident: bib12 article-title: Relationship of health-related quality of life with fatigue and exercise capacity in patients with coronary artery disease publication-title: Eur J Cardiovasc Nurs – volume: 131 start-page: 1884 year: 2015 end-page: 1931 ident: bib6 article-title: Congenital heart disease in the older adult: a scientific statement from the American Heart Association publication-title: Circulation – volume: 14 start-page: 362 year: 2019 end-page: 371 ident: bib32 article-title: Education as important predictor for successful employment in adults with congenital heart disease worldwide publication-title: Congenit Heart Dis – volume: 177 start-page: 224 year: 2017 end-page: 230 ident: bib3 article-title: Survivorship in children and young adults with congenital heart disease in Sweden publication-title: JAMA Intern Med – volume: 12 start-page: 7 year: 2013 end-page: 16 ident: bib7 article-title: Development of an international research agenda for adult congenital heart disease nursing publication-title: Eur J Cardiovasc Nurs – volume: 58 start-page: 2241 year: 2011 end-page: 2247 ident: bib4 article-title: Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis publication-title: J Am Coll Cardiol – volume: 73 start-page: e81 year: 2019 end-page: e192 ident: bib17 article-title: 2018 AHA/ACC guideline for the management of adults with congenital heart disease: a report of the American college of cardiology/American heart association task force on clinical practice guidelines publication-title: J Am Coll Cardiol – volume: 363 start-page: 30 year: 2022 end-page: 39 ident: bib19 article-title: Rationale, design and methodology of APPROACH-IS II: international study of patient-reported outcomes and frailty phenotyping in adults with congenital heart disease publication-title: Int J Cardiol – volume: 43 start-page: 323 year: 1971 end-page: 332 ident: bib20 article-title: Congenital heart disease in 56109 births publication-title: Circulation – volume: 29 start-page: 1665 year: 2007 end-page: 1670 ident: bib23 article-title: Assessment of fatigue in patients with fibromyalgia and chronic widespread pain. Reliability and validity of the Swedish version of the MFI-20 publication-title: Disabil Rehabil – volume: 6 start-page: 208 year: 2007 end-page: 215 ident: bib28 article-title: Fatigue and health-related quality of life in elderly patients with and without heart failure in primary healthcare publication-title: Eur J Cardiovasc Nurs – volume: 20 start-page: 276 year: 2021 end-page: 284 ident: bib31 article-title: Enablers and barriers for being physically active: experiences from adults with congenital heart disease publication-title: Eur J Cardiovasc Nurs – volume: 37 start-page: 215 year: 2021 end-page: 223 ident: bib10 article-title: Physical functioning, mental health, and quality of life in different congenital heart defects: comparative analysis in 3538 patients from 15 countries publication-title: Can J Cardiol – volume: 7 start-page: 51 year: 1996 end-page: 62 ident: bib15 article-title: Fatigue: a summary of the definitions, dimensions, and indicators publication-title: Nurs Diagn – volume: 17 start-page: 654 year: 2017 ident: bib29 article-title: Fatigue in the general population- associations to age, sex, socioeconomic status, physical activity, sitting time and self-rated health: the northern Sweden MONICA study 2014 publication-title: BMC Public Health – volume: 46 start-page: 97 year: 2007 end-page: 104 ident: bib22 article-title: The psychometric properties of the Swedish Multidimensional Fatigue Inventory MFI-20 in four different populations publication-title: Acta Oncol – volume: 17 start-page: 654 year: 2017 ident: 10.1016/j.ijcchd.2025.100601_bib29 article-title: Fatigue