Diagnostic Accuracy of Antigen 5-Based ELISAs for Human Cystic Echinococcosis

• Published in: PLoS neglected tropical diseases Vol. 10; no. 3; p. e0004585
• Main Authors: Pagnozzi, Daniela, Addis, Maria Filippa, Biosa, Grazia, Roggio, Anna Maria, Tedde, Vittorio, Mariconti, Mara, Tamarozzi, Francesca, Meroni, Valeria, Masu, Gabriella, Masala, Giovanna, Brunetti, Enrico, Uzzau, Sergio
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 29.03.2016; Public Library of Science (PLoS)
• Subjects: Accuracy; Animals; Antigen-antibody reactions; Antigens; Antigens, Helminth - immunology; Antigens, Helminth - metabolism; Biology and Life Sciences; Chemotherapy; Cysts; Diagnosis; Disease; Drug therapy; Echinococcosis; Echinococcosis - diagnosis; Echinococcus granulosus; Echinococcus granulosus - metabolism; Enzyme-Linked Immunosorbent Assay - methods; Experiments; Health care; Hospitals; Humans; Immunologic tests; Laboratories; Livestock; Medicine and Health Sciences; Parasites; Research and Analysis Methods; Sensitivity and Specificity; Serologic Tests - methods; Studies; Tropical diseases; Zoonoses; Taiwan

Clinical diagnosis and follow up of cystic echinococcosis (CE) are based on imaging complemented by serology. Several immunodiagnostic tests are commercially available, but the development of new tools is still needed to overcome the lack of standardization of the target antigen, generally consistin...