The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature

Since their establishment thirty years ago, THP-1 cells have become one of most widely used cell lines to investigate the function and regulation of monocytes and macrophages in the cardiovascular system. However, because this cell line was derived from the blood of a patient with acute monocytic le...

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Published in	Atherosclerosis Vol. 221; no. 1; pp. 2 - 11
Main Author	Qin, Zhenyu
Format	Journal Article
Language	English
Published	Amsterdam Elsevier Ireland Ltd 01.03.2012 Elsevier
Subjects	adipocytes Adipocytes - pathology adipose tissue atherogenesis atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood Platelets Blood Platelets - pathology Blood Vessels Blood Vessels - metabolism Blood Vessels - pathology Blood vessels and receptors Cardiology. Vascular system Cardiovascular Cell Communication Cell Line, Tumor diabetes mellitus endothelial cells Endothelial Cells - pathology Epigenesis, Genetic Epigenetics Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Regulation, Neoplastic genetics glucose histones Humans inflammation leukemia Leukemia, Monocytic, Acute Leukemia, Monocytic, Acute - genetics Leukemia, Monocytic, Acute - metabolism Leukemia, Monocytic, Acute - pathology lipopolysaccharides low density lipoprotein Macrophage macrophages Macrophages - metabolism Macrophages - pathology Medical sciences metabolism microRNA MicroRNAs MicroRNAs - metabolism Monocyte monocytes Monocytes - metabolism Monocytes - pathology myocytes Myocytes, Smooth Muscle Myocytes, Smooth Muscle - pathology obesity pathology pathophysiology patients physiology smooth muscle T-lymphocytes T-Lymphocytes - pathology Transcriptome Vascular Diseases Vascular Diseases - genetics Vascular Diseases - metabolism Vascular Diseases - pathology Vertebrates: cardiovascular system CE TPA Monocyte PMA Transcriptome CM siRNA 1α,25(OH)2D3 PBMC LPS pTHP-1 cells TG LDL HAEC PDGF Epigenetics HUVEC miRNA microRNA VSMC Macrophage triglyceride low density lipoprotein 1α, 25-dihydroxyvitamin D 3 1α,25(OH) 2D 3 chylomicron platelet-derived growth factor PMA treated THP-1 cells human aortic endothelial cell small interfering RNA phorbol-12-myristate-13-acetate 12-O-tetradecanoylphorbol-13-acetate human umbilical vein endothelial cell vascular smooth muscle cell lipopolysaccharide cholesteryl ester peripheral blood mononuclear cell Vascular disease Atherosclerosis Cardiovascular disease Differential diagnostic
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Abstract	Since their establishment thirty years ago, THP-1 cells have become one of most widely used cell lines to investigate the function and regulation of monocytes and macrophages in the cardiovascular system. However, because this cell line was derived from the blood of a patient with acute monocytic leukemia, the extent to which THP-1 cells mimic monocytes and macrophages in the vasculature is not entirely known. This article serves as a meaningful attempt to address this question by reviewing the recent publications. The interactions between THP-1 cells and various vascular cells (such as endothelial cells, smooth muscle cells, adipocytes, and T cells) provide insight into the roles of the interconnection of monocytes–macrophages with other vascular cells during vascular inflammation, particularly atherogenesis and obesity. Transcriptome, microRNA profile, and histone modifications of THP-1 cells shed new light on the regulatory mechanism of the monocytes–macrophages in response to various inflammatory mediators, such as oxidized low density lipoprotein, lipopolysaccharide, and glucose. These studies hint that under certain defined conditions, THP-1 cells not only resemble primary monocytes–macrophages isolated from healthy donors or donors with disease, such as diabetes mellitus, but also mimic the in situ alteration of macrophages in the adipose tissue of obese subjects and in atherosclerotic lesions. A potential trajectory is to use this cell line to study the novel molecular mechanisms in monocytes and macrophages in relation to the physiology and pathophysiology of the cardiovascular system, however, the conclusion of studies employing THP-1 cells requires further verification using primary cells and/or in vivo models to be generalized to monocytes and macrophages.
AbstractList	Since their establishment thirty years ago, THP-1 cells have become one of most widely used cell lines to investigate the function and regulation of monocytes and macrophages in the cardiovascular system. However, because this cell line was derived from the blood of a patient with acute monocytic leukemia, the extent to which THP-1 cells mimic monocytes and macrophages in the vasculature is not entirely known. This article serves as a meaningful attempt to address this question by reviewing the recent publications. The interactions between THP-1 cells and various vascular cells (such as endothelial cells, smooth muscle cells, adipocytes, and T cells) provide insight into the roles of the interconnection of monocytes–macrophages with other vascular cells during vascular inflammation, particularly atherogenesis and obesity. Transcriptome, microRNA profile, and histone modifications of THP-1 cells shed new light on the regulatory mechanism of the monocytes–macrophages in response to various inflammatory mediators, such as oxidized low density lipoprotein, lipopolysaccharide, and glucose. These studies hint that under certain defined conditions, THP-1 cells not only resemble primary monocytes–macrophages isolated from healthy donors or donors with disease, such as diabetes mellitus, but also mimic the in situ alteration of macrophages in the adipose tissue of obese subjects and in atherosclerotic lesions. A potential trajectory is to use this cell line to study the novel molecular mechanisms in monocytes and macrophages in relation to the physiology and pathophysiology of the cardiovascular system, however, the conclusion of studies employing THP-1 cells requires further verification using primary cells and/or in vivo models to be generalized to monocytes and macrophages. Since their establishment thirty years ago, THP-1 cells have become one of most widely used cell lines to investigate the function and regulation of monocytes and macrophages in the cardiovascular system. However, because this cell line was derived from the blood of a patient with acute monocytic leukemia, the extent to which THP-1 cells mimic monocytes and macrophages in the vasculature is not entirely known. This article serves as a meaningful attempt to address this question by reviewing the recent publications. The interactions between THP-1 cells and various vascular cells (such as endothelial cells, smooth muscle cells, adipocytes, and T cells) provide insight into the roles of the interconnection of monocytes-macrophages with other vascular cells during vascular inflammation, particularly atherogenesis and obesity. Transcriptome, microRNA profile, and histone modifications of THP-1 cells shed new light on the regulatory mechanism of the monocytes-macrophages in response to various inflammatory mediators, such as oxidized low density lipoprotein, lipopolysaccharide, and glucose. These studies hint that under certain defined conditions, THP-1 cells not only resemble primary monocytes-macrophages isolated from healthy donors or donors with disease, such as diabetes mellitus, but also mimic the in situ alteration of macrophages in the adipose tissue of obese subjects and in atherosclerotic lesions. A potential trajectory is to use this cell line to study the novel molecular mechanisms in monocytes and macrophages in relation to the physiology and pathophysiology of the cardiovascular system, however, the conclusion of studies employing THP-1 cells requires further verification using primary cells and/or in vivo models to be generalized to monocytes and macrophages.Since their establishment thirty years ago, THP-1 cells have become one of most widely used cell lines to investigate the function and regulation of monocytes and macrophages in the cardiovascular system. However, because this cell line was derived from the blood of a patient with acute monocytic leukemia, the extent to which THP-1 cells mimic monocytes and macrophages in the vasculature is not entirely known. This article serves as a meaningful attempt to address this question by reviewing the recent publications. The interactions between THP-1 cells and various vascular cells (such as endothelial cells, smooth muscle cells, adipocytes, and T cells) provide insight into the roles of the interconnection of monocytes-macrophages with other vascular cells during vascular inflammation, particularly atherogenesis and obesity. Transcriptome, microRNA profile, and histone modifications of THP-1 cells shed new light on the regulatory mechanism of the monocytes-macrophages in response to various inflammatory mediators, such as oxidized low density lipoprotein, lipopolysaccharide, and glucose. These studies hint that under certain defined conditions, THP-1 cells not only resemble primary monocytes-macrophages isolated from healthy donors or donors with disease, such as diabetes mellitus, but also mimic the in situ alteration of macrophages in the adipose tissue of obese subjects and in atherosclerotic lesions. A potential trajectory is to use this cell line to study the novel molecular mechanisms in monocytes and macrophages in relation to the physiology and pathophysiology of the cardiovascular system, however, the conclusion of studies employing THP-1 cells requires further verification using primary cells and/or in vivo models to be generalized to monocytes and macrophages. Abstract Since their establishment thirty years ago, THP-1 cells have become one of most widely used cell lines to investigate the function and regulation of monocytes and macrophages in the cardiovascular system. However, because this cell line was derived from the blood of a patient with acute monocytic leukemia, the extent to which THP-1 cells mimic monocytes and macrophages in the vasculature is not entirely known. This article serves as a meaningful attempt to address this question by reviewing the recent publications. The interactions between THP-1 cells and various vascular cells (such as endothelial cells, smooth muscle cells, adipocytes, and T cells) provide insight into the roles of the interconnection of monocytes–macrophages with other vascular cells during vascular inflammation, particularly atherogenesis and obesity. Transcriptome, microRNA profile, and histone modifications of THP-1 cells shed new light on the regulatory mechanism of the monocytes–macrophages in response to various inflammatory mediators, such as oxidized low density lipoprotein, lipopolysaccharide, and glucose. These studies hint that under certain defined conditions, THP-1 cells not only resemble primary monocytes–macrophages isolated from healthy donors or donors with disease, such as diabetes mellitus, but also mimic the in situ alteration of macrophages in the adipose tissue of obese subjects and in atherosclerotic lesions. A potential trajectory is to use this cell line to study the novel molecular mechanisms in monocytes and macrophages in relation to the physiology and pathophysiology of the cardiovascular system, however, the conclusion of studies employing THP-1 cells requires further verification using primary cells and/or in vivo models to be generalized to monocytes and macrophages.
