Bacterial metabolites of diet-derived lignans and isoflavones inversely associate with asthma and wheezing

• Published in: Journal of allergy and clinical immunology Vol. 135; no. 1; pp. 267 - 269.e14
• Main Authors: Cardet, Juan-Carlos, Johns, Christina B., Savage, Jessica H.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2015; Elsevier Limited
• Subjects: Adolescent; Adult; Age; Aged; Aged, 80 and over; Allergy and Immunology; Asthma - urine; Bacteria - metabolism; Body mass index; Child; Diet; Dietary fiber; Ethnicity; Family medical history; Female; Flax; Humans; Isoflavones - metabolism; Isoflavones - urine; Lignans - metabolism; Lignans - urine; Male; Metabolism; Metabolites; Middle Aged; Nutrition Surveys; Respiratory Sounds; Studies; Young Adult

A total of 9633 subjects aged 6 to 85 years had complete data for the primary analyses of the association between urinary levels of lignan and isoflavone metabolites (eg, enterolactone, equol, and O-DMA) and physician-diagnosed current asthma and self-reported nonasthmatic wheeze, adjusting for age,...