Development and Clinical Application of an Enzyme-Linked Immunosorbent Assay for Oxidized High-Density Lipoprotein

• Published in: Journal of Atherosclerosis and Thrombosis Vol. 28; no. 7; pp. 703 - 715
• Main Authors: Sumida, Mizuki, Kanno, Kotaro, Okada, Takeshi, Ohama, Tohru, Inui, Hiroyasu, Koseki, Masahiro, Nishida, Makoto, Masuda, Daisaku, Katayama, Yuki, Saga, Ayami, Yamashita, Shizuya, Sakata, Yasushi
• Format: Journal Article
• Language: English
• Published: Japan Atherosclerosis Society 01.07.2021
• Subjects: Apolipoproteins; Familial hypercholesterolemia; HDL; Original; Oxidized lipids; Phospholipids
• ISSN: 1340-3478; 1880-3873; 1880-3873
• DOI: 10.5551/jat.56887

Aims: HDL particles have various anti-atherogenic functions, whereas HDL from atherosclerotic patients was demonstrated to be dysfunctional. One possible mechanism for the formation of dysfunctional HDL is the oxidation of its components. However, oxidized HDLs (Ox-HDLs) remain to be well investigat...