Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis

To the Editor: Atopic dermatitis (AD) is the most common inflammatory skin disease, affecting up to 20% of children in the United States, and is characterized by an increased susceptibility to cutaneous infections.1,2 One in 10 subjects with AD has difficulty clearing cutaneous infections with a hos...

Full description

Saved in:

Bibliographic Details
Published in	Journal of allergy and clinical immunology Vol. 128; no. 1; pp. 242 - 246.e5
Main Authors	De Benedetto, Anna, Slifka, Mark K., Rafaels, Nicholas M., Kuo, I-Hsin, Georas, Steve N., Boguniewicz, Mark, Hata, Tissa, Schneider, Lynda C., Hanifin, Jon M., Gallo, Richard L., Johnson, David C., Barnes, Kathleen C., Leung, Donald Y.M., Beck, Lisa A.
Format	Journal Article
Language	English
Published	New York, NY Mosby, Inc 01.07.2011 Elsevier Elsevier Limited
Subjects	Adult Allergic diseases Allergy and Immunology Biological and medical sciences Cells, Cultured Claudin-1 Dermatitis, Atopic - complications Dermatitis, Atopic - genetics Dermatitis, Atopic - microbiology Female Fundamental and applied biological sciences. Psychology Fundamental immunology Genetic Predisposition to Disease Haplotypes Humans Immunopathology Infections Kaposi Varicelliform Eruption - genetics Keratinocytes - metabolism Male Medical sciences Membrane Proteins - genetics Mutation Permeability Polymorphism, Single Nucleotide Proteins Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Skin allergic diseases. Stinging insect allergies Tight Junctions - metabolism Young Adult Claudin 1 Allergy Immunopathology Skin disease Herpesviridae Alphaherpesvirinae Atopy Virus Infection Sensitivity Immunology Atopic dermatitis Human herpesvirus 1
Online Access	Get full text

Cover

Loading…

Abstract	To the Editor: Atopic dermatitis (AD) is the most common inflammatory skin disease, affecting up to 20% of children in the United States, and is characterized by an increased susceptibility to cutaneous infections.1,2 One in 10 subjects with AD has difficulty clearing cutaneous infections with a host of viruses including herpes simplex, vaccinia, human papilloma, and/or molluscum contagiosum.1 This typically manifests as more extensive cutaneous and sometimes systemic disease and/or resistance to standard therapies.
AbstractList	To the Editor: Atopic dermatitis (AD) is the most common inflammatory skin disease, affecting up to 20% of children in the United States, and is characterized by an increased susceptibility to cutaneous infections.1,2 One in 10 subjects with AD has difficulty clearing cutaneous infections with a host of viruses including herpes simplex, vaccinia, human papilloma, and/or molluscum contagiosum.1 This typically manifests as more extensive cutaneous and sometimes systemic disease and/or resistance to standard therapies.
Author	Schneider, Lynda C. Boguniewicz, Mark Georas, Steve N. Johnson, David C. Leung, Donald Y.M. Hata, Tissa Kuo, I-Hsin Beck, Lisa A. De Benedetto, Anna Gallo, Richard L. Rafaels, Nicholas M. Slifka, Mark K. Hanifin, Jon M. Barnes, Kathleen C.
