Role of miR-122 and lipid metabolism in HCV infection

• Published in: Journal of gastroenterology Vol. 48; no. 2; pp. 169 - 176
• Main Authors: Fukuhara, Takasuke, Matsuura, Yoshiharu
• Format: Journal Article
• Language: English
• Published: Japan Springer Japan 01.02.2013; Springer; Springer Nature B.V
• Subjects: Abdominal Surgery; Animals; Colorectal Surgery; Disease susceptibility; Gastroenterology; HCV; Health aspects; Hepacivirus - physiology; Hepatitis C - metabolism; Hepatitis C virus; Hepatology; Humans; Infection; Lipid metabolism; Lipid Metabolism - physiology; Liver; Low density lipoproteins; Medicine; Medicine & Public Health; MicroRNA; MicroRNAs - physiology; miR-122; Physiological aspects; Review; Surgical Oncology; T cells; Viral Tropism - physiology; Virus Assembly - physiology; miR-122; HCV; Lipid metabolism

Hepatitis C virus (HCV) exhibits a narrow host range and a specific tissue tropism. Mice expressing major entry receptors for HCV permit viral entry, and therefore the species tropism of HCV infection is considered to be reliant on the expression of the entry receptors. However, HCV receptor candida...