Neural correlates of attention bias to threat in post-traumatic stress disorder

• Published in: Biological psychology Vol. 90; no. 2; pp. 134 - 142
• Main Authors: Fani, Negar, Jovanovic, Tanja, Ely, Timothy D., Bradley, Bekh, Gutman, David, Tone, Erin B., Ressler, Kerry J.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.05.2012; Elsevier
• Subjects: Adult; Adult and adolescent clinical studies; Analysis of Variance; Anxiety disorders. Neuroses; Attention; Attention bias; Behavioral psychophysiology; Bias; Biological and medical sciences; Brain Mapping; Cerebral Cortex - blood supply; Cerebral Cortex - pathology; Facial Expression; Fear - psychology; Female; fMRI; Fundamental and applied biological sciences. Psychology; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Medical sciences; Middle Aged; Neuroimaging; Neuropsychological Tests; Oxygen - blood; Photic Stimulation; Post-traumatic stress disorder; Prefrontal cortex; Psychiatric Status Rating Scales; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Psychopathology. Psychiatry; PTSD; Stress Disorders, Post-Traumatic - pathology; Stress Disorders, Post-Traumatic - physiopathology; Stress Disorders, Post-Traumatic - psychology; Threat; Young Adult; PTSD; Neuroimaging; fMRI; Prefrontal cortex; Attention bias; Threat; Central nervous system; Anxiety disorder; Attention; Posttraumatic stress disorder; Nuclear magnetic resonance imaging; Stress; Encephalon; Functional magnetic resonance imaging; Cognitive bias; Functional imaging

► Behavioral and neuroimaging methods were combined to examine attention bias in a traumatized sample. ► PTSD+ individuals demonstrated increased activation to threat in a cognitive control brain region. ► Threat cue avoidance corresponded with increased activation in an emotion processing region in...