Author_xml	– sequence: 1 givenname: Anna surname: De Benedetto fullname: De Benedetto, Anna organization: Department of Dermatology, University of Rochester Medical Center, NY – sequence: 2 givenname: Mark K. surname: Slifka fullname: Slifka, Mark K. organization: Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Ore – sequence: 3 givenname: Nicholas M. surname: Rafaels fullname: Rafaels, Nicholas M. organization: Johns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, Md – sequence: 4 givenname: I-Hsin surname: Kuo fullname: Kuo, I-Hsin organization: Department of Dermatology, University of Rochester Medical Center, NY – sequence: 5 givenname: Steve N. surname: Georas fullname: Georas, Steve N. organization: Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, NY – sequence: 6 givenname: Mark surname: Boguniewicz fullname: Boguniewicz, Mark organization: Department of Pediatrics, National Jewish Health, Denver, Colo – sequence: 7 givenname: Tissa surname: Hata fullname: Hata, Tissa organization: Division of Dermatology, University of California San Diego, Calif – sequence: 8 givenname: Lynda C. surname: Schneider fullname: Schneider, Lynda C. organization: Division of Immunology, Children’s Hospital Boston, Mass – sequence: 9 givenname: Jon M. surname: Hanifin fullname: Hanifin, Jon M. organization: Department of Dermatology, Oregon Health and Science University, Beaverton, Ore – sequence: 10 givenname: Richard L. surname: Gallo fullname: Gallo, Richard L. organization: Division of Dermatology, University of California San Diego, Calif – sequence: 11 givenname: David C. surname: Johnson fullname: Johnson, David C. organization: Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Ore – sequence: 12 givenname: Kathleen C. surname: Barnes fullname: Barnes, Kathleen C. organization: Johns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, Md – sequence: 13 givenname: Donald Y.M. surname: Leung fullname: Leung, Donald Y.M. organization: Department of Pediatrics, National Jewish Health, Denver, Colo – sequence: 14 givenname: Lisa A. surname: Beck fullname: Beck, Lisa A. email: Lisa_Beck@URMC.Rochester.edu organization: Department of Dermatology, University of Rochester Medical Center, NY
BackLink	http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24346449$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/21489616$$D View this record in MEDLINE/PubMed
BookMark	eNqFkt2L1DAUxYOsuLOr_4APEhDxqWPSZtJERJDFL1gQ_HgOaXrL3rFfJu3i_PfeMrMMDLj7VAK_c8o591yws37ogbHnUqylkPrNdr31Ade5kHIt8rWQ6hFbSWHLTJt8c8ZWQliZ6VLZc3aR0lbQuzD2CTvPpTJWS71i7Xeo5zDh0CeOPQ-tn2vsM8k7v-PQ3_g-AE9zCjBOWGGL045PA7-BOELiCbuxhb_8FuOcuCSHBo5mfhpGDLyG2PkJJ0xP2ePGtwmeHb6X7Nenjz-vvmTX3z5_vfpwnQWt5ZQZq5SlgI0AZaX1oaqll7qqQlFYZYKSUgSjrW4aCpoHqXThrYdgQ7lZoEv2eu87xuHPDGlyHVKCtvU9DHNyxhRCmdzKh8mSirK6FES-PCG3wxx7iuHkRpVGKSqeqBcHaq46qN0YsfNx5-4KJ-DVAfAp-LaJVDCmI6cKpSk9cWbPhTikFKFxASe_VDtFj62Twi0bcFu3bMAtG3Aid7QBkuYn0jv3e0Xv9iKgu9wiRJcCAh2_xkgndfWA98vfn8hDiz1Swt-wg3SsyiUSuB_LMpdh0iVFXurF4O3_DR76-z-BzfFd
CODEN	JACIBY
CitedBy_id	crossref_primary_10_1007_s12016_022_08953_x crossref_primary_10_1095_biolreprod_114_122887 crossref_primary_10_4168_aard_2013_1_1_20 crossref_primary_10_3390_cells11081337 crossref_primary_10_1016_j_jaci_2016_07_012 crossref_primary_10_3390_ijms17081234 crossref_primary_10_4161_21688370_2014_974451 crossref_primary_10_1111_all_14762 crossref_primary_10_1016_j_jid_2019_06_145 crossref_primary_10_3390_ijms21207607 crossref_primary_10_1111_febs_13904 crossref_primary_10_1007_s00424_016_1903_9 crossref_primary_10_1016_j_coi_2011_09_007 crossref_primary_10_1007_s13671_011_0003_5 crossref_primary_10_1128_jvi_00262_23 crossref_primary_10_1186_s13223_016_0158_5 