Author	Qin, Zhenyu
Author_xml	– sequence: 1 givenname: Zhenyu surname: Qin fullname: Qin, Zhenyu email: qinz@uthscsa.edu organization: Division of Vascular Surgery, Department of Surgery, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, United States
BackLink	http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25698861$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/21978918$$D View this record in MEDLINE/PubMed
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Cites_doi	10.1128/IAI.00277-07 10.1152/physiolgenomics.00296.2005 10.5551/jat.11.88 10.1182/blood.V88.1.146.146 10.1086/432487 10.1194/jlr.R800059-JLR200 10.1038/nature02871 10.1073/pnas.0610731104 10.1161/CIRCRESAHA.107.151746 10.1194/jlr.M400195-JLR200 10.1124/jpet.105.095976 10.4049/jimmunol.147.10.3408 10.1161/01.RES.0000176530.66400.48 10.1172/JCI117501 10.1161/01.CIR.103.8.1057 10.1002/ijc.2910260208 10.1016/S0022-2275(20)37569-6 10.1161/01.RES.0000207394.39249.fc 10.1096/fj.11-181149 10.1016/j.regpep.2009.05.002 10.1182/blood.V92.4.1259 10.1038/nature02625 10.1093/nar/gkl386 10.1002/jlb.39.4.409 10.1161/CIRCULATIONAHA.106.622514 10.1194/jlr.M400324-JLR200 10.1007/s00125-006-0253-0 10.1084/jem.20012044 10.1128/IAI.00326-06 10.1038/362801a0 10.1172/JCI7811 10.1161/CIRCRESAHA.107.164988 10.1016/S0021-9150(96)06042-X 10.1038/nrg1379 10.1038/ng1531 10.1016/j.it.2004.09.015 10.1074/jbc.M109.035683 10.1073/pnas.0732111100 10.1016/0022-1759(94)90158-9 10.1016/j.metabol.2007.11.005 10.1074/jbc.M601103200 10.1074/jbc.M200705200 10.1161/01.ATV.18.10.1589 10.1152/ajpcell.00170.2004 10.1016/j.bbrc.2007.09.074 10.1097/MED.0b013e32833727a1 10.1016/j.regpep.2008.05.002 10.1016/j.bbrc.2004.04.021 10.1074/jbc.M500543200 10.1016/S0021-9150(99)00397-4 10.1074/jbc.M605633200 10.1101/pdb.prot5612 10.1074/jbc.M106114200 10.1084/jem.20072108 10.1016/j.jim.2009.03.014 10.1016/j.freeradbiomed.2004.04.016 10.1038/sj.ijo.0801520 10.3317/jraas.2007.007 10.1016/j.imlet.2007.07.003 10.1046/j.1365-2567.2001.01274.x 10.1172/JCI119754 10.1161/01.RES.0000026421.61398.F2 10.1074/jbc.M403618200 10.1161/01.RES.0000038341.34243.64 10.4049/jimmunol.1000660 10.1097/00005344-200008000-00003 10.1074/jbc.M401178200 10.1093/oxfordjournals.jbchem.a122882 10.1074/jbc.M806322200 10.1074/jbc.M409101200 10.1186/1471-2172-8-1 10.1161/01.RES.83.3.270 10.1194/jlr.M600304-JLR200 10.1016/S0021-9258(17)43931-7 10.1074/jbc.M110.112599 10.1124/mol.104.006445 10.1152/ajpendo.00329.2010 10.1073/pnas.032665099 10.1074/jbc.275.15.11181 10.1074/jbc.M603417200 10.1128/AAC.01095-06 10.4049/jimmunol.141.8.2656 10.1016/S0008-6363(98)00302-2 10.1074/jbc.M302309200 10.1016/j.mce.2011.04.004 10.1182/blood.V93.12.4059 10.1189/jlb.72.3.417 10.1074/jbc.M609446200 10.1038/nrg1328 10.1128/IAI.71.4.2087-2094.2003 10.1161/CIRCRESAHA.110.222083 10.1016/j.diabres.2010.08.019 10.1371/journal.pone.0008668 10.1111/j.1749-6632.2003.tb07447.x 10.1161/hc0502.102969 10.1073/pnas.0605298103 10.1161/01.CIR.0000158484.18024.1F 10.1038/nrcardio.2010.104 10.1038/ijo.2008.7 10.1038/79189 10.1016/S0021-9258(18)68596-5 10.1074/jbc.M406741200 10.1016/j.bbalip.2006.05.014 10.1161/CIRCRESAHA.107.156554 10.1111/j.1537-2995.2007.01441.x 10.4049/jimmunol.150.12.5330 10.1161/CIRCULATIONAHA.110.956839 10.1194/jlr.M500207-JLR200 10.1002/jlb.59.4.555 10.1074/jbc.271.15.8837 10.1172/JCI108450 10.1111/j.1462-5822.2004.00388.x 10.1016/0021-9150(95)05695-5 10.1007/BF02041244 10.1016/S0022-2275(20)31492-9 10.1016/S0022-2275(20)42241-2 10.1074/jbc.M004732200 10.4049/jimmunol.146.5.1541 10.1016/S0002-9440(10)63819-9 10.1191/1358863x02vm418oa 10.4049/jimmunol.1001633
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References	Altieri, Edgington (bib0115) 1988; 263 Li, Isler, Dayer, Burger (bib0280) 1995; 84 Bartel, Chen (bib0435) 2004; 5 Fraga, Ballestar, Villar-Garea, Boix-Chornet, Espada, Schotta (bib0515) 2005; 37 Szanto, Nagy (bib0355) 2005; 67 Kohro, Tanaka, Murakami, Wada, Aburatani, Hamakubo (bib0425) 2004; 11 Schwende, Fitzke, Ambs, Dieter (bib0015) 1996; 59 Daigneault, Preston, Marriott, Whyte, Dockrell (bib0020) 2010; 5 Ordovas, Smith (bib0505) 2010; 7 Zhao, Howatt, Gizard, Nomiyama, Findeisen, Heywood (bib0185) 2010; 107 Ross (bib0490) 1993; 362 Adib-Conquy, Cavaillon (bib0555) 2002; 277 Sonna, Kuhlmeier, Carter, Hasday, Lilly, Fairchild (bib0365) 2006; 26 Mahmood Hussain (bib0190) 2000; 148 Diacovo, Roth, Buccola, Bainton, Springer (bib0305) 1996; 88 Lee, Kang, Chong (bib0055) 2005; 280 Ragno, Romano, Howell, Pappin, Jenner, Colston (bib0400) 2001; 104 Halvorsen, Waehre, Scholz, Clausen, von der Thusen, Muller (bib0610) 2005; 46 Banka, Black, Dyer, Curtiss (bib0140) 1991; 32 Kunnari, Savolainen, Ukkola, Kesäniemi, Jokela (bib0595) 2009; 157 Ambros (bib0430) 2004; 431 O’Connell, Taganov, Boldin, Cheng, Baltimore (bib0460) 2007; 104 Sharif, Bolshakov, Raines, Newham, Perkins (bib0420) 2007; 8 Cousins, Blanchard, Popp, Liu, Cao, Moore (bib0035) 2003; 100 Guzzo, Che Mat, Gee (bib0625) 2010; 285 Qiu, Ho, Yu, Hill (bib0370) 2007; 48 Maess, Buers, Robenek, Lorkowski (bib0095) 2011; 2011 Mangan, Wahl (bib0550) 1991; 147 Pollard, Currie, Rosenberger, Heale, Finlay, Speert (bib0405) 2004; 6 Mantovani, Sica, Sozzani, Allavena, Vecchi, Locati (bib0105) 2004; 25 Miao, Wu, Zhang, Yuan, Riggs, Natarajan (bib0520) 2007; 282 Wang, Zhang, Theel, Barb, Munson, Danner (bib0340) 2006; 34 Li, Mouillesseaux, Montoya, Cruz, Gharavi, Dun (bib0155) 2006; 98 Mangan, Welch, Wahl (bib0545) 1991; 146 Ioshikhes, Zhang (bib0525) 2000; 26 Schnoor, Buers, Sietmann, Brodde, Hofnagel, Robenek (bib0090) 2009; 344 Menju, Tajima, Yamamoto (bib0135) 1989; 106 Qin (bib0220) 2008; 150 Fabunmi, Sukhova, Sugiyama, Libby (bib0615) 1998; 83 Han, Ryu, Hong, Ko, Pak, Kim (bib0080) 2005; 111 Spencer, Yao-Borengasser, Unal, Rasouli, Gurley, Zhu (bib0110) 2010; 299 Rutherford, Martin, Salame, Carrier, Anggard, Ferns (bib0225) 1997; 130 Glick, Adelman, Phillips, Rothblat (bib0570) 1983; 258 McDaniel, Thornton, McDaniel (bib0415) 2004; 119 Mancl, Hu, Sangster-Guity, Olshalsky, Hoops, Fitzgerald-Bocarsly (bib0600) 2005; 280 Motiwala, Janagama, Paustian, Zhu, Bannantine, Kapur (bib0395) 2006; 74 Barker, Liu, Rogers (bib0380) 2005; 192 Katz, Shipley, Small (bib0565) 1976; 58 Tsuchiya, Yamabe, Yamaguchi, Kobayashi, Konno, Tada (bib0005) 1980; 26 Chait, Bornfeldt (bib0510) 2009; 50 Singal, Ginder (bib0530) 1999; 93 Lada, Willingham, St Clair (bib0560) 2002; 43 Goldberg (bib0195) 1996; 37 Tintut, Patel, Territo, Saini, Parhami, Demer (bib0230) 2002; 105 Handy, Castro, Loscalzo (bib0500) 2011; 123 Chen, Ross (bib0350) 2007; 232 Carayol, Chen, Yang, Jin, Jin, States (bib0335) 2006; 281 Reyes Garcia, Rozas Moreno, Munoz-Torres (bib0240) 2010; 92 Dogra, Warburton, McMaster (bib0385) 2007; 75 Furman, Rundlof, Larigauderie, Jaye, Bricca, Copin (bib0075) 2004; 37 Taganov, Boldin, Chang, Baltimore (bib0455) 2006; 103 Aslam, Kim, Speck, Seetanah, Molinski, Freedman (bib0310) 2007; 47 Zeyda, Stulnig (bib0245) 2007; 112 Graham, Angell, Jepson, Yeaman, Hassall (bib0145) 1996; 120 Wang, Tabas, Winchester, Ravalli, Rabbani, Tall (bib0130) 1996; 271 Gonsalves, Kalra (bib0475) 2010; 185 Dowds, Masumoto, Zhu, Inohara, Nunez (bib0045) 2004; 279 Okamoto, Folco, Minami, Wara, Feinberg, Sukhova (bib0065) 2008; 102 Fuentes, Hernandez, Fernandez-Aviles, Crespo, Nieto (bib0285) 2002; 91 Auwerx (bib0025) 1991; 47 Zhu, Hojo, Ikeda, Takahashi, Shimada (bib0215) 2000; 36 Simon, Dhen, Seifert, Edelman, Ballantyne, Rogers (bib0300) 2000; 105 Mikita, Porter, Lawn, Shiffman (bib0325) 2001; 276 Lu, Rentero, Raftery, Borges, Bryant, Tedla (bib0605) 2009; 284 Ouchi, Kihara, Arita, Nishida, Matsuyama, Okamoto (bib0060) 2001; 103 Altieri, Edgington (bib0100) 1988; 141 Cai, Lanting, Natarajan (bib0200) 2004; 287 Tone, Shikata, Ogawa, Sasaki, Nagase, Sasaki (bib0360) 2007; 8 He, Hannon (bib0440) 2004; 5 O’Connell, Rao, Chaudhuri, Boldin, Taganov, Nicoll (bib0465) 2008; 205 Iwamoto, Abe-Dohmae, Ayaori, Tanaka, Kusuhara, Ohsuzu (bib0070) 2007; 101 Constant, Gagnon, Yarmo, Sorisky (bib0255) 2008; 57 Hulsmans, De Keyzer, Holvoet (bib0450) 2011; 25 Cohen, Bouaboula, Bellis, Baron, Jbilo, Poinot-Chazel (bib0390) 2000; 275 McCaffrey, Du, Consigli, Szabo, Bray, Hartner (bib0495) 1997; 100 Kritharides, Christian, Stoudt, Morel, Rothblat (bib0575) 1998; 18 Kawakami, Aikawa, Alcaide, Luscinskas, Libby, Sacks (bib0165) 2006; 114 Kudrin, Scott, Martin, Chung, Donn, McMaster (bib0620) 2006; 281 Sneddon, McLeod, Wahle, Arthur (bib0180) 2006; 1761 Rogers, Thornton, Barker, McDaniel, Sacks, Swiatlo (bib0030) 2003; 71 Vickers, Remaley (bib0445) 2010; 17 Tsuchiya, Kobayashi, Goto, Okumura, Nakae, Konno, Tada (bib0010) 1982; 42 Simitsopoulou, Roilides, Likartsis, Ioannidis, Orfanou, Paliogianni (bib0375) 2007; 51 Li, Hou, Guo, Yang, Liu, Zhang (bib0470) 2011; 186 Zhao, Fisher, St Clair, Rudel, Ghosh (bib0585) 2005; 46 Zhang, Qi, Xian, Yang, Blackstein, Deng (bib0150) 2008; 102 Keuper, Bluher, Schon, Moller, Dzyakanchuk, Amrein (bib0270) 2011; 339 Hiltunen, Turunen, Hakkinen, Rutanen, Hedman, Makinen (bib0535) 2002; 7 Llaverias, Noe, Penuelas, Vazquez-Carrera, Sanchez, Laguna (bib0330) 2004; 318 Krakauer (bib0175) 1994; 177 Gee, Kozlowski, Kumar (bib0590) 2003; 278 Kaplanski, Marin, Fabrigoule, Boulay, Benoliel, Bongrand (bib0170) 1998; 92 Braun, Pietsch, Schror, Baumann, Felix (bib0210) 1999; 41 Fitzpatrick, Severson, Edwards, Ingram (bib0235) 1994; 94 Whatling, Bjork, Gredmark, Hamsten, Eriksson (bib0320) 2004; 45 Burke, Sumner, Maitland, Lewis (bib0040) 2002; 72 Massberg, Brand, Gruner, Page, Muller, Muller (bib0295) 2002; 196 Shiffman, Mikita, Tai, Wade, Porter, Seilhamer (bib0315) 2000; 275 Johnson, Yabu, Hanson, Shah, Zager (bib0630) 2003; 162 Gupta, Dai, Datta, Garber, Grenett, Li (bib0160) 2005; 97 Stout, Suttles (bib0275) 1993; 150 Dadgostar, Zarnegar, Hoffmann, Qin, Truong, Rao (bib0290) 2002; 99 Wabitsch, Brenner, Melzner, Braun, Moller, Heinze (bib0265) 2001; 25 Unoki, Bujo, Jiang, Kawamura, Murakami, Saito (bib0260) 2008; 32 Persson, Degerman, Nilsson, Lindholm (bib0580) 2007; 363 Shanmugam, Reddy, Natarajan (bib0480) 2008; 283 Constant, Gagnon, Landry, Sorisky (bib0250) 2006; 49 Lund, Andersson, Lauria, Lindholm, Fraga, Villar-Garea (bib0540) 2004; 279 Xue, Lai, Huang, Gu, Karlsson, Fourie (bib0345) 2006; 317 Liang, Seyrantepe, Landry, Ahmad, Ahmad, Stamatos (bib0050) 2006; 281 Egger, Liang, Aparicio, Jones (bib0485) 2004; 429 Shioi, Katagi, Okuno, Mori, Jono, Koyama (bib0205) 2002; 91 Gaffney, Dell’Aquila, Lingenfelter, Huffnagle, Wiest (bib0125) 1986; 39 Ren, Robertson, Howe, Barrows, Heinzen (bib0410) 2003; 990 Bruey, Bruey-Sedano, Newman, Chandler, Stehlik, Reed (bib0085) 2004; 279 Bruey (10.1016/j.atherosclerosis.2011.09.003_bib0085) 2004; 279 Tintut (10.1016/j.atherosclerosis.2011.09.003_bib0230) 2002; 105 Daigneault (10.1016/j.atherosclerosis.2011.09.003_bib0020) 2010; 5 Auwerx (10.1016/j.atherosclerosis.2011.09.003_bib0025) 1991; 47 O’Connell (10.1016/j.atherosclerosis.2011.09.003_bib0460) 2007; 104 Shioi (10.1016/j.atherosclerosis.2011.09.003_bib0205) 2002; 91 Dogra (10.1016/j.atherosclerosis.2011.09.003_bib0385) 2007; 75 Chait (10.1016/j.atherosclerosis.2011.09.003_bib0510) 2009; 50 Fitzpatrick (10.1016/j.atherosclerosis.2011.09.003_bib0235) 1994; 94 Rogers (10.1016/j.atherosclerosis.2011.09.003_bib0030) 2003; 71 Simitsopoulou (10.1016/j.atherosclerosis.2011.09.003_bib0375) 2007; 51 Diacovo (10.1016/j.atherosclerosis.2011.09.003_bib0305) 1996; 88 Egger (10.1016/j.atherosclerosis.2011.09.003_bib0485) 2004; 429 Ouchi (10.1016/j.atherosclerosis.2011.09.003_bib0060) 2001; 103 O’Connell (10.1016/j.atherosclerosis.2011.09.003_bib0465) 2008; 205 Katz (10.1016/j.atherosclerosis.2011.09.003_bib0565) 1976; 58 Aslam (10.1016/j.atherosclerosis.2011.09.003_bib0310) 2007; 47 Li (10.1016/j.atherosclerosis.2011.09.003_bib0280) 1995; 84 Xue (10.1016/j.atherosclerosis.2011.09.003_bib0345) 2006; 317 Ordovas (10.1016/j.atherosclerosis.2011.09.003_bib0505) 2010; 7 Tsuchiya (10.1016/j.atherosclerosis.2011.09.003_bib0005) 1980; 26 Shanmugam (10.1016/j.atherosclerosis.2011.09.003_bib0480) 2008; 283 Braun (10.1016/j.atherosclerosis.2011.09.003_bib0210) 1999; 41 Menju (10.1016/j.atherosclerosis.2011.09.003_bib0135) 1989; 106 Simon (10.1016/j.atherosclerosis.2011.09.003_bib0300) 2000; 105 Dadgostar (10.1016/j.atherosclerosis.2011.09.003_bib0290) 2002; 99 Banka (10.1016/j.atherosclerosis.2011.09.003_bib0140) 1991; 32 Tone (10.1016/j.atherosclerosis.2011.09.003_bib0360) 2007; 8 Bartel (10.1016/j.atherosclerosis.2011.09.003_bib0435) 2004; 5 Whatling (10.1016/j.atherosclerosis.2011.09.003_bib0320) 2004; 45 Vickers (10.1016/j.atherosclerosis.2011.09.003_bib0445) 2010; 17 Unoki (10.1016/j.atherosclerosis.2011.09.003_bib0260) 2008; 32 Qiu (10.1016/j.atherosclerosis.2011.09.003_bib0370) 2007; 48 Shiffman (10.1016/j.atherosclerosis.2011.09.003_bib0315) 2000; 275 Zhang (10.1016/j.atherosclerosis.2011.09.003_bib0150) 2008; 102 Mancl (10.1016/j.atherosclerosis.2011.09.003_bib0600) 2005; 280 Mantovani (10.1016/j.atherosclerosis.2011.09.003_bib0105) 2004; 25 McDaniel (10.1016/j.atherosclerosis.2011.09.003_bib0415) 2004; 119 Fabunmi (10.1016/j.atherosclerosis.2011.09.003_bib0615) 1998; 83 Miao (10.1016/j.atherosclerosis.2011.09.003_bib0520) 2007; 282 Constant (10.1016/j.atherosclerosis.2011.09.003_bib0250) 2006; 49 Wang (10.1016/j.atherosclerosis.2011.09.003_bib0130) 1996; 271 Ragno (10.1016/j.atherosclerosis.2011.09.003_bib0400) 2001; 104 Hiltunen (10.1016/j.atherosclerosis.2011.09.003_bib0535) 2002; 7 McCaffrey (10.1016/j.atherosclerosis.2011.09.003_bib0495) 1997; 100 Li (10.1016/j.atherosclerosis.2011.09.003_bib0155) 2006; 98 Kunnari (10.1016/j.atherosclerosis.2011.09.003_bib0595) 2009; 157 Reyes Garcia (10.1016/j.atherosclerosis.2011.09.003_bib0240) 2010; 92 Mikita (10.1016/j.atherosclerosis.2011.09.003_bib0325) 2001; 276 He (10.1016/j.atherosclerosis.2011.09.003_bib0440) 2004; 5 Kritharides (10.1016/j.atherosclerosis.2011.09.003_bib0575) 1998; 18 Taganov (10.1016/j.atherosclerosis.2011.09.003_bib0455) 2006; 103 Wang (10.1016/j.atherosclerosis.2011.09.003_bib0340) 2006; 34 Chen (10.1016/j.atherosclerosis.2011.09.003_bib0350) 2007; 232 Cohen (10.1016/j.atherosclerosis.2011.09.003_bib0390) 2000; 275 Zhao (10.1016/j.atherosclerosis.2011.09.003_bib0585) 2005; 46 Tsuchiya (10.1016/j.atherosclerosis.2011.09.003_bib0010) 1982; 42 Zhao (10.1016/j.atherosclerosis.2011.09.003_bib0185) 2010; 107 Ren (10.1016/j.atherosclerosis.2011.09.003_bib0410) 2003; 990 Hulsmans (10.1016/j.atherosclerosis.2011.09.003_bib0450) 2011; 25 Massberg (10.1016/j.atherosclerosis.2011.09.003_bib0295) 2002; 196 Zhu (10.1016/j.atherosclerosis.2011.09.003_bib0215) 2000; 36 Szanto (10.1016/j.atherosclerosis.2011.09.003_bib0355) 2005; 67 Singal (10.1016/j.atherosclerosis.2011.09.003_bib0530) 1999; 93 Kaplanski (10.1016/j.atherosclerosis.2011.09.003_bib0170) 1998; 92 Schwende (10.1016/j.atherosclerosis.2011.09.003_bib0015) 1996; 59 Sonna (10.1016/j.atherosclerosis.2011.09.003_bib0365) 2006; 26 Mahmood Hussain (10.1016/j.atherosclerosis.2011.09.003_bib0190) 2000; 148 Barker (10.1016/j.atherosclerosis.2011.09.003_bib0380) 2005; 192 Fuentes (10.1016/j.atherosclerosis.2011.09.003_bib0285) 2002; 91 Constant (10.1016/j.atherosclerosis.2011.09.003_bib0255) 2008; 57 Gonsalves (10.1016/j.atherosclerosis.2011.09.003_bib0475) 2010; 185 Ioshikhes (10.1016/j.atherosclerosis.2011.09.003_bib0525) 2000; 26 Liang (10.1016/j.atherosclerosis.2011.09.003_bib0050) 2006; 281 Furman (10.1016/j.atherosclerosis.2011.09.003_bib0075) 2004; 37 Kohro (10.1016/j.atherosclerosis.2011.09.003_bib0425) 2004; 11 Altieri (10.1016/j.atherosclerosis.2011.09.003_bib0115) 1988; 263 Burke (10.1016/j.atherosclerosis.2011.09.003_bib0040) 2002; 72 Qin (10.1016/j.atherosclerosis.2011.09.003_bib0220) 2008; 150 Sharif (10.1016/j.atherosclerosis.2011.09.003_bib0420) 2007; 8 Cousins (10.1016/j.atherosclerosis.2011.09.003_bib0035) 2003; 100 Han (10.1016/j.atherosclerosis.2011.09.003_bib0080) 2005; 111 Gupta (10.1016/j.atherosclerosis.2011.09.003_bib0160) 2005; 97 Ambros (10.1016/j.atherosclerosis.2011.09.003_bib0430) 2004; 431 Glick (10.1016/j.atherosclerosis.2011.09.003_bib0570) 1983; 258 Lund (10.1016/j.atherosclerosis.2011.09.003_bib0540) 2004; 279 Lee (10.1016/j.atherosclerosis.2011.09.003_bib0055) 2005; 280 Ross (10.1016/j.atherosclerosis.2011.09.003_bib0490) 1993; 362 Maess (10.1016/j.atherosclerosis.2011.09.003_bib0095) 2011; 2011 Schnoor (10.1016/j.atherosclerosis.2011.09.003_bib0090) 2009; 344 Dowds (10.1016/j.atherosclerosis.2011.09.003_bib0045) 2004; 279 Handy (10.1016/j.atherosclerosis.2011.09.003_bib0500) 2011; 123 Sneddon (10.1016/j.atherosclerosis.2011.09.003_bib0180) 2006; 1761 Johnson (10.1016/j.atherosclerosis.2011.09.003_bib0630) 2003; 162 Llaverias (10.1016/j.atherosclerosis.2011.09.003_bib0330) 2004; 318 Pollard (10.1016/j.atherosclerosis.2011.09.003_bib0405) 2004; 6 Guzzo (10.1016/j.atherosclerosis.2011.09.003_bib0625) 2010; 285 Mangan (10.1016/j.atherosclerosis.2011.09.003_bib0550) 1991; 147 Goldberg (10.1016/j.atherosclerosis.2011.09.003_bib0195) 1996; 37 Keuper (10.1016/j.atherosclerosis.2011.09.003_bib0270) 2011; 339 Gaffney (10.1016/j.atherosclerosis.2011.09.003_bib0125) 1986; 39 Altieri (10.1016/j.atherosclerosis.2011.09.003_bib0100) 1988; 141 Kawakami (10.1016/j.atherosclerosis.2011.09.003_bib0165) 2006; 114 Zeyda (10.1016/j.atherosclerosis.2011.09.003_bib0245) 2007; 112 Cai (10.1016/j.atherosclerosis.2011.09.003_bib0200) 2004; 287 Stout (10.1016/j.atherosclerosis.2011.09.003_bib0275) 1993; 150 Okamoto (10.1016/j.atherosclerosis.2011.09.003_bib0065) 2008; 102 Carayol (10.1016/j.atherosclerosis.2011.09.003_bib0335) 2006; 281 Gee (10.1016/j.atherosclerosis.2011.09.003_bib0590) 2003; 278 Halvorsen (10.1016/j.atherosclerosis.2011.09.003_bib0610) 2005; 46 Graham (10.1016/j.atherosclerosis.2011.09.003_bib0145) 1996; 120 Spencer (10.1016/j.atherosclerosis.2011.09.003_bib0110) 2010; 299 Kudrin (10.1016/j.atherosclerosis.2011.09.003_bib0620) 2006; 281 Krakauer (10.1016/j.atherosclerosis.2011.09.003_bib0175) 1994; 177 Mangan (10.1016/j.atherosclerosis.2011.09.003_bib0545) 1991; 146 Motiwala (10.1016/j.atherosclerosis.2011.09.003_bib0395) 2006; 74 Persson (10.1016/j.atherosclerosis.2011.09.003_bib0580) 2007; 363 Adib-Conquy (10.1016/j.atherosclerosis.2011.09.003_bib0555) 2002; 277 Wabitsch (10.1016/j.atherosclerosis.2011.09.003_bib0265) 2001; 25 Lada (10.1016/j.atherosclerosis.2011.09.003_bib0560) 2002; 43 Rutherford (10.1016/j.atherosclerosis.2011.09.003_bib0225) 1997; 130 Fraga (10.1016/j.atherosclerosis.2011.09.003_bib0515) 2005; 37 Li (10.1016/j.atherosclerosis.2011.09.003_bib0470) 2011; 186 Lu (10.1016/j.atherosclerosis.2011.09.003_bib0605) 2009; 284 Iwamoto (10.1016/j.atherosclerosis.2011.09.003_bib0070) 2007; 101
References_xml	– volume: 148 start-page: 1 year: 2000 end-page: 15 ident: bib0190 article-title: A proposed model for the assembly of chylomicrons publication-title: Atherosclerosis – volume: 362 start-page: 801 year: 1993 end-page: 809 ident: bib0490 article-title: The pathogenesis of atherosclerosis: a perspective for the 1990s publication-title: Nature – volume: 282 start-page: 13854 year: 2007 end-page: 13863 ident: bib0520 article-title: Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes publication-title: J Biol Chem – volume: 429 start-page: 457 year: 2004 end-page: 463 ident: bib0485 article-title: Epigenetics in human disease and prospects for epigenetic therapy publication-title: Nature – volume: 84 start-page: 571 year: 1995 end-page: 576 ident: bib0280 article-title: Contact-dependent stimulation of monocytic cells and neutrophils by stimulated human T-cell clones publication-title: Immunology – volume: 102 start-page: 218 year: 2008 end-page: 225 ident: bib0065 article-title: Adiponectin inhibits the production of CXC receptor 3 chemokine ligands in macrophages and reduces T-lymphocyte recruitment in atherogenesis publication-title: Circ Res – volume: 26 start-page: 91 year: 2006 end-page: 98 ident: bib0365 article-title: Effect of moderate hypothermia on gene expression by THP-1 cells: a DNA microarray study publication-title: Physiol Genomics – volume: 344 start-page: 109 year: 2009 end-page: 115 ident: bib0090 article-title: Efficient non-viral transfection of THP-1 cells publication-title: J Immunol Methods – volume: 285 start-page: 24404 year: 2010 end-page: 24411 ident: bib0625 article-title: Interleukin-27 induces a STAT1/3- and NF-κB-dependent proinflammatory cytokine profile in human monocytes publication-title: J Biol Chem – volume: 258 start-page: 13425 year: 1983 end-page: 13430 ident: bib0570 article-title: Cellular cholesteryl ester clearance. Relationship to the physical state of cholesteryl ester inclusions publication-title: J Biol Chem – volume: 75 start-page: 3506 year: 2007 end-page: 3515 ident: bib0385 article-title: abrogates gamma interferon-induced gene expression in human macrophages from a global perspective publication-title: Infect Immun – volume: 284 start-page: 34839 year: 2009 end-page: 34848 ident: bib0605 article-title: Leukocyte Ig-like receptor B4 (LILRB4) is a potent inhibitor of FcγRI-mediated monocyte activation via dephosphorylation of multiple kinases publication-title: J Biol Chem – volume: 103 start-page: 1057 year: 2001 end-page: 1063 ident: bib0060 article-title: Adipocyte-derived plasma protein: adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages publication-title: Circulation – volume: 2011 year: 2011 ident: bib0095 article-title: Improved protocol for efficient nonviral transfection of premature THP-1 macrophages publication-title: Cold Spring Harb Protoc – volume: 100 start-page: 6952 year: 2003 end-page: 6957 ident: bib0035 article-title: A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells publication-title: Proc Natl Acad Sci USA – volume: 47 start-page: 22 year: 1991 end-page: 31 ident: bib0025 article-title: The human leukemia cell line, THP-1: a multifacetted model for the study of monocyte–macrophage differentiation publication-title: Experientia – volume: 162 start-page: 283 year: 2003 end-page: 291 ident: bib0630 article-title: Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression publication-title: Am J Pathol – volume: 37 start-page: 71 year: 2004 end-page: 85 ident: bib0075 article-title: Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: specific induction of the promoter in human macrophages by oxidized low-density lipoproteins publication-title: Free Radic Biol Med – volume: 46 start-page: 211 year: 2005 end-page: 219 ident: bib0610 article-title: Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms publication-title: J Lipid Res – volume: 318 start-page: 265 year: 2004 end-page: 274 ident: bib0330 article-title: Atorvastatin reduces CD68: FABP4, and HBP expression in oxLDL-treated human macrophages publication-title: Biochem Biophys Res Commun – volume: 37 start-page: 391 year: 2005 end-page: 400 ident: bib0515 article-title: Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer publication-title: Nat Genet – volume: 106 start-page: 505 year: 1989 end-page: 510 ident: bib0135 article-title: Expression of the apolipoprotein E gene in a human macrophage-like cell line: THP-1 publication-title: J Biochem – volume: 157 start-page: 57 year: 2009 end-page: 63 ident: bib0595 article-title: The expression of human resistin in different leucocyte lineages is modulated by LPS and TNF alpha publication-title: Regul Pept – volume: 104 start-page: 