Demographic and Clinical Predictors of Mortality from Highly Pathogenic Avian Influenza A (H5N1) Virus Infection: CART Analysis of International Cases

• Published in: PloS one Vol. 9; no. 3; p. e91630
• Main Authors: Patel, Rita B., Mathur, Maya B., Gould, Michael, Uyeki, Timothy M., Bhattacharya, Jay, Xiao, Yang, Khazeni, Nayer
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 25.03.2014; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Avian flu; Avian influenza; Avian influenza viruses; Biology and life sciences; Bivariate analysis; Child; Child, Preschool; Demographics; Demography; Epidemics; Female; Follow-Up Studies; Health care costs; Health Expenditures; Hospitalization; Humans; Identification methods; Infant; Infant, Newborn; Infection; Infections; Influenza; Influenza A; Influenza A Virus, H5N1 Subtype - pathogenicity; Influenza, Human - mortality; Influenza, Human - virology; International Agencies; Male; Medicine and Health Sciences; Models, Statistical; Morbidity; Mortality; Patient outcomes; Prognosis; Public health; Regression analysis; Research and Analysis Methods; Risk analysis; Risk Factors; ROC Curve; Scientific papers; Search engines; Social Sciences; Statistical analysis; Survival Rate; Systematic review; Therapeutic applications; Viruses; Young Adult; Southeast Asia; California; United States > US; China

Human infections with highly pathogenic avian influenza (HPAI) A (H5N1) viruses have occurred in 15 countries, with high mortality to date. Determining risk factors for morbidity and mortality from HPAI H5N1 can inform preventive and therapeutic interventions. We included all cases of human HPAI H5N...