Functional consequences of pre- and postsynaptic expression of synaptic plasticity

• Published in: Philosophical transactions of the Royal Society of London. Series B. Biological sciences Vol. 372; no. 1715; p. 20160153
• Main Authors: Costa, Rui Ponte, Mizusaki, Beatriz E. P., Sjöström, P. Jesper, van Rossum, Mark C. W.
• Format: Journal Article
• Language: English
• Published: England The Royal Society 05.03.2017; The Royal Society Publishing
• Subjects: Animals; Functional plasticity; Hebbian Plasticity; Homeostasis; Homeostatic plasticity; Homoeostatic Plasticity; Humans; Loci; Long-Term Potentiation; Memory; Models, Neurological; Neuronal Plasticity; Plasticity; Reaction Time; Review; Sensation; Sensory perception; Spike-Timing-Dependent Plasticity; Synaptic Plasticity; Synaptic Release; synaptic release; synaptic plasticity; Hebbian plasticity; spike-timing-dependent plasticity; homoeostatic plasticity; long-term potentiation

Growing experimental evidence shows that both homeostatic and Hebbian synaptic plasticity can be expressed presynaptically as well as postsynaptically. In this review, we start by discussing this evidence and methods used to determine expression loci. Next, we discuss the functional consequences of...