1604 year: 2007 end-page: 1609 ident: bib0460 article-title: MicroRNA-155 is induced during the macrophage inflammatory response publication-title: Proc Natl Acad Sci USA – volume: 123 start-page: 2145 year: 2011 end-page: 2156 ident: bib0500 article-title: Epigenetic modifications: basic mechanisms and role in cardiovascular disease publication-title: Circulation – volume: 279 start-page: 51897 year: 2004 end-page: 51907 ident: bib0085 article-title: PAN1/NALP2/PYPAF2: an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages publication-title: J Biol Chem – volume: 105 start-page: 650 year: 2002 end-page: 655 ident: bib0230 article-title: Monocyte/macrophage regulation of vascular calcification in vitro publication-title: Circulation – volume: 74 start-page: 6046 year: 2006 end-page: 6056 ident: bib0395 article-title: Comparative transcriptional analysis of human macrophages exposed to animal and human isolates of publication-title: Infect Immun – volume: 185 start-page: 6253 year: 2010 end-page: 6264 ident: bib0475 article-title: Endothelin-1-induced macrophage inflammatory protein-1 beta expression in monocytic cells involves hypoxia-inducible factor-1 alpha and AP-1 and is negatively regulated by microRNA-195 publication-title: J Immunol – volume: 46 start-page: 2114 year: 2005 end-page: 2121 ident: bib0585 article-title: Redistribution of macrophage cholesteryl ester hydrolase from cytoplasm to lipid droplets upon lipid loading publication-title: J Lipid Res – volume: 83 start-page: 270 year: 1998 end-page: 278 ident: bib0615 article-title: Expression of tissue inhibitor of metalloproteinases-3 in human atheroma and regulation in lesion-associated cells: a potential protective mechanism in plaque stability publication-title: Circ Res – volume: 102 start-page: 250 year: 2008 end-page: 256 ident: bib0150 article-title: Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet publication-title: Circ Res – volume: 32 start-page: 902 year: 2008 end-page: 911 ident: bib0260 article-title: Macrophages regulate tumor necrosis factor-alpha expression in adipocytes through the secretion of matrix metalloproteinase-3 publication-title: Int J Obes (Lond) – volume: 275 start-page: 37324 year: 2000 end-page: 37332 ident: bib0315 article-title: Large scale gene expression analysis of cholesterol-loaded macrophages publication-title: J Biol Chem – volume: 11 start-page: 88 year: 2004 end-page: 97 ident: bib0425 article-title: A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage publication-title: J Atheroscler Thromb – volume: 6 start-page: 639 year: 2004 end-page: 650 ident: bib0405 article-title: Differential post-transcriptional activation of human phagocytes by different publication-title: Cell Microbiol – volume: 990 start-page: 701 year: 2003 end-page: 713 ident: bib0410 article-title: Comparative DNA microarray analysis of host cell transcriptional responses to infection by publication-title: Ann N Y Acad Sci – volume: 18 start-page: 1589 year: 1998 end-page: 1599 ident: bib0575 article-title: Cholesterol metabolism and efflux in human THP-1 macrophages publication-title: Arterioscler Thromb Vasc Biol – volume: 186 start-page: 2552 year: 2011 end-page: 2560 ident: bib0470 article-title: Role of microRNA-214-targeting phosphatase and tensin homolog in advanced glycation end product-induced apoptosis delay in monocytes publication-title: J Immunol – volume: 50 start-page: S335 year: 2009 end-page: S339 ident: bib0510 article-title: Diabetes and atherosclerosis: is there a role for hyperglycemia? publication-title: J Lipid Res – volume: 150 start-page: 1 year: 2008 end-page: 6 ident: bib0220 article-title: Newly developed angiotensin II-infused experimental models in vascular biology publication-title: Regul Pept – volume: 72 start-page: 417 year: 2002 end-page: 428 ident: bib0040 article-title: Macrophages in gene therapy: cellular delivery vehicles and in vivo targets publication-title: J Leukoc Biol – volume: 112 start-page: 61 year: 2007 end-page: 67 ident: bib0245 article-title: Adipose tissue macrophages publication-title: Immunol Lett – volume: 146 start-page: 1541 year: 1991 end-page: 1546 ident: bib0545 article-title: Lipopolysaccharide: tumor necrosis factor-alpha, and IL-1 beta prevent programmed cell death (apoptosis) in human peripheral blood monocytes publication-title: J Immunol – volume: 39 start-page: 409 year: 1986 end-page: 421 ident: bib0125 article-title: Characterization of a colony-stimulating factor produced by the human monocytic leukemia cell line: THP-1 publication-title: J Leukoc Biol – volume: 59 start-page: 555 year: 1996 end-page: 561 ident: bib0015 article-title: Differences in the state of differentiation of THP-1 cells induced by phorbol ester and 1,25-dihydroxyvitamin D3 publication-title: J Leukoc Biol – volume: 283 start-page: 36221 year: 2008 end-page: 36233 ident: bib0480 article-title: Distinct roles of heterogeneous nuclear ribonuclear protein K and microRNA-16 in cyclooxygenase-2 RNA stability induced by S100 b: a ligand of the receptor for advanced glycation end products publication-title: J Biol Chem – volume: 45 start-page: 1768 year: 2004 end-page: 1776 ident: bib0320 article-title: Effect of macrophage differentiation and exposure to mildly oxidized LDL on the proteolytic repertoire of THP-1 monocytes publication-title: J Lipid Res – volume: 17 start-page: 150 year: 2010 end-page: 155 ident: bib0445 article-title: MicroRNAs in atherosclerosis and lipoprotein metabolism publication-title: Curr Opin Endocrinol Diabetes Obes – volume: 279 start-page: 21924 year: 2004 end-page: 21928 ident: bib0045 article-title: Cryopyrin-induced interleukin 1 beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC publication-title: J Biol Chem – volume: 114 start-page: 681 year: 2006 end-page: 687 ident: bib0165 article-title: Apolipoprotein CIII induces expression of vascular cell adhesion molecule-1 in vascular endothelial cells and increases adhesion of monocytic cells publication-title: Circulation – volume: 25 start-page: 677 year: 2004 end-page: 686 ident: bib0105 article-title: The chemokine system in diverse forms of macrophage activation and polarization publication-title: Trends Immunol – volume: 5 start-page: e8668 year: 2010 ident: bib0020 article-title: The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages publication-title: PLoS ONE – volume: 51 start-page: 1048 year: 2007 end-page: 1054 ident: bib0375 article-title: Expression of immunomodulatory genes in human monocytes induced by voriconazole in the presence of publication-title: Antimicrob Agents Chemother – volume: 93 start-page: 4059 year: 1999 end-page: 4070 ident: bib0530 article-title: DNA methylation publication-title: Blood – volume: 58 start-page: 200 year: 1976 end-page: 211 ident: bib0565 article-title: Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques publication-title: J Clin Invest – volume: 7 start-page: 510 year: 2010 end-page: 519 ident: bib0505 article-title: Epigenetics and cardiovascular disease publication-title: Nat Rev Cardiol – volume: 92 start-page: 405 year: 2010 end-page: 406 ident: bib0240 article-title: Osteocalcin and atherosclerosis: a complex relationship publication-title: Diabetes Res Clin Pract – volume: 7 start-page: 5 year: 2002 end-page: 11 ident: bib0535 article-title: DNA hypomethylation and methyltransferase expression in atherosclerotic lesions publication-title: Vasc Med – volume: 25 start-page: 2515 year: 2011 end-page: 2527 ident: bib0450 article-title: MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis publication-title: Faseb J – volume: 26 start-page: 61 year: 2000 end-page: 63 ident: bib0525 article-title: Large-scale human promoter mapping using CpG islands publication-title: Nat Genet – volume: 119 start-page: 99 year: 2004 end-page: 103 ident: bib0415 article-title: Use of cDNA microarrays to analyze responses to pneumococcal virulence factors publication-title: Indian J Med Res – volume: 232 start-page: 488 year: 2007 end-page: 494 ident: bib0350 article-title: Retinoic acid regulates CD1d gene expression at the transcriptional level in human and rodent monocytic cells publication-title: Exp Biol Med (Maywood) – volume: 271 start-page: 8837 year: 1996 end-page: 8842 ident: bib0130 article-title: Interleukin 8 is induced by cholesterol loading of macrophages and expressed by macrophage foam cells in human atheroma publication-title: J Biol Chem – volume: 98 start-page: 642 year: 2006 end-page: 650 ident: bib0155 article-title: Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC publication-title: Circ Res – volume: 196 start-page: 887 year: 2002 end-page: 896 ident: bib0295 article-title: A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation publication-title: J Exp Med – volume: 91 start-page: 681 year: 2002 end-page: 688 ident: bib0285 article-title: Cooperation between secretory phospholipase A2 and TNF-receptor superfamily signaling: implications for the inflammatory response in atherogenesis publication-title: Circ Res – volume: 120 start-page: 135 year: 1996 end-page: 145 ident: bib0145 article-title: Impaired mobilisation of cholesterol from stored cholesteryl esters in human (THP-1) macrophages publication-title: Atherosclerosis – volume: 275 start-page: 11181 year: 2000 end-page: 11190 ident: bib0390 article-title: Monitoring cellular responses to publication-title: J Biol Chem – volume: 111 start-page: 1439 year: 2005 end-page: 1447 ident: bib0080 article-title: HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo publication-title: Circulation – volume: 105 start-page: 293 year: 2000 end-page: 300 ident: bib0300 article-title: Decreased neointimal formation in Mac-1(−/−) mice reveals a role for inflammation in vascular repair after angioplasty publication-title: J Clin Invest – volume: 5 start-page: 396 year: 2004 end-page: 400 ident: bib0435 article-title: Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs publication-title: Nat Rev Genet – volume: 150 start-page: 5330 year: 1993 end-page: 5337 ident: bib0275 article-title: T cell-macrophage cognate interaction in the activation of macrophage effector function by Th2 cells publication-title: J Immunol – volume: 25 start-page: 8 year: 2001 end-page: 15 ident: bib0265 article-title: Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation publication-title: Int J Obes Relat Metab Disord – volume: 8 start-page: 1 year: 2007 ident: bib0420 article-title: Transcriptional profiling of the LPS induced NF-kappaB response in macrophages publication-title: BMC Immunol – volume: 205 start-page: 585 year: 2008 end-page: 594 ident: bib0465 article-title: Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder publication-title: J Exp Med – volume: 100 start-page: 2182 year: 1997 end-page: 2188 ident: bib0495 article-title: Genomic instability in the type II TGF-beta1 receptor gene in atherosclerotic and restenotic vascular cells publication-title: J Clin Invest – volume: 103 start-page: 12481 year: 2006 end-page: 12486 ident: bib0455 article-title: NF-kappaB-dependent induction of microRNA miR-146: an inhibitor targeted to signaling proteins of innate immune responses publication-title: Proc Natl Acad Sci USA – volume: 280 start-page: 21078 year: 2005 end-page: 21090 ident: bib0600 article-title: Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms publication-title: J Biol Chem – volume: 88 start-page: 146 year: 1996 end-page: 157 ident: bib0305 article-title: Neutrophil rolling: arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18 publication-title: Blood – volume: 281 start-page: 29641 year: 2006 end-page: 29651 ident: bib0620 article-title: Human macrophage migration inhibitory