The Human Glomerular Podocyte Is a Novel Target for Insulin Action

• Published in: Diabetes (New York, N.Y.) Vol. 54; no. 11; pp. 3095 - 3102
• Main Authors: Coward, Richard J.M., Welsh, Gavin I., Yang, Jing, Tasman, Candida, Lennon, Rachel, Koziell, Ania, Satchell, Simon, Holman, Geoffrey D., Kerjaschki, Dontscho, Tavaré, Jeremy M., Mathieson, Peter W., Saleem, Moin A.
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.11.2005
• Subjects: Actins - metabolism; Adipocytes; Albumin; Animals; Antibodies; Biological and medical sciences; Biological Transport - drug effects; Cell Line; Cells; Cytoskeleton; Diabetes; Diabetes research; Diabetes. Impaired glucose tolerance; Diabetic nephropathy; Dose-Response Relationship, Drug; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Endothelial Cells - metabolism; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Gene Silencing; Glucose; Glucose - metabolism; Glucose Transporter Type 1 - genetics; Glucose Transporter Type 1 - metabolism; Glucose Transporter Type 4 - genetics; Glucose Transporter Type 4 - metabolism; Health aspects; Humans; Insulin; Insulin - pharmacology; Insulin resistance; Medical sciences; Mice; Phosphorylation - drug effects; Podocytes - drug effects; Podocytes - metabolism; Podocytes - ultrastructure; Protein Transport; Proteins; Signal Transduction - drug effects; United Kingdom > UK; Ann Arbor Michigan; United States > US; Endocrinopathy; Human; Podocyte; Pancreatic hormone; Insulin; Diabetes mellitus

The Human Glomerular Podocyte Is a Novel Target for Insulin Action Richard J.M. Coward 1 , Gavin I. Welsh 2 , Jing Yang 3 , Candida Tasman 1 , Rachel Lennon 1 , Ania Koziell 4 , Simon Satchell 1 , Geoffrey D. Holman 3 , Dontscho Kerjaschki 5 , Jeremy M. Tavaré 2 , Peter W. Mathieson 1 and Moin A. Sa...