Influenza-A mediated pre-existing immunity levels to SARS-CoV-2 could predict early COVID-19 outbreak dynamics

• Published in: iScience Vol. 26; no. 12; p. 108441
• Main Authors: Almazán, Nerea Martín, Rahbar, Afsar, Carlsson, Marcus, Hoffman, Tove, Kolstad, Linda, Rönnberg, Bengt, Pantalone, Mattia Russel, Fuchs, Ilona Lewensohn, Nauclér, Anna, Ohlin, Mats, Sacharczuk, Mariusz, Religa, Piotr, Amér, Stefan, Molnár, Christian, Lundkvist, Åke, Susrud, Andres, Sörensen, Birger, Söderberg-Nauclér, Cecilia
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.12.2023; Elsevier
• Subjects: Basic Medicine; Immune response; Immunologi inom det medicinska området; Immunology; Immunology in the medical area; Medical and Health Sciences; Medicin och hälsovetenskap; Medicinska och farmaceutiska grundvetenskaper; Virology; Immunology; Immune response; Virology

Susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is highly variable and could be mediated by a cross-protective pre-immunity. We identified 14 cross-reactive peptides between SARS-CoV-2 and influenza A H1N1, H3N2, and human herpesvirus (HHV)-6A/B with potenti...