crossref_primary_10_1111_bjd_12382 crossref_primary_10_1016_j_jdermsci_2021_10_002 crossref_primary_10_1016_j_antiviral_2013_02_010 crossref_primary_10_1016_j_jaci_2014_05_049 crossref_primary_10_1111_bjd_18643 crossref_primary_10_26442_20751753_2024_8_202876 crossref_primary_10_1111_jdv_16090 crossref_primary_10_1016_j_cyto_2014_11_023 crossref_primary_10_1016_j_aller_2017_07_002 crossref_primary_10_1155_2011_769890 crossref_primary_10_1016_j_anai_2020_05_016 crossref_primary_10_1016_j_jaci_2023_08_024 crossref_primary_10_1093_infdis_jiz095 crossref_primary_10_1016_j_micpath_2021_105012 crossref_primary_10_1093_cid_ciae225 crossref_primary_10_1016_j_xjidi_2022_100151 crossref_primary_10_2217_fmb_2017_0081 crossref_primary_10_1016_j_xjidi_2021_100018 crossref_primary_10_1111_exd_12055 crossref_primary_10_3390_ijms19103166 crossref_primary_10_1111_all_14853 crossref_primary_10_3390_toxins9010003 crossref_primary_10_1016_j_jaci_2011_11_016 crossref_primary_10_1111_j_1600_065X_2011_01027_x crossref_primary_10_1016_j_jaci_2014_02_017 crossref_primary_10_1016_j_jid_2023_03_1656 crossref_primary_10_3390_pharmaceutics12070684 crossref_primary_10_1016_j_jaci_2018_08_022 crossref_primary_10_1172_JCI124608 crossref_primary_10_1007_s12016_015_8508_5 crossref_primary_10_1016_j_jdermsci_2018_09_006 crossref_primary_10_1111_1346_8138_14792 crossref_primary_10_1007_s11882_014_0433_9 crossref_primary_10_5124_jkma_2014_57_3_218 crossref_primary_10_3390_ijms242417333 crossref_primary_10_3390_jcm12041538 crossref_primary_10_1111_jcmm_13311 crossref_primary_10_1128_jvi_00864_22 crossref_primary_10_1016_j_jaci_2017_09_048 crossref_primary_10_1152_ajplung_00104_2020 crossref_primary_10_1590_abd1806_4841_20164412 crossref_primary_10_1016_j_jaci_2020_02_021 crossref_primary_10_3906_vet_1507_26 crossref_primary_10_1016_j_jaci_2018_01_007 crossref_primary_10_1186_s13148_019_0714_1 crossref_primary_10_2332_allergolint_13_RAI_0564 crossref_primary_10_3390_ijms19113549 crossref_primary_10_3389_fmicb_2023_1192956 crossref_primary_10_1124_mol_118_112730 crossref_primary_10_3390_ijms241512367 crossref_primary_10_1586_edm_12_19 crossref_primary_10_1016_j_alit_2022_05_003 crossref_primary_10_1016_j_xjidi_2022_100131 crossref_primary_10_1016_j_jaci_2012_06_019 crossref_primary_10_1128_spectrum_01684_23 crossref_primary_10_1159_000513055 crossref_primary_10_1002_JLB_5MR0120_230R crossref_primary_10_1111_jcmm_13763 crossref_primary_10_1007_s11033_021_07081_7 crossref_primary_10_1016_j_jdermsci_2021_04_007 crossref_primary_10_1007_s12016_019_08768_3 crossref_primary_10_1136_bmjopen_2014_006627 crossref_primary_10_1016_j_drudis_2012_02_014 crossref_primary_10_1016_j_jaci_2012_12_1563 crossref_primary_10_1111_bjd_16934
Cites_doi	10.1099/vir.0.19226-0 10.1167/iovs.08-3046 10.1007/s00439-006-0182-5 10.1083/jcb.200110122 10.1167/iovs.09-3820 10.1086/381000 10.1016/S0076-6879(06)10003-8 10.1016/j.jaci.2009.05.020 10.1111/j.1398-9995.2004.00569.x 10.1006/meth.2001.1262 10.1034/j.1600-0625.2001.100102.x 10.1016/j.jaci.2009.07.013 10.2741/3276 10.1126/science.280.5369.1618 10.1016/j.jaci.2009.11.027 10.1126/science.1069424 10.1109/TSMC.1979.4310076 10.1016/j.jaci.2009.07.034 10.1038/sj.jid.5700865 10.1016/j.jaci.2010.10.018
ContentType	Journal Article
Copyright	2011 American Academy of Allergy, Asthma & Immunology American Academy of Allergy, Asthma & Immunology 2015 INIST-CNRS Copyright Elsevier Limited Jul 2011
Copyright_xml	– notice: 2011 American Academy of Allergy, Asthma & Immunology – notice: American Academy of Allergy, Asthma & Immunology – notice: 2015 INIST-CNRS – notice: Copyright Elsevier Limited Jul 2011
DBID	AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 7SS 7T5 H94 K9. NAPCQ 7X8