in the general population- associations to age, sex, socioeconomic status, physical activity, sitting time and self-rated health: the northern Sweden MONICA study 2014 publication-title: BMC Public Health doi: 10.1186/s12889-017-4623-y – volume: 73 start-page: e81 year: 2019 ident: 10.1016/j.ijcchd.2025.100601_bib17 article-title: 2018 AHA/ACC guideline for the management of adults with congenital heart disease: a report of the American college of cardiology/American heart association task force on clinical practice guidelines publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2018.08.1029 – year: 2020 ident: 10.1016/j.ijcchd.2025.100601_bib24 – volume: 58 start-page: 2241 year: 2011 ident: 10.1016/j.ijcchd.2025.100601_bib4 article-title: Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2011.08.025 – volume: 29 start-page: 1 year: 2021 ident: 10.1016/j.ijcchd.2025.100601_bib18 article-title: Prevalence of fatigue in adults with congenital heart disease publication-title: Cardiol Young. Oct – volume: 4 start-page: 79 year: 2018 ident: 10.1016/j.ijcchd.2025.100601_bib14 article-title: Multidimensional fatigue in pulmonary hypertension: prevalence, severity and predictors publication-title: ERJ Open Res doi: 10.1183/23120541.00079-2017 – volume: 8 start-page: 744 year: 2006 ident: 10.1016/j.ijcchd.2025.100601_bib30 article-title: Fatigue and anaemia in patients with chronic heart failure publication-title: Eur J Heart Fail doi: 10.1016/j.ejheart.2006.01.016 – volume: 8 start-page: 91 year: 2009 ident: 10.1016/j.ijcchd.2025.100601_bib26 article-title: Fatigue in patients with chronic heart failure - a burden associated with emotional and symptom distress publication-title: Eur J Cardiovasc Nurs doi: 10.1016/j.ejcnurse.2008.07.002 – volume: 20 start-page: 276 year: 2021 ident: 10.1016/j.ijcchd.2025.100601_bib31 article-title: Enablers and barriers for being physically active: experiences from adults with congenital heart disease publication-title: Eur J Cardiovasc Nurs doi: 10.1177/1474515120963314 – volume: 6 start-page: 99 year: 2007 ident: 10.1016/j.ijcchd.2025.100601_bib13 article-title: Ekman Fatigue is a prevalent and severe symptom associated with uncertainty and sense of coherence in patients with chronic heart failure publication-title: Eur J Cardiovasc Nurs doi: 10.1016/j.ejcnurse.2006.05.004 – volume: 130 start-page: 749 year: 2014 ident: 10.1016/j.ijcchd.2025.100601_bib5 article-title: Lifetime prevalence of congenital heart disease in the general population from 2000 to 2010 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.113.008396 – volume: 9 start-page: 355 year: 2001 ident: 10.1016/j.ijcchd.2025.100601_bib21 article-title: Dimensions of fatigue during radiotherapy. An application of the multidimensional fatigue inventory publication-title: Support Care Cancer doi: 10.1007/s005200100242 – volume: 22 start-page: 647 year: 2023 ident: 10.1016/j.ijcchd.2025.100601_bib27 article-title: Associations of multidimensional fatigue with the physical, psychological, and situational factors in outpatients with heart failure: a cross-sectional study publication-title: Eur J Cardiovasc Nurs doi: 10.1093/eurjcn/zvac117 – volume: 37 start-page: 215 year: 2021 ident: 10.1016/j.ijcchd.2025.100601_bib10 article-title: Physical functioning, mental health, and quality of life in different congenital heart defects: comparative analysis in 3538 patients from 15 countries publication-title: Can J Cardiol doi: 10.1016/j.cjca.2020.03.044 – year: 2011 ident: 10.1016/j.ijcchd.2025.100601_bib25 – volume: 14 start-page: 362 year: 2019 ident: 10.1016/j.ijcchd.2025.100601_bib32 article-title: Education as important predictor for successful employment in adults with congenital heart disease