Inhibition of Aldose Reductase Prevents Experimental Allergic Airway Inflammation in Mice - Yadav, Umesh C. S.; Ramana, Kota V.; Aguilera-Aguirre, Leopoldo; Boldogh, Istvan; Boulares, Hamid A.; Srivastava, Satish K. (PloS one, 2009)
Keywords: Aldehyde reductase; Aldehyde Reductase - antagonists & inhibitors; Aldose reductase; Allergens; Allergies; Alveoli; Ambrosia artemisiifolia; Analysis; Animal models; Animals; Apoptosis; Asthma; Asthma - etiology; Asthma - prevention & control; Biochemistry; Bioindicators; Bronchus; Cell Cycle Proteins - antagonists & inhibitors; Cell Cycle Proteins - metabolism; Cell death; Chemokines; Chemokines - antagonists & inhibitors; Chemokines - biosynthesis; Clinical trials; Complications; Cyclooxygenase-2; Cytokines; Cytokines - antagonists & inhibitors; Cytokines - biosynthesis; Cytotoxicity; Diabetes; Diabetes mellitus; Diabetic neuropathy; Drugs; Endotoxins; Enzyme Inhibitors - pharmacology; Enzyme Inhibitors - therapeutic use; Eosinophils; Epithelial cells; Health aspects; Health sciences; Homeostasis; Hypersensitivity; Hypersensitivity - complications; Immunology; Immunology/Allergy and Hypersensitivity; Infiltration; Inflammation; Inflammation Mediators - antagonists & inhibitors; Inflammation Mediators - metabolism; Inhibition; Inhibitors; Interleukin 6; Interleukin 8; Kinases; Leukocytes (eosinophilic); Lipids; Medical research; Mice; Mice, Inbred BALB C; Molecular biology; Monosaccharides; Morbidity; Mucin; NF-kappa B - antagonists & inhibitors; NF-kappa B - metabolism; NF-κB protein; Nitric oxide; Nitric-oxide synthase; Oxidative stress; Oxidizing agents; Pathogenesis; Pollen; Polyols; Prevention; Respiratory Medicine/Asthma; Respiratory Medicine/Environmental and Occupational Lung Diseases; Respiratory system agents; Respiratory tract; Respiratory tract diseases; Rodents; Studies; Transcription factors; Louisiana; United States--US; Texas