Clinical Validation of Deep Learning for Image Restoration of Ultra-Low-Count [ 18 F]FDG PET for Dementia Diagnostics

• Published in: Journal of Nuclear Medicine p. jnumed.124.269234
• Main Authors: Schiller, Florian, Brumberg, Joachim, Frings, Lars, Deschamps, Joran, Schmied, Christopher, Jug, Florian, Mix, Michael, Meyer, Philipp T.
• Format: Journal Article
• Language: English
• Published: United States 14.08.2025
• Subjects: scan duration; deep learning; [18F]FDG PET; dementia; radiation dose

Deep learning (DL) represents a promising technique for image restoration. We explored its ability to restore ultra-low-count [ F]FDG PET studies of the brain in subjects with dementia and in healthy subjects to allow for reduced scan durations or administered activities without compromising diagnos...