Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses

We summarized the most recent findings on the role of autophagy in antiviral immune response. We described how viruses have developed strategies to subvert the autophagic process. A particular attention has been given to Epstein-Barr and Kaposi’s sarcoma associated Herpesvirus, viruses studied for m...

Full description

Saved in:
Bibliographic Details
Published inJournal of Immunology Research Vol. 2015; no. 2015; pp. 1 - 9
Main Authors Cirone, Mara, Faggioni, Alberto, Granato, Marisa, Santarelli, Roberta
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 01.01.2015
Hindawi Limited
Wiley
Subjects
Antigens
Apoptosis
Autophagy
Autophagy (Cytology)
Autophagy - immunology
Carcinogenesis - immunology
Cytokines
Genetic aspects
Herpesviridae - immunology
Herpesvirus
Herpesviruses
Host-Pathogen Interactions - immunology
Humans
Immune Evasion - immunology
Immune response
Immune system
Immunology
Measles
Peptides
Physiological aspects
Proteins
Review
Virus Replication - immunology
Viruses
Italy
Online AccessGet full text

Cover

More Information
Summary:We summarized the most recent findings on the role of autophagy in antiviral immune response. We described how viruses have developed strategies to subvert the autophagic process. A particular attention has been given to Epstein-Barr and Kaposi’s sarcoma associated Herpesvirus, viruses studied for many years in our laboratory. These two viruses belong to γ-Herpesvirus subfamily and are associated with several human cancers. Besides the effects on the immune response, we have described how autophagy subversion by viruses may also concur to the enhancement of their replication and to viral tumorigenesis.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ObjectType-Article-1
ObjectType-Feature-2
Academic Editor: Eyad Elkord
ISSN:2314-8861
2314-7156
DOI:10.1155/2015/546063