factor publication-title: J Biol Chem – volume: 317 start-page: 53 year: 2006 end-page: 60 ident: bib0345 article-title: Anti-inflammatory activity in vitro and in vivo of the protein farnesyltransferase inhibitor tipifarnib publication-title: J Pharmacol Exp Ther – volume: 67 start-page: 1935 year: 2005 end-page: 1943 ident: bib0355 article-title: Retinoids potentiate peroxisome proliferator-activated receptor gamma action in differentiation: gene expression, and lipid metabolic processes in developing myeloid cells publication-title: Mol Pharmacol – volume: 37 start-page: 693 year: 1996 end-page: 707 ident: bib0195 article-title: Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis publication-title: J Lipid Res – volume: 278 start-page: 37275 year: 2003 end-page: 37287 ident: bib0590 article-title: Tumor necrosis factor-α induces functionally active hyaluronan-adhesive CD44 by activating sialidase through p38 mitogen-activated protein kinase in lipopolysaccharide-stimulated human monocytic cells publication-title: J Biol Chem – volume: 101 start-page: 156 year: 2007 end-page: 165 ident: bib0070 article-title: ATP-binding cassette transporter A1 gene transcription is downregulated by activator protein 2 alpha. Doxazosin inhibits activator protein 2 alpha and increases high-density lipoprotein biogenesis independent of alpha1-adrenoceptor blockade publication-title: Circ Res – volume: 36 start-page: 152 year: 2000 end-page: 161 ident: bib0215 article-title: Interaction between monocytes and vascular smooth muscle cells enhances matrix metalloproteinase-1 production publication-title: J Cardiovasc Pharmacol – volume: 34 start-page: 3044 year: 2006 end-page: 3056 ident: bib0340 article-title: Nitric oxide activation of Erk1/2 regulates the stability and translation of mRNA transcripts containing CU-rich elements publication-title: Nucleic Acids Res – volume: 57 start-page: 465 year: 2008 end-page: 472 ident: bib0255 article-title: The antiadipogenic effect of macrophage-conditioned medium depends on ERK1/2 activation publication-title: Metabolism – volume: 299 start-page: E1016 year: 2010 end-page: E1027 ident: bib0110 article-title: Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation publication-title: Am J Physiol Endocrinol Metab – volume: 48 start-page: 385 year: 2007 end-page: 394 ident: bib0370 article-title: Suppression of endothelial or lipoprotein lipase in THP-1 macrophages attenuates proinflammatory cytokine secretion publication-title: J Lipid Res – volume: 91 start-page: 9 year: 2002 end-page: 16 ident: bib0205 article-title: Induction of bone-type alkaline phosphatase in human vascular smooth muscle cells: roles of tumor necrosis factor-alpha and oncostatin M derived from macrophages publication-title: Circ Res – volume: 5 start-page: 522 year: 2004 end-page: 531 ident: bib0440 article-title: MicroRNAs: small RNAs with a big role in gene regulation publication-title: Nat Rev Genet – volume: 263 start-page: 7007 year: 1988 end-page: 7015 ident: bib0115 article-title: The saturable high affinity association of factor X to ADP-stimulated monocytes defines a novel function of the Mac-1 receptor publication-title: J Biol Chem – volume: 104 start-page: 99 year: 2001 end-page: 108 ident: bib0400 article-title: Changes in gene expression in macrophages infected with publication-title: Immunology – volume: 141 start-page: 2656 year: 1988 end-page: 2660 ident: bib0100 article-title: A monoclonal antibody reacting with distinct adhesion molecules defines a transition in the functional state of the receptor CD11 b/CD18 (Mac-1) publication-title: J Immunol – volume: 32 start-page: 35 year: 1991 end-page: 43 ident: bib0140 article-title: THP-1 cells form foam cells in response to coculture with lipoproteins but not platelets publication-title: J Lipid Res – volume: 276 start-page: 45729 year: 2001 end-page: 45739 ident: bib0325 article-title: Oxidized low density lipoprotein exposure alters the transcriptional response of macrophages to inflammatory stimulus publication-title: J Biol Chem – volume: 1761 start-page: 793 year: 2006 end-page: 801 ident: bib0180 article-title: Cytokine-induced monocyte adhesion to endothelial cells involves platelet-activating factor: suppression by conjugated linoleic acid publication-title: Biochim Biophys Acta – volume: 177 start-page: 207 year: 1994 end-page: 213 ident: bib0175 article-title: A sensitive ELISA for measuring the adhesion of leukocytic cells to human endothelial cells publication-title: J Immunol Methods – volume: 277 start-page: 27927 year: 2002 end-page: 27934 ident: bib0555 article-title: Gamma interferon and granulocyte/monocyte colony-stimulating factor prevent endotoxin tolerance in human monocytes by promoting interleukin-1 receptor-associated kinase expression and its association to MyD88 and not by modulating TLR4 expression publication-title: J Biol Chem – volume: 339 start-page: 105 year: 2011 end-page: 113 ident: bib0270 article-title: An inflammatory micro-environment promotes human adipocyte apoptosis publication-title: Mol Cell Endocrinol – volume: 26 start-page: 171 year: 1980 end-page: 176 ident: bib0005 article-title: Establishment and characterization of a human acute monocytic leukemia cell line (THP-1) publication-title: Int J Cancer – volume: 8 start-page: 45 year: 2007 end-page: 50 ident: bib0360 article-title: Changes of gene expression profiles in macrophages stimulated by angiotensin II—angiotensin II induces MCP-2 through AT1-receptor publication-title: J Renin Angiotensin Aldosterone Syst – volume: 41 start-page: 395 year: 1999 end-page: 401 ident: bib0210 article-title: Cellular adhesion molecules on vascular smooth muscle cells publication-title: Cardiovasc Res – volume: 47 start-page: 2161 year: 2007 end-page: 2168 ident: bib0310 article-title: Platelet and red blood cell phagocytosis kinetics are differentially controlled by phosphatase activity within mononuclear cells publication-title: Transfusion – volume: 147 start-page: 3408 year: 1991 end-page: 3412 ident: bib0550 article-title: Differential regulation of human monocyte programmed cell death (apoptosis) by chemotactic factors and pro-inflammatory cytokines publication-title: J Immunol – volume: 281 start-page: 27526 year: 2006 end-page: 27538 ident: bib0050 article-title: Monocyte differentiation up-regulates the expression of the lysosomal sialidase: Neu1, and triggers its targeting to the plasma membrane via major histocompatibility complex class II-positive compartments publication-title: J Biol Chem – volume: 94 start-page: 1597 year: 1994 end-page: 1604 ident: bib0235 article-title: Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis publication-title: J Clin Invest – volume: 99 start-page: 1497 year: 2002 end-page: 1502 ident: bib0290 article-title: Cooperation of multiple signaling pathways in CD40-regulated gene expression in B lymphocytes publication-title: Proc Natl Acad Sci USA – volume: 279 start-page: 29147 year: 2004 end-page: 29154 ident: bib0540 article-title: DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E publication-title: J Biol Chem – volume: 49 start-page: 1402 year: 2006 end-page: 1411 ident: bib0250 article-title: Macrophage-conditioned medium inhibits the differentiation of 3 T3-L1 and human abdominal preadipocytes publication-title: Diabetologia – volume: 42 start-page: 1530 year: 1982 end-page: 1536 ident: bib0010 article-title: Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester publication-title: Cancer Res – volume: 92 start-page: 1259 year: 1998 end-page: 1267 ident: bib0170 article-title: Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106) publication-title: Blood – volume: 363 start-page: 1020 year: 2007 end-page: 1026 ident: bib0580 article-title: Perilipin and adipophilin expression in lipid loaded macrophages publication-title: Biochem Biophys Res Commun – volume: 97 start-page: 236 year: 2005 end-page: 243 ident: bib0160 article-title: Inhibition of lipopolysaccharide-induced inflammatory responses by an apolipoprotein AI mimetic peptide publication-title: Circ Res – volume: 107 start-page: 501 year: 2010 end-page: 511 ident: bib0185 article-title: Deficiency of the NR4 A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis publication-title: Circ Res – volume: 130 start-page: 45 year: 1997 end-page: 51 ident: bib0225 article-title: Substantial inhibition of neo-intimal response to balloon injury in the rat carotid artery using a combination of antibodies to platelet-derived growth factor-BB and basic fibroblast growth factor publication-title: Atherosclerosis – volume: 192 start-page: 901 year: 2005 end-page: 912 ident: bib0380 article-title: Coculture of THP-1 human mononuclear cells with publication-title: J Infect Dis – volume: 281 start-page: 31142 year: 2006 end-page: 31151 ident: bib0335 article-title: A dominant function of IKK/NF-kappaB signaling in global lipopolysaccharide-induced gene expression publication-title: J Biol Chem – volume: 431 start-page: 350 year: 2004 end-page: 355 ident: bib0430 article-title: The functions of animal microRNAs publication-title: Nature – volume: 280 start-page: 7845 year: 2005 end-page: 7853 ident: bib0055 article-title: The amyloid-beta peptide suppresses transforming growth factor-beta1-induced matrix metalloproteinase-2 production via Smad7 expression in human monocytic THP-1 cells publication-title: J Biol Chem – volume: 43 start-page: 618 year: 2002 end-page: 628 ident: bib0560 article-title: Triglyceride depletion in THP-1 cells alters cholesteryl ester physical state and cholesterol efflux publication-title: J Lipid Res – volume: 287 start-page: C707 year: 2004 end-page: C714 ident: bib0200 article-title: Growth factors induce monocyte binding to vascular smooth muscle cells: implications for monocyte retention in atherosclerosis publication-title: Am J Physiol Cell Physiol – volume: 71 start-page: 2087 year: 2003 end-page: 2094 ident: bib0030 article-title: Pneumolysin-dependent and -independent gene expression identified by cDNA microarray analysis of THP-1 human mononuclear cells stimulated by publication-title: Infect Immun – volume: 75 start-page: 3506 issue: 7 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0385 article-title: Leishmania major abrogates gamma interferon-induced gene expression in human macrophages from a global perspective publication-title: Infect Immun doi: 10.1128/IAI.00277-07 – volume: 26 start-page: 91 issue: 1 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0365 article-title: Effect of moderate hypothermia on gene expression by THP-1 cells: a DNA microarray study publication-title: Physiol Genomics doi: 10.1152/physiolgenomics.00296.2005 – volume: 11 start-page: 88 issue: 2 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0425 article-title: A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage publication-title: J Atheroscler Thromb doi: 10.5551/jat.11.88 – volume: 88 start-page: 146 issue: 1 year: 1996 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0305 article-title: Neutrophil rolling: arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18 publication-title: Blood doi: 10.1182/blood.V88.1.146.146 – volume: 192 start-page: 901 issue: 5 year: 2005 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0380 article-title: Coculture of THP-1 human mononuclear cells with Candida albicans results in pronounced changes in host gene expression publication-title: J Infect Dis doi: 10.1086/432487 – volume: 50 start-page: S335 issue: Suppl. year: 2009 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0510 article-title: Diabetes and atherosclerosis: is there a role for hyperglycemia? publication-title: J Lipid Res doi: 