DOI	10.1016/j.jaci.2011.02.014
DatabaseName	CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Entomology Abstracts (Full archive) Immunology Abstracts AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium MEDLINE - Academic
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Entomology Abstracts AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium Immunology Abstracts MEDLINE - Academic
DatabaseTitleList	Entomology Abstracts
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Medicine
EISSN	1097-6825
EndPage	246.e5
ExternalDocumentID	3382327851 21489616 24346449 10_1016_j_jaci_2011_02_014 S0091674911002764 1_s2_0_S0091674911002764
Genre	Letter Research Support, U.S. Gov't, P.H.S Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural
GrantInformation_xml	– fundername: National Institutes of Health/National Institute of Allergy and Infectious Diseases – fundername: Atopic Dermatitis Research Network grantid: HHSN272201000020C and HHSN272201000017C – fundername: National Institutes of Health – fundername: DHHS/PHS/NIH – fundername: National Eczema Association – fundername: Oregon National Primate Research Center grantid: RR000163 – fundername: National Institutes of Health/National Institute of Allergy and Infectious Diseases, the National Eczema Association, and Centocor Inc – fundername: Atopic Dermatitis and Vaccinia Network NIH/NIAID grantid: N01 AI40029 and N01 AI40033 – fundername: Mary Beryl Patch Turnbull Scholar Program – fundername: Astellas and Novartis – fundername: NIAID NIH HHS grantid: HHSN266200400029C – fundername: NCRR NIH HHS grantid: K01 RR000163 – fundername: NIAID NIH HHS grantid: N01 AI40033 – fundername: NIAID NIH HHS grantid: HHSN272201000020C – fundername: NIAID NIH HHS grantid: N01 AI040033 – fundername: NIAID NIH HHS grantid: HHSN272201000020I – fundername: NIAID NIH HHS grantid: N01 AI040029 – fundername: NIAID NIH HHS grantid: HHSN272201000017C – fundername: NCRR NIH HHS grantid: P51 RR000163
GroupedDBID	--- --K --M -~X .1- .55 .FO .GJ .XZ .~1 0R~ 1B1 1P~ 1RT 1~. 1~5 354 3O- 4.4 457 4G. 53G 5GY 5RE 5VS 7-5 71M 8F7 8FE 8FH 8P~ 9JM AAAJQ AABNK AAEDT AAEDW AAFWJ AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AARKO AATTM AAXKI AAXUO AAYWO ABBQC ABFNM ABJNI ABLJU ABMAC ABMZM ABOCM ABWVN ABXDB ACDAQ ACGFO ACGFS ACIEU ACPRK ACRLP ACRPL ACVFH ADBBV ADCNI ADEZE ADFRT ADMUD ADNMO ADVLN ADXHL AEBSH AEIPS AEKER AENEX AEUPX AFFNX AFJKZ AFPUW AFRAH AFRHN AFTJW AFXIZ AGCQF AGEKW AGHFR AGQPQ AGUBO AGYEJ AHHHB AHMBA AIEXJ AIGII AIIUN AIKHN AITUG AJRQY AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU ANZVX APXCP ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV BPHCQ BVXVI C45 CAG CJTIS COF CS3 DU5 EBS EFJIC EFKBS EJD EO8 EO9 EP2 EP3 EX3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HDU HMK HMO HVGLF HZ~ IHE J1W J5H K-O KOM L7B LK8 LUGTX M27 M41 MO0 N4W N9A O-L O9- O9~ OAUVE OBH ODZKP OHH OHT OK0 OK1 OVD OZT P-8 P-9 P2P PC. PQQKQ PROAC Q38 R2- ROL RPZ SAE SCC SDF SDG SDP SEL SES SEW SJN SPCBC SSH SSI SSZ T5K TEORI TWZ UGJ UNMZH UV1 WH7 WOW WUQ X7M XFW YOC YQI YQJ Z5R ZGI ZXP ZY1 ~02 ~G- ~KM AACTN RIG AAYXX AGRNS CITATION IQODW CGR CUY CVF ECM EIF NPM 7SS 7T5 H94 K9. NAPCQ 7X8
ID	FETCH-LOGICAL-c661t-89449016f0e4919acbd1a16bbc33948c4110c8696ff6822c1463a9aec9c75bc33
IEDL.DBID	.~1
ISSN	0091-6749 1097-6825
IngestDate	Fri Jul 11 00:20:42 EDT 2025 Fri Jul 11 08:33:17 EDT 2025 Wed Aug 13 06:10:50 EDT 2025 Mon Jul 21 06:04:06 EDT 2025 Mon Jul 21 09:17:38 EDT 2025 Tue Jul 01 04:32:06 EDT 2025 Thu Apr 24 23:06:11 EDT 2025 Sun Apr 06 06:53:47 EDT 2025 Wed Apr 02 07:27:20 EDT 2025 Tue Aug 26 16:36:14 EDT 2025
IsDoiOpenAccess	false
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	1
