Molecular constraints on synaptic tagging and maintenance of long-term potentiation: a predictive model
Protein synthesis-dependent, late long-term potentiation (LTP) and depression (LTD) at glutamatergic hippocampal synapses are well characterized examples of long-term synaptic plasticity. Persistent increased activity of protein kinase M ζ (PKMζ) is thought essential for maintaining LTP. Additional...
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Published in | PLoS computational biology Vol. 8; no. 8; p. e1002620 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
Public Library of Science
01.08.2012
Public Library of Science (PLoS) |
Subjects | |
Online Access | Get full text |
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