The HA and NS Genes of Human H5N1 Influenza A Virus Contribute to High Virulence in Ferrets - Imai, Hirotaka; Shinya, Kyoko; Takano, Ryo; Kiso, Maki; Muramoto, Yukiko; Sakabe, Saori; Murakami, Shin; Ito, Mutsumi; Yamada, Shinya; Le, Mai thi Quynh; Nidom, Chairul A.; Sakai-Tagawa, Yuko; et al. (PLoS pathogens, 2010)
Keywords: Amino acids; Animal models; Animals; Avian flu; Avian influenza viruses; Cells, Cultured; Diseases; Dogs; Erythrocytes; Experiments; Ferrets; Genes; Genetic aspects; Grants; Hemagglutinin Glycoproteins, Influenza Virus - genetics; Hemagglutinin Glycoproteins, Influenza Virus - metabolism; Hemagglutinins; Humans; Infection; Infections; Infectious Diseases; Infectious Diseases/Viral Infections; Influenza A; Influenza A virus; Influenza A Virus, H5N1 Subtype - isolation & purification; Influenza A Virus, H5N1 Subtype - pathogenicity; Influenza virus; Influenza, Human - genetics; Influenza, Human - pathology; Influenza, Human - virology; Interferon; Interferons - metabolism; Kidney - cytology; Kidney - metabolism; Kidney - virology; Lethality; Lung - cytology; Lung - metabolism; Lung - virology; Male; Microbiology; Microbiology/Immunity to Infections; Mink; Mortality; Mustela; Mutation - genetics; Nonstructural proteins; Orthomyxoviridae Infections - genetics; Orthomyxoviridae Infections - pathology; Orthomyxoviridae Infections - virology; Pandemics; Pathogenicity; Pathogens; Pathology; Replication; Respiratory Medicine/Respiratory Infections; Viral Nonstructural Proteins - genetics; Viral Nonstructural Proteins - metabolism; Virology; Virology/Animal Models of Infection; Virology/Effects of Virus Infection on Host Gene Expression; Virology/Emerging Viral Diseases; Virology/Host Antiviral Responses; Virology/Virulence Factors and Mechanisms; Virulence; Virulence (Microbiology); Virulence - physiology; Viruses; Vietnam