Quercetin manipulates the expression of genes involved in the reactive oxygen species (ROS) process in chicken heterophils

• Published in: Journal of Veterinary Medical Science Vol. 80; no. 8; pp. 1204 - 1211
• Main Authors: CHUAMMITRI, Phongsakorn, WONGSAWAN, Kanreuthai, NAMBOOPPHA, Boondarika, PHOTICHAI, Kornravee
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2018; Japan Science and Technology Agency; The Japanese Society of Veterinary Science
• Subjects: Animals; Antioxidants; Antioxidants - pharmacology; Apoptosis; Cell death; chicken; Chickens; CYBB protein; Flow cytometry; Gene expression; Gene Expression Regulation; Gene regulation; Genes; Genetic engineering; heterophil; Immunology; Inflammation; Interleukin 6; Intracellular; Leukocytes (neutrophilic); Mcl-1 protein; MCL1 gene; Phorbol esters; Polymerase chain reaction; Quercetin; Quercetin - pharmacology; Rac2 protein; Reactive oxygen species; Reactive Oxygen Species - metabolism; Stimulants; Superoxide dismutase; quercetin; chicken; heterophil; gene expression; reactive oxygen species

Chicken heterophils generate reactive oxygen species (ROS) molecules to defend against invading pathogens. The present study examined effects of quercetin on chicken heterophils. Heterophils were stimulated with PBS, 50 µM quercetin (QH), PMA or Escherichia coli (EC) and the resulting intracellular...