Why use a connectivity-based approach to study stroke and recovery of function?

• Published in: NeuroImage (Orlando, Fla.) Vol. 62; no. 4; pp. 2271 - 2280
• Main Authors: Carter, Alex R., Shulman, Gordon L., Corbetta, Maurizio
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2012; Elsevier Limited
• Subjects: Behavior; Brain - pathology; Brain - physiopathology; Brain Mapping - methods; Connectivity; fMRI; Humans; Inter-hemispheric; Magnetic Resonance Imaging; Medical imaging; Neural Pathways - pathology; Neural Pathways - physiopathology; Patients; Recovery; Recovery of Function - physiology; Rest - physiology; Resting state; Stroke; Stroke - complications; Stroke - pathology; Stroke - physiopathology; Studies; fMRI; Connectivity; Stroke; Inter-hemispheric; Resting state; Recovery

The brain is organized into a set of widely distributed networks. Therefore, although structural damage from stroke is focal, remote dysfunction can occur in regions connected to the area of lesion. Historically, neuroscience has focused on local processing due in part to the absence of tools to stu...