Clinical effects of a hop [Humulus lupulus] water extract on Japanese cedar [Cryptomeria japonica] pollinosis during the pollen season: A double-blind, placebo-controlled trial

• Published in: Bioscience, biotechnology, and biochemistry Vol. 71; no. 8; pp. 1955 - 1962
• Main Authors: Segawa, S.(Sapporo Breweries Ltd., Yaizu, Shizuoka (Japan). Frontier Labs. of Value Creation), Takata, Y, Wakita, Y, Kaneko, T, Kaneda, H, Watari, J, Enomoto, T
• Format: Journal Article
• Language: English
• Published: Tokyo Japan Society for Bioscience, Biotechnology, and Agrochemistry 01.08.2007; Japan Society for Bioscience Biotechnology and Agrochemistry
• Subjects: ADMINISTRACION ORAL; ADMINISTRATION ORALE; Adult; AGUA; allergy; Anti-Allergic Agents - therapeutic use; biochemistry; Biological and medical sciences; biotechnology; blood; clinical examination; CLINICAL TRIALS; color; Cryptomeria - immunology; CRYPTOMERIA JAPONICA; Double-Blind Method; EAU; ENSAYOS CLINICOS; eosinophil; Eosinophils - drug effects; ESSAI CLINIQUE; EXTRACTOS; EXTRACTS; EXTRAIT; Female; Fundamental and applied biological sciences. Psychology; hay fever; hop water extract; human clinical trial; Humans; Humulus - chemistry; HUMULUS LUPULUS; HYPERSENSITIVITY; Japan; Japanese cedar pollinosis; Male; nose; ORAL ADMINISTRATION; Placebos; Plant Extracts - administration & dosage; POLEN; POLLEN; pollen season; REACCIONES ALERGICAS; REACTION ALLERGIQUE; Rhinitis, Allergic, Seasonal - drug therapy; Treatment Outcome; WATER; Japan; Water; Human; human clinical trial; Allergy; Extract; Japanese cedar pollinosis; Eosinophil; Cryptomeria japonica; Gymnospermae; Clinical trial; Coniferales; Spermatophyta; Pollen; hop water extract

The clinical effects of an oral administration of a hop water extract (HWE) on the improvement of Japanese cedar pollinosis (JCPsis) symptoms were investigated. In a double-blind, placebo-controlled trial, 39 subjects took a drink containing either 100 mg of HWE or a placebo for 12 weeks during the...