Implitapide, a Microsomal Triglyceride Transfer Protein Inhibitor, Reduces Progression of Atherosclerosis in Apolipoprotein E Knockout Mice Fed a Western-Type Diet: Involvement of the Inhibition of Postprandial Triglyceride Elevation - Ueshima, Koji; Akihisa-Umeno, Hitomi; Nagayoshi, Akira; Takakura, Shoji; Matsuo, Masahiko; Mutoh, Seitaro (Biological & Pharmaceutical Bulletin, 2005)
Keywords: Animals; Aorta, Thoracic - drug effects; Aorta, Thoracic - metabolism; Apolipoproteins E - deficiency; Apolipoproteins E - genetics; Arteriosclerosis - blood; Arteriosclerosis - prevention & control; atherosclerosis; Carrier Proteins - antagonists & inhibitors; Carrier Proteins - blood; Diet, Atherogenic; Dietary Fats - administration & dosage; implitapide; Indoles - pharmacology; Indoles - therapeutic use; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; microsomal triglyceride transfer protein; Postprandial Period - drug effects; Postprandial Period - physiology; Pyridines - pharmacology; Pyridines - therapeutic use; Triglycerides - antagonists & inhibitors; Triglycerides - blood