Complete sequences of epidermin and nukacin encoding plasmids from oral-derived Staphylococcus epidermidis and their antibacterial activity

• Published in: PloS one Vol. 17; no. 1; p. e0258283
• Main Authors: Nakazono, Kenta, Le, Mi Nguyen-Tra, Kawada-Matsuo, Miki, Kimheang, Noy, Hisatsune, Junzo, Oogai, Yuichi, Nakata, Masanobu, Nakamura, Norifumi, Sugai, Motoyuki, Komatsuzawa, Hitoshi
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 18.01.2022; Public Library of Science (PLoS)
• Subjects: Activity patterns; Amino Acid Sequence; Amino acids; Anti-Bacterial Agents - pharmacology; Antibacterial activity; Antibiotics; Antimicrobial agents; Antimicrobial peptides; Bacteria; Bacteriocins; Bacteriocins - genetics; Bacteriocins - pharmacology; Bacteriology; Biology and Life Sciences; Catheters; Drug resistance; Flora; Gene sequencing; Genes; Genetic aspects; Genomes; Health aspects; Health sciences; Humans; Identification and classification; Infectious diseases; Maxillofacial surgery; Medicine and Health Sciences; Microbial Sensitivity Tests; Mouth - microbiology; Peptides; Phenols; Plasmids; Plasmids - genetics; Research and Analysis Methods; Staphylococcus; Staphylococcus epidermidis; Staphylococcus epidermidis - drug effects; Staphylococcus epidermidis - genetics; Strains (organisms); Streptococcus infections; University graduates; Japan; United States > US

Staphylococcus epidermidis is a commensal bacterium in humans. To persist in the bacterial flora of the host, some bacteria produce antibacterial factors such as the antimicrobial peptides known as bacteriocins. In this study, we tried to isolate bacteriocin-producing S. epidermidis strains. Among 1...