Immune regulation of the gut-brain axis and lung-brain axis involved in ischemic stroke

• Published in: Neural regeneration research Vol. 19; no. 3; pp. 519 - 528
• Main Authors: Xie, Xiaodi, Wang, Lei, Dong, Shanshan, Ge, ShanChun, Zhu, Ting
• Format: Journal Article
• Language: English
• Published: Mumbai Wolters Kluwer India Pvt. Ltd 01.03.2024; Medknow Publications & Media Pvt. Ltd; Institute of Neuroregeneration & Neurorehabilitation,Department of Pathophysiology,School of Basic Medicine,Qingdao University,Qingdao,Shandong Province,China%Institute of Neuroregeneration & Neurorehabilitation,Department of Pathophysiology,School of Basic Medicine,Qingdao University,Qingdao,Shandong Province,China; School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing,Jiangsu Province,China%Institute of Neuroregeneration & Neurorehabilitation,Department of Pathophysiology,School of Basic Medicine,Qingdao University,Qingdao,Shandong Province,China; Department of Rehabilitation Medicine,The Affiliated Hospital of Qingdao University,Qingdao,Shandong Province,China%School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing,Jiangsu Province,China; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: enteric glia cells; gut microbiota; gut-brain axis; immune response; inflammation; ischemic stroke; lung-brain axis; microglia; Gut-brain axis; Immune response; Ischemia; Lungs; Review; lung-brain axis; immune response; inflammation; enteric glia cells; microglia; gut microbiota; ischemic stroke; gut-brain axis

Local ischemia often causes a series of inflammatory reactions when both brain immune cells and the peripheral immune response are activated. In the human body, the gut and lung are regarded as the key reactional targets that are initiated by brain ischemic attacks. Mucosal microorganisms play an im...