worldwide publication-title: Congenit Heart Dis doi: 10.1111/chd.12747 – volume: 67 start-page: 2237 year: 2016 ident: 10.1016/j.ijcchd.2025.100601_bib9 article-title: Quality of life of adults with congenital heart disease in 15 countries: evaluating country-specific characteristics publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2016.03.477 – volume: 13 start-page: 338 year: 2014 ident: 10.1016/j.ijcchd.2025.100601_bib12 article-title: Relationship of health-related quality of life with fatigue and exercise capacity in patients with coronary artery disease publication-title: Eur J Cardiovasc Nurs doi: 10.1177/1474515113496942 – volume: 12 start-page: 7 year: 2013 ident: 10.1016/j.ijcchd.2025.100601_bib7 article-title: Development of an international research agenda for adult congenital heart disease nursing publication-title: Eur J Cardiovasc Nurs doi: 10.1016/j.ejcnurse.2011.06.009 – volume: 363 start-page: 30 year: 2022 ident: 10.1016/j.ijcchd.2025.100601_bib19 article-title: Rationale, design and methodology of APPROACH-IS II: international study of patient-reported outcomes and frailty phenotyping in adults with congenital heart disease publication-title: Int J Cardiol doi: 10.1016/j.ijcard.2022.06.064 – volume: 6 start-page: 208 year: 2007 ident: 10.1016/j.ijcchd.2025.100601_bib28 article-title: Fatigue and health-related quality of life in elderly patients with and without heart failure in primary healthcare publication-title: Eur J Cardiovasc Nurs doi: 10.1016/J.EJCNURSE.2006.09.004 – volume: 179 start-page: 334 year: 2015 ident: 10.1016/j.ijcchd.2025.100601_bib8 article-title: Assessment of Patterns of patient-reported outcomes in adults with congenital heart disease - international study (APPROACH-IS): rationale, design, and methods publication-title: Int J Cardiol doi: 10.1016/j.ijcard.2014.11.084 – volume: 131 start-page: 1884 year: 2015 ident: 10.1016/j.ijcchd.2025.100601_bib6 article-title: Congenital heart disease in the older adult: a scientific statement from the American Heart Association publication-title: Circulation doi: 10.1161/CIR.0000000000000204 – volume: 29 start-page: 1665 year: 2007 ident: 10.1016/j.ijcchd.2025.100601_bib23 article-title: Assessment of fatigue in patients with fibromyalgia and chronic widespread pain. Reliability and validity of the Swedish version of the MFI-20 publication-title: Disabil Rehabil doi: 10.1080/09638280601055782 – volume: 48 start-page: 455 year: 2019 ident: 10.1016/j.ijcchd.2025.100601_bib1 article-title: Global birth prevalence of congenital heart defects 1970-2017: updated systematic review and meta-analysis of 260 studies publication-title: Int J Epidemiol doi: 10.1093/ije/dyz009 – volume: 43 start-page: 323 year: 1971 ident: 10.1016/j.ijcchd.2025.100601_bib20 article-title: Congenital heart disease in 56109 births publication-title: Circulation doi: 10.1161/01.CIR.43.3.323 – volume: 73 start-page: 241 year: 1996 ident: 10.1016/j.ijcchd.2025.100601_bib16 article-title: Application of the multidimensional fatigue inventory (MFI-20) in cancer patients receiving radiotherapy publication-title: Br J Cancer doi: 10.1038/bjc.1996.42 – volume: 122 start-page: 2264 year: 2010 ident: 10.1016/j.ijcchd.2025.100601_bib2 article-title: Temporal trends in survival to adulthood among patients born with congenital heart disease from 1970 to 1992 in Belgium publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.110.946343 – year: 2009 ident: 10.1016/j.ijcchd.2025.100601_bib11 article-title: Guidance for industry. Patient-reported outcome measures: use in medical product development to support labeling claims publication-title: Silver Spring MD: Food and Drug Administration – volume: 46 start-page: 97 year: 2007 ident: 