Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche - Roulis, Manolis; Kaklamanos, Aimilios; Schernthanner, Marina; Bielecki, Piotr; Zhao, Jun; Kaffe, Eleanna; Frommelt, Laura-Sophie; Qu, Rihao; Knapp, Marlene S.; Henriques, Ana; Chalkidi, Niki; Koliaraki, Vasiliki; et al. (Nature (London), 2020)
Keywords: 13/1; 13/100; 13/106; 13/31; 13/51; 14; 14/19; 14/28; 14/63; 14/69; 38; 38/62; 38/90; 38/91; 59; 631/532/2139; 631/532/2437; 631/67/1504/1885; 631/67/327; 631/80/304; 64; 64/110; 64/60; 82; 82/16; 82/51; 82/58; 96; Ablation; Adaptor Proteins, Signal Transducing - metabolism; Analysis; Animals; Antigens, Ly - metabolism; Arachidonic acid; Arachidonic Acid - metabolism; Carcinogenesis; Cell Cycle Proteins - metabolism; Cell Proliferation; Cellular signal transduction; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - metabolism; Colorectal Neoplasms - pathology; Cyclooxygenase 2 - metabolism; Dephosphorylation; Development and progression; Dinoprostone - metabolism; Female; Fibroblasts; Fibroblasts - metabolism; Fibroblasts - pathology; Gastrointestinal cancer; Gene sequencing; Genetic aspects; Heterogeneity; Humanities and Social Sciences; Humans; Intestinal Mucosa - metabolism; Intestinal Mucosa - pathology; Intestine; Intestines - pathology; Localization; Male; Membrane Proteins - metabolism; Mesenchyme; Mesoderm - metabolism; Mesoderm - pathology; Mice; multidisciplinary; Mutants; Mutation; Neoplastic Stem Cells - metabolism; Neoplastic Stem Cells - pathology; Nuclear transport; Organoids; Organoids - metabolism; Organoids - pathology; Paracrine Communication; Paracrine signalling; Population; Prostaglandin E2; Receptors, Prostaglandin E, EP4 Subtype - metabolism; Ribonucleic acid; RNA; Robust control; Science; Science (multidisciplinary); Sequence analysis; Signal transduction; Signaling; Single-Cell Analysis; Small intestine; Stem Cell Niche; Stem cell transplantation; Stem cells; Transcription; Translocation; Tumorigenesis; Tumors; YAP-Signaling Proteins