Silymarin suppresses basal and stimulus-induced activation, exhaustion, differentiation, and inflammatory markers in primary human immune cells - Lovelace, Erica S.; Maurice, Nicholas J.; Miller, Hannah W.; Slichter, Chloe K.; Harrington, Robert; Magaret, Amalia; Prlic, Martin; De Rosa, Stephen; Polyak, Stephen J. (PloS one, 2017)
Keywords: Acquired immune deficiency syndrome; AIDS; Biology and Life Sciences; Biomarkers - metabolism; CD4 antigen; CD4-Positive T-Lymphocytes - drug effects; CD4-Positive T-Lymphocytes - metabolism; CD8 antigen; CD8-Positive T-Lymphocytes - drug effects; CD8-Positive T-Lymphocytes - metabolism; Cell activation; Cell lines; Cells, Cultured; Chronic infection; Cytokines; Exhaustion; Flow Cytometry; Hepatocytes; HIV; HIV infections; HIV Infections - immunology; Human immunodeficiency virus; Humans; Immune system; Immunological memory; Immunoregulation; Inflammation; Inflammation - metabolism; Leukocytes, Mononuclear - drug effects; Leukocytes, Mononuclear - metabolism; Liver; Lymphocyte Activation - drug effects; Lymphocytes; Lymphocytes T; Markers; Medicine and Health Sciences; Metabolism; Milk thistle; Monocytes; Mucosa; Mucosal-Associated Invariant T Cells - drug effects; Mucosal-Associated Invariant T Cells - metabolism; Pathogen-Associated Molecular Pattern Molecules - metabolism; Receptors, Antigen, T-Cell - metabolism; Research and Analysis Methods; Silybum marianum; Silymarin; Silymarin - pharmacology; Stem cells; T cell receptors; T cells; T-cell receptor; T-Lymphocyte Subsets - drug effects; T-Lymphocyte Subsets - metabolism; United States--US