The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature - Qin, Zhenyu (Atherosclerosis, 2012)
Keywords: adipocytes; Adipocytes - pathology; adipose tissue; atherogenesis; atherosclerosis; Atherosclerosis (general aspects, experimental research); Biological and medical sciences; Blood and lymphatic vessels; Blood Platelets; Blood Platelets - pathology; Blood Vessels; Blood Vessels - metabolism; Blood Vessels - pathology; Blood vessels and receptors; Cardiology. Vascular system; Cardiovascular; Cell Communication; Cell Line, Tumor; diabetes mellitus; endothelial cells; Endothelial Cells - pathology; Epigenesis, Genetic; Epigenetics; Fundamental and applied biological sciences. Psychology; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; genetics; glucose; histones; Humans; inflammation; leukemia; Leukemia, Monocytic, Acute; Leukemia, Monocytic, Acute - genetics; Leukemia, Monocytic, Acute - metabolism; Leukemia, Monocytic, Acute - pathology; lipopolysaccharides; low density lipoprotein; Macrophage; macrophages; Macrophages - metabolism; Macrophages - pathology; Medical sciences; metabolism; microRNA; MicroRNAs; MicroRNAs - metabolism; Monocyte; monocytes; Monocytes - metabolism; Monocytes - pathology; myocytes; Myocytes, Smooth Muscle; Myocytes, Smooth Muscle - pathology; obesity; pathology; pathophysiology; patients; physiology; smooth muscle; T-lymphocytes; T-Lymphocytes - pathology; Transcriptome; Vascular Diseases; Vascular Diseases - genetics; Vascular Diseases - metabolism; Vascular Diseases - pathology; Vertebrates: cardiovascular system; CE; TPA; Monocyte; PMA; Transcriptome; CM; siRNA; 1α,25(OH)2D3; PBMC; LPS; pTHP-1 cells; TG; LDL; HAEC; PDGF; Epigenetics; HUVEC; miRNA; microRNA; VSMC; Macrophage; triglyceride; low density lipoprotein; 1α, 25-dihydroxyvitamin D 3; 1α,25(OH) 2D 3; chylomicron; platelet-derived growth factor; PMA treated THP-1 cells; human aortic endothelial cell; small interfering RNA; phorbol-12-myristate-13-acetate; 12-O-tetradecanoylphorbol-13-acetate