10.1016/j.ijcchd.2025.100601_bib22 article-title: The psychometric properties of the Swedish Multidimensional Fatigue Inventory MFI-20 in four different populations publication-title: Acta Oncol doi: 10.1080/02841860601009430 – volume: 177 start-page: 224 year: 2017 ident: 10.1016/j.ijcchd.2025.100601_bib3 article-title: Survivorship in children and young adults with congenital heart disease in Sweden publication-title: JAMA Intern Med doi: 10.1001/jamainternmed.2016.7765 – volume: 7 start-page: 51 year: 1996 ident: 10.1016/j.ijcchd.2025.100601_bib15 article-title: Fatigue: a summary of the definitions, dimensions, and indicators publication-title: Nurs Diagn doi: 10.1111/j.1744-618X.1996.tb00293.x |
| SSID | ssj0002810051 |
| Score | 2.3021643 |
| Snippet | Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and impact of fatigue on the... Structured abstractBackgroundFatigue is a symptom that has been described among adult patients with congenital heart disease (CHD) , but the prevalence and... Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD) but the prevalence and impact of fatigue on the patient's... • Fatigue has been described among adult patients with congenital heart disease (CHD). • We examined fatigue in patients aged over 40 years with moderately... Background: Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and impact of fatigue on... Background Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD) , but the prevalence and impact of fatigue on... Structured abstract: Background: Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and... |
| SourceID | doaj swepub pubmedcentral proquest pubmed crossref elsevier |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Publisher |
| StartPage | 100601 |
| SubjectTerms | Cardiovascular Congenital heart disease Fatigue MFI-20 Original Patient-reported outcome |
| Title | Fatigue in adults with congenital heart disease aged over 40 years |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S2666668525000370 https://www.clinicalkey.es/playcontent/1-s2.0-S2666668525000370 https://dx.doi.org/10.1016/j.ijcchd.2025.100601 https://www.ncbi.nlm.nih.gov/pubmed/40698375 https://www.proquest.com/docview/3232490633 https://pubmed.ncbi.nlm.nih.gov/PMC12280406 https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-242284 https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-565068 https://doaj.org/article/6cc52e4354ec49e9817d4fa8f99377d7 |
| Volume | 21 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Nb9QwELVQT1wQiK8ArYwE3CIcx07sYwusKiS4UFBvluMPmpVIEdkc-PedsZNqoyLKgT1uMonyZpx5scdvCHmlGq9k69rSqjqWQrmu1J2Npew0EOioKy9w7_Cnz83pV_HxXJ7vtfrCmrAsD5yBe9s4J3mApC6CEzpoVbVeRKsiJtbWp33kkPP2Pqa2acqownBb9sqlgq5-69wFioNyibUBzdwHZslFSbJ_lZJuUs6blZMrfdGUkzb3yb2ZTNLj_BAPyJ0wPCQnGwD7-xRoP9CkrjFSnGyl8OELwYI9Qih2sd7ReW2GwhvFU6zkpILR33BofETONh_O3p2Wc6eE0jWN2JVdrLWvbbTWVrZpg5fBV9xG3QKjiVox6XEge267zjPugAPUWiouYh2aztWPycFwOYSnhGrXCSttG7gWgjm4Gpg2XEgvPWOeFaRcIDM_sx6GWQrFtiZDbBBikyEuyAnien0uqlmnP8DHZvaxuc3HBZGLV8yyYRRecXCh_pabt3-yC-M8TkdTmZEbZr4ATYGfwjVeVORh-5YzFckU4x_u-XIJGwMjFZdf7BAup9HUSF41UMK6IE9yGF3DgvuPVd3KgqhVgK1wWx8Z-oukBl6hoBHYF-RNjsWVzfv-23HCevoxGY56b6Igr_964mSA5LNGPfsfrntO7iI4uSrvBTnY_ZrCIdC4XXeURuxRml-7AsZ5RwA |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Fatigue+in+adults+with+congenital+heart+disease+aged+over+40+years&rft.jtitle=International+journal+of+cardiology+congenital+heart+disease&rft.au=Ternrud%2C+Linda&rft.au=Johansson%2C+Bengt&rft.au=Sparv%2C+David&rft.au=Mandalenakis%2C+Zacharias&rft.date=2025-09-01&rft.issn=2666-6685&rft.eissn=2666-6685&rft.volume=21&rft_id=info:doi/10.1016%2Fj.ijcchd.2025.100601&rft.externalDocID=oai_DiVA_org_umu_242284 |
| thumbnail_m | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F26666685%2Fcov200h.gif |