Dopamine D1 receptor modulation in nucleus accumbens lowers voluntary wheel running in rats bred to run high distances - Roberts, Michael D.; Gilpin, Leigh; Parker, Kyle E.; Childs, Thomas E.; Will, Matthew J.; Booth, Frank W. (Physiology & behavior, 2012)
Keywords: Addiction; agonists; Analysis of Variance; Animal subjects; Animals; antagonists; Behavior; Behavioral psychophysiology; Biological and medical sciences; Body Mass Index; Brain-derived neurotrophic factor; Data processing; Dopamine; Dopamine Agents - pharmacology; Dopamine D1 receptors; Dopamine D2 receptors; Dopamine D5 receptors; dopamine receptors; Drug abuse; Drug development; Drugs; Eating - drug effects; Exercise; Exercise physiology; Female; FosB protein; Fundamental and applied biological sciences. Psychology; Gene expression; Gene Expression Regulation - drug effects; Gene Expression Regulation - genetics; genes; illicit drugs; Injections; messenger RNA; Motivation; Motor Activity - drug effects; Motor Activity - genetics; Motor Activity - physiology; Nerve Tissue Proteins - genetics; Nerve Tissue Proteins - metabolism; Nucleus accumbens; Nucleus Accumbens - drug effects; Nucleus Accumbens - physiology; Obesity; phenotype; Physical training; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Rats; Rats, Wistar; Receptors, Dopamine D1 - genetics; Receptors, Dopamine D1 - metabolism; Receptors, Dopamine D1 - physiology; Reinforcement; Reward; RNA, Messenger - genetics; RNA, Messenger - metabolism; Running; Running - physiology; Selective breeding; Signal transduction; Time Factors; Wheel running; Nucleus accumbens; Exercise; Dopamine; Motivation; Selective breeding; Physical exercise; Rat; Rodentia; Central nervous system; D1 Dopamine receptor; Basal ganglion; Catecholamine; Encephalon; Vertebrata; Mammalia; Running-wheel; Animal; Neurotransmitter