10.1194/jlr.R800059-JLR200 – volume: 232 start-page: 488 issue: 4 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0350 article-title: Retinoic acid regulates CD1d gene expression at the transcriptional level in human and rodent monocytic cells publication-title: Exp Biol Med (Maywood) – volume: 431 start-page: 350 issue: 7006 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0430 article-title: The functions of animal microRNAs publication-title: Nature doi: 10.1038/nature02871 – volume: 104 start-page: 1604 issue: 5 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0460 article-title: MicroRNA-155 is induced during the macrophage inflammatory response publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0610731104 – volume: 101 start-page: 156 issue: 2 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0070 article-title: ATP-binding cassette transporter A1 gene transcription is downregulated by activator protein 2 alpha. Doxazosin inhibits activator protein 2 alpha and increases high-density lipoprotein biogenesis independent of alpha1-adrenoceptor blockade publication-title: Circ Res doi: 10.1161/CIRCRESAHA.107.151746 – volume: 45 start-page: 1768 issue: 9 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0320 article-title: Effect of macrophage differentiation and exposure to mildly oxidized LDL on the proteolytic repertoire of THP-1 monocytes publication-title: J Lipid Res doi: 10.1194/jlr.M400195-JLR200 – volume: 317 start-page: 53 issue: 1 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0345 article-title: Anti-inflammatory activity in vitro and in vivo of the protein farnesyltransferase inhibitor tipifarnib publication-title: J Pharmacol Exp Ther doi: 10.1124/jpet.105.095976 – volume: 147 start-page: 3408 issue: 10 year: 1991 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0550 article-title: Differential regulation of human monocyte programmed cell death (apoptosis) by chemotactic factors and pro-inflammatory cytokines publication-title: J Immunol doi: 10.4049/jimmunol.147.10.3408 – volume: 97 start-page: 236 issue: 3 year: 2005 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0160 article-title: Inhibition of lipopolysaccharide-induced inflammatory responses by an apolipoprotein AI mimetic peptide publication-title: Circ Res doi: 10.1161/01.RES.0000176530.66400.48 – volume: 94 start-page: 1597 issue: 4 year: 1994 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0235 article-title: Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis publication-title: J Clin Invest doi: 10.1172/JCI117501 – volume: 103 start-page: 1057 issue: 8 year: 2001 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0060 article-title: Adipocyte-derived plasma protein: adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages publication-title: Circulation doi: 10.1161/01.CIR.103.8.1057 – volume: 42 start-page: 1530 issue: 4 year: 1982 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0010 article-title: Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester publication-title: Cancer Res – volume: 26 start-page: 171 issue: 2 year: 1980 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0005 article-title: Establishment and characterization of a human acute monocytic leukemia cell line (THP-1) publication-title: Int J Cancer doi: 10.1002/ijc.2910260208 – volume: 37 start-page: 693 issue: 4 year: 1996 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0195 article-title: Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis publication-title: J Lipid Res doi: 10.1016/S0022-2275(20)37569-6 – volume: 98 start-page: 642 issue: 5 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0155 article-title: Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC publication-title: Circ Res doi: 10.1161/01.RES.0000207394.39249.fc – volume: 25 start-page: 2515 issue: 8 year: 2011 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0450 article-title: MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis publication-title: Faseb J doi: 10.1096/fj.11-181149 – volume: 157 start-page: 57 issue: 1–3 year: 2009 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0595 article-title: The expression of human resistin in different leucocyte lineages is modulated by LPS and TNF alpha publication-title: Regul Pept doi: 10.1016/j.regpep.2009.05.002 – volume: 92 start-page: 1259 issue: 4 year: 1998 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0170 article-title: Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106) publication-title: Blood doi: 10.1182/blood.V92.4.1259 – volume: 429 start-page: 457 issue: 6990 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0485 article-title: Epigenetics in human disease and prospects for epigenetic therapy publication-title: Nature doi: 10.1038/nature02625 – volume: 34 start-page: 3044 issue: 10 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0340 article-title: Nitric oxide activation of Erk1/2 regulates the stability and translation of mRNA transcripts containing CU-rich elements publication-title: Nucleic Acids Res doi: 10.1093/nar/gkl386 – volume: 39 start-page: 409 issue: 4 year: 1986 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0125 article-title: Characterization of a colony-stimulating factor produced by the human monocytic leukemia cell line: THP-1 publication-title: J Leukoc Biol doi: 10.1002/jlb.39.4.409 – volume: 114 start-page: 681 issue: 7 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0165 article-title: Apolipoprotein CIII induces expression of vascular cell adhesion molecule-1 in vascular endothelial cells and increases adhesion of monocytic cells publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.106.622514 – volume: 46 start-page: 211 issue: 2 year: 2005 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0610 article-title: Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms publication-title: J Lipid Res doi: 10.1194/jlr.M400324-JLR200 – volume: 84 start-page: 571 issue: 4 year: 1995 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0280 article-title: Contact-dependent stimulation of monocytic cells and neutrophils by stimulated human T-cell clones publication-title: Immunology – volume: 49 start-page: 1402 issue: 6 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0250 article-title: Macrophage-conditioned medium inhibits the differentiation of 3 T3-L1 and human abdominal preadipocytes publication-title: Diabetologia doi: 10.1007/s00125-006-0253-0 – volume: 196 start-page: 887 issue: 7 year: 2002 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0295 article-title: A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation publication-title: J Exp Med doi: 10.1084/jem.20012044 – volume: 74 start-page: 6046 issue: 11 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0395 article-title: Comparative transcriptional analysis of human macrophages exposed to animal and human isolates of Mycobacterium avium subspecies paratuberculosis with diverse genotypes publication-title: Infect Immun doi: 10.1128/IAI.00326-06 – volume: 362 start-page: 801 issue: 6423 year: 1993 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0490 article-title: The pathogenesis of atherosclerosis: a perspective for the 1990s publication-title: Nature doi: 10.1038/362801a0 – volume: 105 start-page: 293 issue: 3 year: 2000 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0300 article-title: Decreased neointimal formation in Mac-1(−/−) mice reveals a role for inflammation in vascular repair after angioplasty publication-title: J Clin Invest doi: 10.1172/JCI7811 – volume: 102 start-page: 218 issue: 2 year: 2008 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0065 article-title: Adiponectin inhibits the production of CXC receptor 3 chemokine ligands in macrophages and reduces T-lymphocyte recruitment in atherogenesis publication-title: Circ Res doi: 10.1161/CIRCRESAHA.107.164988 – volume: 130 start-page: 45 issue: 1–2 year: 1997 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0225 article-title: Substantial inhibition of neo-intimal response to balloon injury in the rat carotid artery using a combination of antibodies to platelet-derived growth factor-BB and basic fibroblast growth factor publication-title: Atherosclerosis doi: 10.1016/S0021-9150(96)06042-X – volume: 5 start-page: 522 issue: 7 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0440 article-title: MicroRNAs: small RNAs with a big role in gene regulation publication-title: Nat Rev Genet doi: 10.1038/nrg1379 – volume: 37 start-page: 391 issue: 4 year: 2005 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0515 article-title: Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer publication-title: Nat Genet doi: 10.1038/ng1531 – volume: 25 start-page: 677 issue: 12 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0105 article-title: The chemokine system in diverse forms of macrophage activation and polarization publication-title: Trends Immunol doi: 10.1016/j.it.2004.09.015 – volume: 284 start-page: 34839 issue: 50 year: 2009 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0605 article-title: Leukocyte Ig-like receptor B4 (LILRB4) is a potent inhibitor of FcγRI-mediated monocyte activation via dephosphorylation of multiple kinases publication-title: J Biol Chem doi: 10.1074/jbc.M109.035683 – volume: 119 start-page: 99 issue: Suppl. year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0415 article-title: Use of cDNA microarrays to analyze responses to pneumococcal virulence factors publication-title: Indian J Med Res – volume: 100 start-page: 6952 issue: 12 year: 2003 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0035 article-title: A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0732111100 – volume: 177 start-page: 207 issue: 1–2 year: 1994 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0175 article-title: A sensitive ELISA for measuring the adhesion of leukocytic cells to human endothelial cells publication-title: J Immunol Methods doi: 10.1016/0022-1759(94)90158-9 – volume: 57 start-page: 465 issue: 4 year: 2008 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0255 article-title: The antiadipogenic effect of macrophage-conditioned medium depends on ERK1/2 activation publication-title: Metabolism doi: 10.1016/j.metabol.2007.11.005 – volume: 281 start-page: 29641 issue: 40 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0620 article-title: Human macrophage migration inhibitory factor publication-title: J Biol Chem doi: 10.1074/jbc.M601103200 – volume: 277 start-page: 27927 issue: 31 year: 2002 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0555 article-title: Gamma interferon and granulocyte/monocyte colony-stimulating factor prevent endotoxin tolerance in human monocytes by promoting interleukin-1 receptor-associated kinase expression and its association to MyD88 and not by modulating TLR4 expression publication-title: J Biol Chem doi: 10.1074/jbc.M200705200 – volume: 18 start-page: 1589 issue: 10 year: 1998 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0575 article-title: Cholesterol metabolism and efflux in human THP-1 macrophages publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.ATV.18.10.1589 – volume: 287 start-page: C707 issue: 3 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0200 article-title: Growth factors induce monocyte binding to vascular smooth muscle cells: implications for monocyte retention in atherosclerosis publication-title: Am J Physiol Cell Physiol doi: 10.1152/ajpcell.00170.2004 – volume: 363 start-page: 1020 issue: 4 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0580 article-title: Perilipin and adipophilin expression in lipid loaded macrophages publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2007.09.074 – volume: 17 start-page: 150 issue: 2 year: 2010 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0445 article-title: MicroRNAs in atherosclerosis and lipoprotein metabolism publication-title: Curr Opin Endocrinol Diabetes Obes doi: 10.1097/MED.0b013e32833727a1 – volume: 150 start-page: 1 issue: 1–3 year: 2008 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0220 article-title: Newly developed angiotensin II-infused experimental models in vascular biology publication-title: Regul Pept doi: 10.1016/j.regpep.2008.05.002 – volume: 318 start-page: 265 issue: 1 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0330 article-title: Atorvastatin reduces CD68: FABP4, and HBP expression in oxLDL-treated human macrophages publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2004.04.021 – volume: 280 start-page: 21078 issue: 22 year: 2005 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0600 article-title: Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms publication-title: J Biol Chem doi: 10.1074/jbc.M500543200 – volume: 148 start-page: 1 issue: 1 year: 2000 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0190 article-title: A proposed model for the assembly of chylomicrons publication-title: Atherosclerosis doi: 10.1016/S0021-9150(99)00397-4 – volume: 281 start-page: 27526 issue: 37 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0050 article-title: Monocyte differentiation up-regulates the expression of the lysosomal sialidase: Neu1, and triggers its targeting to the plasma membrane via major histocompatibility complex class II-positive compartments publication-title: J Biol Chem doi: 10.1074/jbc.M605633200 – volume: 2011 issue: 5 year: 2011 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0095 article-title: Improved protocol for efficient nonviral transfection of premature THP-1 macrophages publication-title: Cold Spring Harb Protoc doi: 10.1101/pdb.prot5612 – volume: 276 start-page: 45729 issue: 49 year: 2001 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0325 article-title: Oxidized low density lipoprotein exposure alters the transcriptional response of macrophages to inflammatory stimulus publication-title: J Biol Chem doi: 10.1074/jbc.M106114200 – volume: 205 start-page: 585 issue: 3 year: 2008 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0465 article-title: Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder publication-title: J Exp Med doi: 10.1084/jem.20072108 – volume: 344 start-page: 109 issue: 2 year: 2009 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0090 article-title: Efficient non-viral transfection of THP-1 cells publication-title: J Immunol Methods doi: 10.1016/j.jim.2009.03.014 – volume: 37 start-page: 71 issue: 1 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0075 article-title: Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: specific induction of the promoter in human macrophages by oxidized low-density lipoproteins publication-title: Free Radic Biol Med doi: 10.1016/j.freeradbiomed.2004.04.016 – volume: 25 start-page: 8 issue: 1 year: 2001 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0265 article-title: Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation publication-title: Int J Obes Relat Metab Disord doi: 10.1038/sj.ijo.0801520 – volume: 8 start-page: 45 issue: 1 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0360 article-title: Changes of gene expression profiles in macrophages stimulated by angiotensin II—angiotensin II induces MCP-2 through AT1-receptor publication-title: J Renin Angiotensin Aldosterone Syst doi: 10.3317/jraas.2007.007 – volume: 112 start-page: 61 issue: 2 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0245 article-title: Adipose tissue macrophages publication-title: Immunol Lett doi: 10.1016/j.imlet.2007.07.003 – volume: 104 start-page: 99 issue: 1 year: 2001 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0400 article-title: Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach publication-title: Immunology doi: 10.1046/j.1365-2567.2001.01274.x – volume: 100 start-page: 2182 issue: 9 year: 1997 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0495 article-title: Genomic instability in the type II TGF-beta1 receptor gene in atherosclerotic and restenotic vascular cells publication-title: J Clin Invest doi: 10.1172/JCI119754 – volume: 91 start-page: 9 issue: 1 year: 2002 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0205 article-title: Induction of bone-type alkaline phosphatase in human vascular smooth muscle cells: roles of tumor necrosis factor-alpha and oncostatin M derived from macrophages publication-title: Circ Res doi: 10.1161/01.RES.0000026421.61398.F2 – volume: 279 start-page: 29147 issue: 28 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0540 article-title: DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E publication-title: J Biol Chem doi: 10.1074/jbc.M403618200 – volume: 91 start-page: 681 issue: 8 year: 2002 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0285 article-title: Cooperation between secretory phospholipase A2 and TNF-receptor superfamily signaling: implications for the inflammatory response in atherogenesis publication-title: Circ Res doi: 10.1161/01.RES.0000038341.34243.64 – volume: 185 start-page: 6253 issue: 10 year: 2010 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0475 article-title: Endothelin-1-induced macrophage inflammatory protein-1 beta expression in monocytic cells involves hypoxia-inducible factor-1 alpha and AP-1 and is negatively regulated by microRNA-195 publication-title: J Immunol doi: 10.4049/jimmunol.1000660 – volume: 36 start-page: 152 issue: 2 year: 2000 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0215 article-title: Interaction between monocytes and vascular smooth muscle cells enhances matrix metalloproteinase-1 production publication-title: J Cardiovasc Pharmacol doi: 10.1097/00005344-200008000-00003 – volume: 279 start-page: 21924 issue: 21 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0045 article-title: Cryopyrin-induced interleukin 1 beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC publication-title: J Biol Chem doi: 10.1074/jbc.M401178200 – volume: 106 start-page: 505 issue: 3 year: 1989 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0135 article-title: Expression of the apolipoprotein E gene in a human macrophage-like cell line: THP-1 publication-title: J Biochem doi: 10.1093/oxfordjournals.jbchem.a122882 – volume: 283 start-page: 36221 issue: 52 year: 2008 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0480 article-title: Distinct roles of heterogeneous nuclear ribonuclear protein K and microRNA-16 in cyclooxygenase-2 RNA stability induced by S100 b: a ligand of the receptor for advanced glycation end products publication-title: J Biol Chem doi: 10.1074/jbc.M806322200 – volume: 280 start-page: 7845 issue: 9 year: 2005 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0055 article-title: The amyloid-beta peptide suppresses transforming growth factor-beta1-induced matrix metalloproteinase-2 production via Smad7 expression in human monocytic THP-1 cells publication-title: J Biol Chem doi: 10.1074/jbc.M409101200 – volume: 8 start-page: 1 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0420 article-title: Transcriptional profiling of the LPS induced NF-kappaB response in macrophages publication-title: BMC Immunol doi: 10.1186/1471-2172-8-1 – volume: 83 start-page: 270 issue: 3 year: 1998 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0615 article-title: Expression of tissue inhibitor of metalloproteinases-3 in human atheroma and regulation in lesion-associated cells: a potential protective mechanism in plaque stability publication-title: Circ Res doi: 10.1161/01.RES.83.3.270 – volume: 48 start-page: 385 issue: 2 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0370 article-title: Suppression of endothelial or lipoprotein lipase in THP-1 macrophages attenuates proinflammatory cytokine secretion publication-title: J Lipid Res doi: 10.1194/jlr.M600304-JLR200 – volume: 258 start-page: 13425 issue: 22 year: 1983 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0570 article-title: Cellular cholesteryl ester clearance. Relationship to the physical state of cholesteryl ester inclusions publication-title: J Biol Chem doi: 10.1016/S0021-9258(17)43931-7 – volume: 285 start-page: 24404 issue: 32 year: 2010 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0625 article-title: Interleukin-27 induces a STAT1/3- and NF-κB-dependent proinflammatory cytokine profile in human monocytes publication-title: J Biol Chem doi: 10.1074/jbc.M110.112599 – volume: 67 start-page: 1935 issue: 6 year: 2005 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0355 article-title: Retinoids potentiate peroxisome proliferator-activated receptor gamma action in differentiation: gene expression, and lipid metabolic processes in developing myeloid cells publication-title: Mol Pharmacol doi: 10.1124/mol.104.006445 – volume: 299 start-page: E1016 issue: 6 year: 2010 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0110 article-title: Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation publication-title: Am J Physiol Endocrinol Metab doi: 10.1152/ajpendo.00329.2010 – volume: 99 start-page: 1497 issue: 3 year: 2002 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0290 article-title: Cooperation of multiple signaling pathways in CD40-regulated gene expression in B lymphocytes publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.032665099 – volume: 275 start-page: 11181 issue: 15 year: 2000 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0390 article-title: Monitoring cellular responses to Listeria monocytogenes with oligonucleotide arrays publication-title: J Biol Chem doi: 10.1074/jbc.275.15.11181 – volume: 281 start-page: 31142 issue: 41 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0335 article-title: A dominant function of IKK/NF-kappaB signaling in global lipopolysaccharide-induced gene expression publication-title: J Biol Chem doi: 10.1074/jbc.M603417200 – volume: 51 start-page: 1048 issue: 3 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0375 article-title: Expression of immunomodulatory genes in human monocytes induced by voriconazole in the presence of Aspergillus fumigatus publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.01095-06 – volume: 141 start-page: 2656 issue: 8 year: 1988 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0100 article-title: A monoclonal antibody reacting with distinct adhesion molecules defines a transition in the functional state of the receptor CD11 b/CD18 (Mac-1) publication-title: J Immunol doi: 10.4049/jimmunol.141.8.2656 – volume: 41 start-page: 395 issue: 2 year: 1999 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0210 article-title: Cellular adhesion molecules on vascular smooth muscle cells publication-title: Cardiovasc Res doi: 10.1016/S0008-6363(98)00302-2 – volume: 278 start-page: 37275 issue: 39 year: 2003 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0590 article-title: Tumor necrosis factor-α induces functionally active hyaluronan-adhesive CD44 by activating sialidase through p38 mitogen-activated protein kinase in lipopolysaccharide-stimulated human monocytic cells publication-title: J Biol Chem doi: 10.1074/jbc.M302309200 – volume: 339 start-page: 105 issue: 1–2 year: 2011 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0270 article-title: An inflammatory micro-environment promotes human adipocyte apoptosis publication-title: Mol Cell Endocrinol doi: 10.1016/j.mce.2011.04.004 – volume: 93 