Keywords	Claudin 1 Allergy Immunopathology Skin disease Herpesviridae Alphaherpesvirinae Atopy Virus Infection Sensitivity Immunology Atopic dermatitis Human herpesvirus 1
Language	English
License	https://www.elsevier.com/tdm/userlicense/1.0 CC BY 4.0
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c661t-89449016f0e4919acbd1a16bbc33948c4110c8696ff6822c1463a9aec9c75bc33
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Article-2 ObjectType-Correspondence-1 content type line 23 ObjectType-Feature-1
OpenAccessLink	http://www.jacionline.org/article/S0091674911002764/pdf
PMID	21489616
PQID	1547844097
PQPubID	105664
PageCount	5
ParticipantIDs	proquest_miscellaneous_883048291 proquest_miscellaneous_874899670 proquest_journals_1547844097 pubmed_primary_21489616 pascalfrancis_primary_24346449 crossref_citationtrail_10_1016_j_jaci_2011_02_014 crossref_primary_10_1016_j_jaci_2011_02_014 elsevier_sciencedirect_doi_10_1016_j_jaci_2011_02_014 elsevier_clinicalkeyesjournals_1_s2_0_S0091674911002764 elsevier_clinicalkey_doi_10_1016_j_jaci_2011_02_014
ProviderPackageCode	CITATION AAYXX
PublicationCentury	2000
PublicationDate	2011-07-01
PublicationDateYYYYMMDD	2011-07-01
PublicationDate_xml	– month: 07 year: 2011 text: 2011-07-01 day: 01
PublicationDecade	2010
PublicationPlace	New York, NY
PublicationPlace_xml	– name: New York, NY – name: United States – name: St. Louis
PublicationTitle	Journal of allergy and clinical immunology
PublicationTitleAlternate	J Allergy Clin Immunol
PublicationYear	2011
Publisher	Mosby, Inc Elsevier Elsevier Limited
Publisher_xml	– name: Mosby, Inc – name: Elsevier – name: Elsevier Limited
References	Gonzalez-Mariscal, Garay, Lechuga (bib8) 2009; 14 Boguniewicz, Leung (bib2) 2010; 125 Gao, Rafaels, Hand, Murray, Boguniewicz, Hata (bib4) 2009; 124 De Benedetto, Rafaels, McGirt, Ivanov, Georas, Cheadle (bib6) 2011; 127 Geraghty, Krummenacher, Cohen, Eisenberg, Spear (bib9) 1998; 280 Schelhaas, Jansen, Haase, Knebel-Morsdorf (bib10) 2003; 84 O’Regan, Sandilands, McLean, Irvine (bib3) 2009; 124 Shimazaki, Higa, Kato, Satake (bib11) 2009; 50 Beck, Boguniewicz, Hata, Schneider, Hanifin, Gallo (bib1) 2009; 124 Niessen (bib5) 2007; 127 Furuse, Hata, Furuse, Yoshida, Haratake, Sugitani (bib7) 2002; 156 Yoshida, Ban, Kinoshita (bib12) 2009; 50 Hanifin (10.1016/j.jaci.2011.02.014_bib18) 2001; 10 Gao (10.1016/j.jaci.2011.02.014_bib4) 2009; 124 Howie (10.1016/j.jaci.2011.02.014_bib20) 2006; 120 Fan (10.1016/j.jaci.2011.02.014_bib22) 2006; 410 Boguniewicz (10.1016/j.jaci.2011.02.014_bib2) 2010; 125 Gonzalez-Mariscal (10.1016/j.jaci.2011.02.014_bib8) 2009; 14 Geraghty (10.1016/j.jaci.2011.02.014_bib9) 1998; 280 Gabriel (10.1016/j.jaci.2011.02.014_bib21) 2002; 296 Livak (10.1016/j.jaci.2011.02.014_bib15) 2001; 25 Carlson (10.1016/j.jaci.2011.02.014_bib19) 2004; 74 Eichenfield (10.1016/j.jaci.2011.02.014_bib17) 2004; 59 O’Regan (10.1016/j.jaci.2011.02.014_bib3) 2009; 124 Yoshida (10.1016/j.jaci.2011.02.014_bib12) 2009; 50 Shimazaki (10.1016/j.jaci.2011.02.014_bib11) 2009; 50 Otsu (10.1016/j.jaci.2011.02.014_bib14) 1979; 9 De Benedetto (10.1016/j.jaci.2011.02.014_bib6) 2011; 127 Beck (10.1016/j.jaci.2011.02.014_bib1) 2009; 124 De Benedetto (10.1016/j.jaci.2011.02.014_bib13) 2011; 127 Furuse (10.1016/j.jaci.2011.02.014_bib7) 2002; 156 Schelhaas (10.1016/j.jaci.2011.02.014_bib10) 2003; 84 Niessen (10.1016/j.jaci.2011.02.014_bib5) 2007; 127 Beck (10.1016/j.jaci.2011.02.014_bib16) 2009; 124 J Allergy Clin Immunol. 2011 Oct; 128(4):903
