Autophagy in the control and pathogenesis of parasitic infections

• Published in: Cell & bioscience Vol. 10; no. 1; p. 101
• Main Authors: Ghartey-Kwansah, George, Adu-Nti, Frank, Aboagye, Benjamin, Ankobil, Amandus, Essuman, Edward Eyipe, Opoku, Yeboah Kwaku, Abokyi, Samuel, Abu, Emmanuel Kwasi, Boampong, Johnson Nyarko
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 05.09.2020; BioMed Central; BMC
• Subjects: Apoptosis; Autophagosome; Autophagy; Defense mechanisms; Drug development; Health aspects; Host-parasite interactions; Immune clearance; Immunosuppressive agents; Infections; Initiation complex; Kinases; PAAR; Parasites; Parasitic diseases; Parasitophorous vacuole; Pathogenesis; Pathogens; Phagocytosis; Proteins; Review; Signal transduction; Toll-like receptors; Xenophagy; Xenophagy; Autophagosome; Autophagy; PAAR; Parasitophorous vacuole

Autophagy has a crucial role in the defense against parasites. The interplay existing between host autophagy and parasites has varied outcomes due to the kind of host cell and microorganism. The presence of autophagic compartments disrupt a significant number of pathogens and are further cleared by...