Dynamic regulation and functions of mRNA m6A modification

• Published in: Cancer cell international Vol. 22; no. 1; pp. 48 - 12
• Main Authors: Wang, Shanshan, Lv, Wei, Li, Tao, Zhang, Shubing, Wang, Huihui, Li, Xuemei, Wang, Lianzi, Ma, Dongyue, Zang, Yan, Shen, Jilong, Xu, Yuanhong, Wei, Wei
• Format: Journal Article
• Language: English
• Published: England BioMed Central 29.01.2022; BMC
• Subjects: Binding sites; Cancer; Cell growth; Enzymes; Gene expression; Homeostasis; Leukemia; Localization; m6A; Mechanism; Metabolism; Metastases; Metastasis; mRNA metabolism; N6-methyladenosine; Proteins; Review; RNA modification; Tumorigenesis; Tumors; Writers; m6A; Gene expression; mRNA metabolism; Mechanism

N 6 -Methyladenosine (m6A), the most abundant internal modification associated with eukaryotic mRNAs, has emerged as a dynamic regulatory mechanism controlling the expression of genes involved in many physiological activities by affecting various steps of mRNA metabolism, including splicing, export,...