References_xml	– volume: 156 start-page: 1099 year: 2002 end-page: 1111 ident: bib7 article-title: Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice publication-title: J Cell Biol – volume: 127 start-page: 773 year: 2011 end-page: 786 ident: bib6 article-title: Tight junctions defects in patients with atopic dermatitis publication-title: J Allergy Clin Immunol – volume: 124 start-page: R2 year: 2009 end-page: R6 ident: bib3 article-title: Filaggrin in atopic dermatitis publication-title: J Allergy Clin Immunol – volume: 125 start-page: 4 year: 2010 end-page: 13 ident: bib2 article-title: Recent insights into atopic dermatitis and implications for management of infectious complications publication-title: J Allergy Clin Immunol – volume: 14 start-page: 731 year: 2009 end-page: 768 ident: bib8 article-title: Virus interaction with the apical junctional complex publication-title: Front Biosci – volume: 50 start-page: 5672 year: 2009 end-page: 5680 ident: bib11 article-title: Barrier function of cultivated limbal and oral mucosal epithelial cell sheets publication-title: Invest Ophthalmol Vis Sci – volume: 50 start-page: 2103 year: 2009 end-page: 2108 ident: bib12 article-title: Tight junction transmembrane protein claudin subtype expression and distribution in human corneal and conjunctival epithelium publication-title: Invest Ophthalmol Vis Sci – volume: 124 start-page: 507 year: 2009 end-page: 513 ident: bib4 article-title: Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum publication-title: J Allergy Clin Immunol – volume: 124 start-page: 260 year: 2009 end-page: 269 ident: bib1 article-title: Phenotype of atopic dermatitis subjects with a history of eczema herpeticum publication-title: J Allergy Clin Immunol – volume: 280 start-page: 1618 year: 1998 end-page: 1620 ident: bib9 article-title: Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor publication-title: Science – volume: 127 start-page: 2525 year: 2007 end-page: 2532 ident: bib5 article-title: Tight junctions/adherens junctions: basic structure and function publication-title: J Invest Dermatol – volume: 84 start-page: 2473 year: 2003 end-page: 2484 ident: bib10 article-title: Herpes simplex virus type 1 exhibits a tropism for basal entry in polarized epithelial cells publication-title: J Gen Virol – volume: 84 start-page: 2473 year: 2003 ident: 10.1016/j.jaci.2011.02.014_bib10 article-title: Herpes simplex virus type 1 exhibits a tropism for basal entry in polarized epithelial cells publication-title: J Gen Virol doi: 10.1099/vir.0.19226-0 – volume: 50 start-page: 2103 year: 2009 ident: 10.1016/j.jaci.2011.02.014_bib12 article-title: Tight junction transmembrane protein claudin subtype expression and distribution in human corneal and conjunctival epithelium publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.08-3046 – volume: 120 start-page: 58 year: 2006 ident: 10.1016/j.jaci.2011.02.014_bib20 article-title: Efficient selection of tagging single-nucleotide polymorphisms in multiple populations publication-title: Hum Genet doi: 10.1007/s00439-006-0182-5 – volume: 156 start-page: 1099 year: 2002 ident: 10.1016/j.jaci.2011.02.014_bib7 article-title: Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice publication-title: J Cell Biol doi: 10.1083/jcb.200110122 – volume: 50 start-page: 5672 year: 2009 ident: 10.1016/j.jaci.2011.02.014_bib11 article-title: Barrier function of cultivated limbal and oral mucosal epithelial cell sheets publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.09-3820 – volume: 74 start-page: 106 year: 2004 ident: 10.1016/j.jaci.2011.02.014_bib19 article-title: Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium publication-title: Am J Hum Genet doi: 10.1086/381000 – volume: 410 start-page: 57 year: 2006 ident: 10.1016/j.jaci.2011.02.014_bib22 article-title: Illumina universal bead arrays