Impact of extrinsic incubation temperature on natural selection during Zika virus infection of Aedes aegypti and Aedes albopictus

• Published in: PLoS pathogens Vol. 17; no. 11; p. e1009433
• Main Authors: Murrieta, Reyes A., Garcia-Luna, Selene M., Murrieta, Deedra J., Halladay, Gareth, Young, Michael C., Fauver, Joseph R., Gendernalik, Alex, Weger-Lucarelli, James, Rückert, Claudia, Ebel, Gregory D.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.11.2021; Public Library of Science (PLoS)
• Subjects: Aedes; Aedes - classification; Aedes - genetics; Aedes - virology; Aedes aegypti; Aedes albopictus; Ambient temperature; Analysis; Animals; Aquatic insects; Arthropods; Biological effects; Biology and Life Sciences; Chlorocebus aethiops; Culicidae; Environmental aspects; Generalized linear models; Genetic diversity; Genetic Fitness; Genetic vectors; Identification and classification; Infections; Medicine and Health Sciences; Mosquito Vectors - virology; Mosquitoes; Natural selection; Observations; Population; Population dynamics; Population structure; Positive selection; Prevention; Saliva - virology; Selection, Genetic; Temperature; Temperature effects; Tropical environments; Vector-borne diseases; Vero Cells; Vertebrates; Viral Load; Viruses; West Nile virus; Zika virus; Zika Virus - growth & development; Zika Virus Infection - transmission; Zika Virus Infection - virology; United States

Arthropod-borne viruses (arboviruses) require replication across a wide range of temperatures to perpetuate. While vertebrate hosts tend to maintain temperatures of approximately 37°C—40°C, arthropods are subject to ambient temperatures which can have a daily fluctuation of > 10°C. Temperatures i...