MLSA phylogeny and antimicrobial susceptibility of clinical Nocardia isolates: a multicenter retrospective study in China

• Published in: BMC microbiology Vol. 21; no. 1; pp. 342 - 11
• Main Authors: Wei, Ming, Xu, Xinmin, Yang, Jingxian, Wang, Peng, Liu, Yongzhe, Wang, Shuai, Yang, Chunxia, Gu, Li
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.12.2021; BioMed Central; BMC
• Subjects: Actinomycetales infections; Adult; Aged; Aged, 80 and over; Amikacin; Analysis; Anti-Bacterial Agents - pharmacology; Antibiotics; Antiinfectives and antibacterials; Antimicrobial agents; Antimicrobial susceptibility; China; Ciprofloxacin; Clarithromycin; Clinical medicine; Dosage and administration; Drug Resistance, Bacterial - drug effects; Drug Resistance, Bacterial - genetics; Drug susceptibility pattern; Empirical analysis; Epidemiology; Female; Geographical distribution; Humans; Hybridization; Identification; Imipenem; Infections; Laboratories; Linezolid; Low resistance; Male; Microbial Sensitivity Tests; Middle Aged; MLSA; Multilocus Sequence Typing; Nocardia; Nocardia - classification; Nocardia - drug effects; Nocardia - genetics; Nocardia - isolation & purification; Nocardia Infections - microbiology; Nocardiosis; Phylogenetics; Phylogeny; Prevention; Retrospective Studies; Risk factors; Sequence analysis; Sulfamethoxazole; Susceptibility; Tertiary Care Centers; Trimethoprim; Young Adult; China; Beijing China; Antimicrobial susceptibility; MLSA; Nocardia; Drug susceptibility pattern; China

With the increase of detection rate and long treatment period, nocardiosis has become a noticeable problem in China. However, there are limited large-scale studies on the epidemiology and antimicrobial susceptibility profiles of clinical Nocardia spp. in China. The present study aimed to explore the...