publication-title: Methods Enzymol doi: 10.1016/S0076-6879(06)10003-8 – volume: 124 start-page: 260 year: 2009 ident: 10.1016/j.jaci.2011.02.014_bib1 article-title: Phenotype of atopic dermatitis subjects with a history of eczema herpeticum publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2009.05.020 – volume: 59 start-page: 86 issue: suppl 78 year: 2004 ident: 10.1016/j.jaci.2011.02.014_bib17 article-title: Consensus guidelines in diagnosis and treatment of atopic dermatitis publication-title: Allergy doi: 10.1111/j.1398-9995.2004.00569.x – volume: 25 start-page: 402 year: 2001 ident: 10.1016/j.jaci.2011.02.014_bib15 article-title: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method publication-title: Methods doi: 10.1006/meth.2001.1262 – volume: 10 start-page: 11 year: 2001 ident: 10.1016/j.jaci.2011.02.014_bib18 article-title: The Eczema Area and Severity Index (EASI): assessment of reliability in atopic dermatitis. EASI Evaluator Group publication-title: Exp Dermatol doi: 10.1034/j.1600-0625.2001.100102.x – volume: 124 start-page: R2 year: 2009 ident: 10.1016/j.jaci.2011.02.014_bib3 article-title: Filaggrin in atopic dermatitis publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2009.07.013 – volume: 14 start-page: 731 year: 2009 ident: 10.1016/j.jaci.2011.02.014_bib8 article-title: Virus interaction with the apical junctional complex publication-title: Front Biosci doi: 10.2741/3276 – volume: 280 start-page: 1618 year: 1998 ident: 10.1016/j.jaci.2011.02.014_bib9 article-title: Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor publication-title: Science doi: 10.1126/science.280.5369.1618 – volume: 125 start-page: 4 year: 2010 ident: 10.1016/j.jaci.2011.02.014_bib2 article-title: Recent insights into atopic dermatitis and implications for management of infectious complications publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2009.11.027 – volume: 296 start-page: 2225 year: 2002 ident: 10.1016/j.jaci.2011.02.014_bib21 article-title: The structure of haplotype blocks in the human genome publication-title: Science doi: 10.1126/science.1069424 – volume: 9 start-page: 62 year: 1979 ident: 10.1016/j.jaci.2011.02.014_bib14 article-title: A threshold selection method from gray-level histograms publication-title: IEEE Transactions on Systems, Man, and Cybernetics doi: 10.1109/TSMC.1979.4310076 – volume: 124 start-page: 507 year: 2009 ident: 10.1016/j.jaci.2011.02.014_bib4 article-title: Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2009.07.034 – volume: 127 start-page: 2525 year: 2007 ident: 10.1016/j.jaci.2011.02.014_bib5 article-title: Tight junctions/adherens junctions: basic structure and function publication-title: J Invest Dermatol doi: 10.1038/sj.jid.5700865 – volume: 127 start-page: 773 year: 2011 ident: 10.1016/j.jaci.2011.02.014_bib6 article-title: Tight junctions defects in patients with atopic dermatitis publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2010.10.018 – volume: 124 start-page: 260 year: 2009 ident: 10.1016/j.jaci.2011.02.014_bib16 article-title: Phenotype of atopic dermatitis subjects with a history of eczema herpeticum publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2009.05.020 – volume: 127 start-page: 773 year: 2011 ident: 10.1016/j.jaci.2011.02.014_bib13 article-title: Tight junctions defects in patients with atopic dermatitis publication-title: J Allergy Clin Immunol doi: 10.1016/j.jaci.2010.10.018 – reference: - J Allergy Clin Immunol. 2011 Oct; 128(4):903
SSID	ssj0009389
Score	2.3413942
Snippet	To the Editor: Atopic dermatitis (AD) is the most common inflammatory skin disease, affecting up to 20% of children in the United States, and is characterized...