start-page: 4059 issue: 12 year: 1999 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0530 article-title: DNA methylation publication-title: Blood doi: 10.1182/blood.V93.12.4059 – volume: 72 start-page: 417 issue: 3 year: 2002 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0040 article-title: Macrophages in gene therapy: cellular delivery vehicles and in vivo targets publication-title: J Leukoc Biol doi: 10.1189/jlb.72.3.417 – volume: 282 start-page: 13854 issue: 18 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0520 article-title: Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes publication-title: J Biol Chem doi: 10.1074/jbc.M609446200 – volume: 5 start-page: 396 issue: 5 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0435 article-title: Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs publication-title: Nat Rev Genet doi: 10.1038/nrg1328 – volume: 71 start-page: 2087 issue: 4 year: 2003 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0030 article-title: Pneumolysin-dependent and -independent gene expression identified by cDNA microarray analysis of THP-1 human mononuclear cells stimulated by Streptococcus pneumoniae publication-title: Infect Immun doi: 10.1128/IAI.71.4.2087-2094.2003 – volume: 107 start-page: 501 issue: 4 year: 2010 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0185 article-title: Deficiency of the NR4 A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis publication-title: Circ Res doi: 10.1161/CIRCRESAHA.110.222083 – volume: 92 start-page: 405 issue: 3 year: 2010 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0240 article-title: Osteocalcin and atherosclerosis: a complex relationship publication-title: Diabetes Res Clin Pract doi: 10.1016/j.diabres.2010.08.019 – volume: 5 start-page: e8668 issue: 1 year: 2010 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0020 article-title: The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages publication-title: PLoS ONE doi: 10.1371/journal.pone.0008668 – volume: 990 start-page: 701 year: 2003 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0410 article-title: Comparative DNA microarray analysis of host cell transcriptional responses to infection by Coxiella burnetii or Chlamydia trachomatis publication-title: Ann N Y Acad Sci doi: 10.1111/j.1749-6632.2003.tb07447.x – volume: 105 start-page: 650 issue: 5 year: 2002 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0230 article-title: Monocyte/macrophage regulation of vascular calcification in vitro publication-title: Circulation doi: 10.1161/hc0502.102969 – volume: 103 start-page: 12481 issue: 33 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0455 article-title: NF-kappaB-dependent induction of microRNA miR-146: an inhibitor targeted to signaling proteins of innate immune responses publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0605298103 – volume: 111 start-page: 1439 issue: 11 year: 2005 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0080 article-title: HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo publication-title: Circulation doi: 10.1161/01.CIR.0000158484.18024.1F – volume: 7 start-page: 510 issue: 9 year: 2010 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0505 article-title: Epigenetics and cardiovascular disease publication-title: Nat Rev Cardiol doi: 10.1038/nrcardio.2010.104 – volume: 32 start-page: 902 issue: 6 year: 2008 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0260 article-title: Macrophages regulate tumor necrosis factor-alpha expression in adipocytes through the secretion of matrix metalloproteinase-3 publication-title: Int J Obes (Lond) doi: 10.1038/ijo.2008.7 – volume: 26 start-page: 61 issue: 1 year: 2000 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0525 article-title: Large-scale human promoter mapping using CpG islands publication-title: Nat Genet doi: 10.1038/79189 – volume: 263 start-page: 7007 issue: 15 year: 1988 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0115 article-title: The saturable high affinity association of factor X to ADP-stimulated monocytes defines a novel function of the Mac-1 receptor publication-title: J Biol Chem doi: 10.1016/S0021-9258(18)68596-5 – volume: 279 start-page: 51897 issue: 50 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0085 article-title: PAN1/NALP2/PYPAF2: an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages publication-title: J Biol Chem doi: 10.1074/jbc.M406741200 – volume: 1761 start-page: 793 issue: 7 year: 2006 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0180 article-title: Cytokine-induced monocyte adhesion to endothelial cells involves platelet-activating factor: suppression by conjugated linoleic acid publication-title: Biochim Biophys Acta doi: 10.1016/j.bbalip.2006.05.014 – volume: 102 start-page: 250 issue: 2 year: 2008 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0150 article-title: Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet publication-title: Circ Res doi: 10.1161/CIRCRESAHA.107.156554 – volume: 47 start-page: 2161 issue: 11 year: 2007 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0310 article-title: Platelet and red blood cell phagocytosis kinetics are differentially controlled by phosphatase activity within mononuclear cells publication-title: Transfusion doi: 10.1111/j.1537-2995.2007.01441.x – volume: 150 start-page: 5330 issue: 12 year: 1993 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0275 article-title: T cell-macrophage cognate interaction in the activation of macrophage effector function by Th2 cells publication-title: J Immunol doi: 10.4049/jimmunol.150.12.5330 – volume: 123 start-page: 2145 issue: 19 year: 2011 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0500 article-title: Epigenetic modifications: basic mechanisms and role in cardiovascular disease publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.110.956839 – volume: 46 start-page: 2114 issue: 10 year: 2005 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0585 article-title: Redistribution of macrophage cholesteryl ester hydrolase from cytoplasm to lipid droplets upon lipid loading publication-title: J Lipid Res doi: 10.1194/jlr.M500207-JLR200 – volume: 59 start-page: 555 issue: 4 year: 1996 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0015 article-title: Differences in the state of differentiation of THP-1 cells induced by phorbol ester and 1,25-dihydroxyvitamin D3 publication-title: J Leukoc Biol doi: 10.1002/jlb.59.4.555 – volume: 271 start-page: 8837 issue: 15 year: 1996 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0130 article-title: Interleukin 8 is induced by cholesterol loading of macrophages and expressed by macrophage foam cells in human atheroma publication-title: J Biol Chem doi: 10.1074/jbc.271.15.8837 – volume: 58 start-page: 200 issue: 1 year: 1976 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0565 article-title: Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques publication-title: J Clin Invest doi: 10.1172/JCI108450 – volume: 6 start-page: 639 issue: 7 year: 2004 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0405 article-title: Differential post-transcriptional activation of human phagocytes by different Pseudomonas aeruginosa isolates publication-title: Cell Microbiol doi: 10.1111/j.1462-5822.2004.00388.x – volume: 120 start-page: 135 issue: 1–2 year: 1996 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0145 article-title: Impaired mobilisation of cholesterol from stored cholesteryl esters in human (THP-1) macrophages publication-title: Atherosclerosis doi: 10.1016/0021-9150(95)05695-5 – volume: 47 start-page: 22 issue: 1 year: 1991 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0025 article-title: The human leukemia cell line, THP-1: a multifacetted model for the study of monocyte–macrophage differentiation publication-title: Experientia doi: 10.1007/BF02041244 – volume: 43 start-page: 618 issue: 4 year: 2002 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0560 article-title: Triglyceride depletion in THP-1 cells alters cholesteryl ester physical state and cholesterol efflux publication-title: J Lipid Res doi: 10.1016/S0022-2275(20)31492-9 – volume: 32 start-page: 35 issue: 1 year: 1991 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0140 article-title: THP-1 cells form foam cells in response to coculture with lipoproteins but not platelets publication-title: J Lipid Res doi: 10.1016/S0022-2275(20)42241-2 – volume: 275 start-page: 37324 issue: 48 year: 2000 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0315 article-title: Large scale gene expression analysis of cholesterol-loaded macrophages publication-title: J Biol Chem doi: 10.1074/jbc.M004732200 – volume: 146 start-page: 1541 issue: 5 year: 1991 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0545 article-title: Lipopolysaccharide: tumor necrosis factor-alpha, and IL-1 beta prevent programmed cell death (apoptosis) in human peripheral blood monocytes publication-title: J Immunol doi: 10.4049/jimmunol.146.5.1541 – volume: 162 start-page: 283 year: 2003 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0630 article-title: Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression publication-title: Am J Pathol doi: 10.1016/S0002-9440(10)63819-9 – volume: 7 start-page: 5 issue: 1 year: 2002 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0535 article-title: DNA hypomethylation and methyltransferase expression in atherosclerotic lesions publication-title: Vasc Med doi: 10.1191/1358863x02vm418oa – volume: 186 start-page: 2552 issue: 4 year: 2011 ident: 10.1016/j.atherosclerosis.2011.09.003_bib0470 article-title: Role of microRNA-214-targeting phosphatase and tensin homolog in advanced glycation end product-induced apoptosis delay in monocytes publication-title: J Immunol doi: 10.4049/jimmunol.1001633
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Snippet	Since their establishment thirty years ago, THP-1 cells have become one of most widely used cell lines to investigate the function and regulation of monocytes... Abstract Since their establishment thirty years ago, THP-1 cells have become one of most widely used cell lines to investigate the function and regulation of...
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SubjectTerms	adipocytes Adipocytes - pathology adipose tissue atherogenesis atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood Platelets Blood Platelets - pathology Blood Vessels Blood Vessels - metabolism Blood Vessels - pathology Blood vessels and receptors Cardiology. Vascular system Cardiovascular Cell Communication Cell Line, Tumor diabetes mellitus endothelial cells Endothelial Cells - pathology Epigenesis, Genetic Epigenetics Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Regulation, Neoplastic genetics glucose histones Humans inflammation leukemia Leukemia, Monocytic, Acute Leukemia, Monocytic, Acute - genetics Leukemia, Monocytic, Acute - metabolism Leukemia, Monocytic, Acute - pathology lipopolysaccharides low density lipoprotein Macrophage macrophages Macrophages - metabolism Macrophages - pathology Medical sciences metabolism microRNA MicroRNAs MicroRNAs - metabolism Monocyte monocytes Monocytes - metabolism Monocytes - pathology myocytes Myocytes, Smooth Muscle Myocytes, Smooth Muscle - pathology obesity pathology pathophysiology patients physiology smooth muscle T-lymphocytes T-Lymphocytes - pathology Transcriptome Vascular Diseases Vascular Diseases - genetics Vascular Diseases - metabolism Vascular Diseases - pathology Vertebrates: cardiovascular system
Title	The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature
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