Selection-driven cost-efficiency optimization of transcripts modulates gene evolutionary rate in bacteria - Seward, Emily A.; Kelly, Steven (Genome Biology, 2018)
Keywords: Amino acids; Bacteria; Bacteria - genetics; Bacteria - metabolism; Bias; Bioinformatics; biosynthesis; Codon; Codon bias; codon usage; Codons; Copy number; cost effectiveness; Deoxyribonucleic acid; DNA; E coli; Efficiency; Evolution; Evolution, Molecular; Evolutionary genetics; Gene Dosage; Gene evolution; Gene Expression Regulation, Bacterial; Genes; Genetic Code; Genome, Bacterial; Genomes; Genomics; messenger RNA; Mutation; Natural selection; Protein Biosynthesis; Proteins; Resource allocation; RNA, Messenger - genetics; RNA, Messenger - metabolism; RNA, Transfer - genetics; RNA, Transfer - metabolism; Selection, Genetic; Synonymous codon use; Transcription; transfer RNA; Translation; translation (genetics); Translational efficiency; Molecular evolution; Transcript optimization; Gene evolution; Translational efficiency; Synonymous codon use; Codon bias; Bacteria; Natural selection