Asymmetric photoredox transition-metal catalysis activated by visible light

• Published in: Nature (London) Vol. 515; no. 7525; pp. 100 - 103
• Main Authors: Huo, Haohua, Shen, Xiaodong, Wang, Chuanyong, Zhang, Lilu, Röse, Philipp, Chen, Liang-An, Harms, Klaus, Marsch, Michael, Hilt, Gerhard, Meggers, Eric
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 06.11.2014; Nature Publishing Group
• Subjects: 639/638/403; 639/638/77/890; Anions; Atmospheric chemistry; Catalysis; Cations; Chemical properties; Chemical research; Crystal structure; Humanities and Social Sciences; Iridium; letter; Ligands; Light; multidisciplinary; Oxidation-reduction reaction; Photochemicals; Science; Transition metals

A chiral iridium complex serves as a sensitizer for photoredox catalysis and at the same time provides very effective asymmetric induction for the enantioselective alkylation of 2-acyl imidazoles; the metal centre simultaneously serves as the exclusive source of chirality, the catalytically active L...