Tuberculosis and diabetes mellitus: convergence of two epidemics

• Published in: The Lancet infectious diseases Vol. 9; no. 12; pp. 737 - 746
• Main Authors: Dooley, Kelly E, Chaisson, Richard E
• Format: Journal Article
• Language: English
• Published: London Elsevier Ltd 01.12.2009; Lancet Publishing Group; Elsevier Limited
• Subjects: Anti-Bacterial Agents - therapeutic use; Bacterial diseases; Biological and medical sciences; Convergence; Diabetes Complications - complications; Diabetes Complications - mortality; Diabetes Complications - physiopathology; Diabetes mellitus; Diabetes. Impaired glucose tolerance; Disease Outbreaks; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Epidemics; Epidemiology; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; Global Health; Glucose tolerance; Human bacterial diseases; Human immunodeficiency virus; Humans; Hypoglycemic Agents - therapeutic use; Infection; Infectious Disease; Infectious diseases; Living conditions; Male; Malnutrition; Medical sciences; Mycobacterium; Obesity; Pharmacokinetics; Prevalence; Reviews; Risk factors; Tuberculosis; Tuberculosis - complications; Tuberculosis - mortality; Tuberculosis - physiopathology; Tuberculosis and atypical mycobacterial infections; Endocrinopathy; Infection; Epidemic; Tuberculosis; Diabetes mellitus; Bacteriosis; Mycobacterial infection

The link between diabetes mellitus and tuberculosis has been recognised for centuries. In recent decades, tuberculosis incidence has declined in high-income countries, but incidence remains high in countries that have high rates of infection with HIV, high prevalence of malnutrition and crowded livi...