Trypanosoma brucei modifies the tsetse salivary composition, altering the fly feeding behavior that favors parasite transmission

• Published in: PLoS pathogens Vol. 6; no. 6; p. e1000926
• Main Authors: Van Den Abbeele, Jan, Caljon, Guy, De Ridder, Karin, De Baetselier, Patrick, Coosemans, Marc
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.06.2010; Public Library of Science (PLoS)
• Subjects: Animals; Blood Coagulation; Blood platelets; Disease; Disease transmission; Feeding Behavior; Glossina; Health aspects; Host-Parasite Interactions; Humans; Infectious Diseases/Neglected Tropical Diseases; Infectious Diseases/Protozoal Infections; Insects; Microbiology/Parasitology; Molecular Sequence Data; Parasites; Parasitic diseases; Platelet Aggregation; Proteins; Saliva - chemistry; Salivary Glands - parasitology; Stress, Physiological; Thrombin - metabolism; Trypanosoma brucei; Trypanosoma brucei brucei - physiology; Trypanosomiasis, African - transmission; Tsetse Flies - metabolism; Tsetse Flies - parasitology; Belgium; Africa

Tsetse flies are the notorious transmitters of African trypanosomiasis, a disease caused by the Trypanosoma parasite that affects humans and livestock on the African continent. Metacyclic infection rates in natural tsetse populations with Trypanosoma brucei, including the two human-pathogenic subspe...