SourceID	proquest pubmed pascalfrancis crossref elsevier
SourceType	Aggregation Database Index Database Enrichment Source Publisher
StartPage	242
SubjectTerms	Adult Allergic diseases Allergy and Immunology Biological and medical sciences Cells, Cultured Claudin-1 Dermatitis, Atopic - complications Dermatitis, Atopic - genetics Dermatitis, Atopic - microbiology Female Fundamental and applied biological sciences. Psychology Fundamental immunology Genetic Predisposition to Disease Haplotypes Humans Immunopathology Infections Kaposi Varicelliform Eruption - genetics Keratinocytes - metabolism Male Medical sciences Membrane Proteins - genetics Mutation Permeability Polymorphism, Single Nucleotide Proteins Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Skin allergic diseases. Stinging insect allergies Tight Junctions - metabolism Young Adult
Title	Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis
URI	https://www.clinicalkey.com/#!/content/1-s2.0-S0091674911002764 https://www.clinicalkey.es/playcontent/1-s2.0-S0091674911002764 https://dx.doi.org/10.1016/j.jaci.2011.02.014 https://www.ncbi.nlm.nih.gov/pubmed/21489616 https://www.proquest.com/docview/1547844097 https://www.proquest.com/docview/874899670 https://www.proquest.com/docview/883048291
Volume	128
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9wwEBYhhVIope-4TRcdeitOLEurxzGEhm1LcmogN2HLNnVIvSZal-SS394ZS94ltNlCr_bM2p4Zz4zW33wi5KN2QpmmgZUqV00qqpKlpVZVyk1jskKVjo2b9p2eycW5-Hoxv9ghx9MsDMIqY-4POX3M1vHIYbTmYd-2OONrEEJvkPQsVxI5QYVQGOUHdxuYh-E6tMCGpSgdB2cCxuuycG2k8cwPMiYeKk5P-8KDyZqw18XDzehYlE6ek2exm6RH4YZfkJ26e0ken8bv5a8IrC6rQA_radtRd1UMUKtSRn8Wt7TufqDLqR_8iG0ZYbK3dLWk4Me-9tS3SB18Q3-114OnjE7ArfBjsFrvW0erOjS9rX9Nzk8-fz9epHF_hdRBVV6l2ggB7YBsshqsaApXVqxgsiwd50aAF8GyTksjwZfQRzhIqhzJvJ1xao5Cb8hut-zqPZz8BlUNzYKWWhjXmHkloCY6J0ujeMUSwibDWhfJx3EPjCs7ocwuLTrDojNslltwRkI-rXX6QL2xVZpP_rLTUCmkQQuVYauW-ptW7eOb7C2zHiTtH9GWkPla817A_vOKs3vBtH60XHABzalJyP4UXXZzF0i7JpCbLCF0fRoyAX7eKbp6OXirkUjISJVtEdEcMnZuwB9vQ9xuLg_rYiOZfPefz_WePAl_tyOSeZ_srq6H-gP0a6tyNr6QM_Lo6Mu3xdlvHVA9cw
linkProvider	Elsevier
linkToHtml	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9QwEB2VrQRICPFNoBQfuKHQOHYc-1hVVFva3VMr9WYlTiJSlWxU7yL67xnHzq4q6CJxTTxJPDOZeU5mngE-ScNz1TS4UmV5E_OqpHEp8ypmqlFJkZeGDpv2zeZiesG_XWaXO3A09sK4ssoQ-31MH6J1OHIQtHnQt63r8VWuhF450rM0F_wB7Dp2qmwCu4cnp9P5hnuXSY-CFY2dQOid8WVeV4VpA5Nn-iWh_L789KQvLGqt8dtd3I9Hh7x0_AyeBkBJDv0zP4edunsBD2fhl_lLwAVm5RliLWk7Yq6LFaarmJIfxS2pu-_O6sSu7FDeMlTK3pLlgqAp-9oS2zr24F_kZ3uzsoSSsXbLXwwX7H1rSFV73NvaV3Bx_PX8aBqHLRZig4l5GUvFOSIC0SQ1KlIVpqxoQUVZGsYUR0Oico0USqA5EUoYjKvM8XkbZfLMDXoNk27R1W9d8zeKSsQLUkiuTKOyimNaNEaUKmcVjYCOitUm8I-7bTCu9VhodqWdMbQzhk5SjcaI4PNapvfsG1tHs9FeeuwrxUioMTlslcr_JlXb8DJbTbXFkfoPh4sgW0ve8dl_3nH_jjOtp5ZyxhGfqgj2Ru_Sm6dwzGvc0ZNFQNanMRi4PzxFVy9WVkvHJaREnmwZIhkG7VShPd54v93cHpfGSlDx7j_n9REeTc9nZ_rsZH76Hh77r--usHkPJsubVf0B4duy3A-v52_hMUAk
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Reductions+in+claudin-1+may+enhance+susceptibility+to+herpes+simplex+virus+1+infections+in+atopic+dermatitis&rft.jtitle=Journal+of+allergy+and+clinical+immunology&rft.au=De+Benedetto%2C+Anna&rft.au=Slifka%2C+Mark+K.&rft.au=Rafaels%2C+Nicholas+M.&rft.au=Kuo%2C+I-Hsin&rft.date=2011-07-01&rft.pub=Mosby%2C+Inc&rft.issn=0091-6749&rft.volume=128&rft.issue=1&rft.spage=242&rft.epage=246.e5&rft_id=info:doi/10.1016%2Fj.jaci.2011.02.014&rft.externalDocID=S0091674911002764
thumbnail_m	http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F00916749%2FS0091674911X00088%2Fcov150h.gif