Maternal serum persistent organic pollutants in the Finnish Prenatal Study of Autism: A pilot study
Recent research emphasizes the contribution of environmental as well as genetic factors to the etiology of autism but studies testing associations between chemical exposures and autism have been limited. Prenatal exposure to persistent organic pollutants (POPs) has previously been associated with de...
Saved in:
| Published in | Neurotoxicology and teratology Vol. 38; pp. 1 - 5 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.07.2013
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Recent research emphasizes the contribution of environmental as well as genetic factors to the etiology of autism but studies testing associations between chemical exposures and autism have been limited. Prenatal exposure to persistent organic pollutants (POPs) has previously been associated with decrements in cognitive and developmental performance. We conducted a pilot study in the Finnish Prenatal Study of Autism (FiPS-A). Seventy-five cases with autism and 75 controls matched on sex, birth year, urbanization and maternal age were sampled from first-born children in the Finnish Maternity Cohort, which includes over 1million births. The study sample included births occurring from 1991 to 2000. Subjects were followed up for autism through 2007. DDT, DDE, PCB-118, PCB-138, PCB-153, PCB-156, PCB-170, PCB-180, hexachlorobenzene, and BDE-47 were measured in archived maternal serum samples taken during pregnancy using gas chromatography–high resolution mass spectrometry. Correlations between pollutant measures were assessed and mechanistically-related weighting schemes for summarizing PCB levels were compared. Case and control differences were assessed using graphical and statistical methods. All analytes, with the exception of DDT and BDE-47, were detected above the limit of quantification in all samples. The correlation between levels of individual PCB congeners and weighted summary measures was high (0.71–1.00). Paired t-tests revealed no significant differences between cases and controls for log-transformed mean values of any analyte; however, in an adjusted model the odds ratios for autism were 1.91 (p=0.29) and 1.79 (p=0.36) respectively, for subjects with total PCBs and DDE above the 90th percentile of control values. Levels of prenatal PCB exposure in FIPS-A were similar to the levels which previously correlated with poorer neurodevelopmental measures in other populations. Further study in a larger sample will be required to fully determine whether exposure to high POP levels is associated with autism diagnosis in the population.
•Studies on associations between chemical exposures and autism have been limited.•We conducted a pilot case–control study in the Finnish Prenatal Study of Autism.•Persistent organic pollutants were measured in prenatal maternal serum samples.•6 PCB congeners and DDE were detected in all samples.•Non-statistically significant positive associations with autism were observed. |
|---|---|
| AbstractList | Recent research emphasizes the contribution of environmental as well as genetic factors to the etiology of autism but studies testing associations between chemical exposures and autism have been limited. Prenatal exposure to persistent organic pollutants (POPs) has previously been associated with decrements in cognitive and developmental performance. We conducted a pilot study in the Finnish Prenatal Study of Autism (FiPS-A). Seventy-five cases with autism and 75 controls matched on sex, birth year, urbanization and maternal age were sampled from first-born children in the Finnish Maternity Cohort, which includes over 1million births. The study sample included births occurring from 1991 to 2000. Subjects were followed up for autism through 2007. DDT, DDE, PCB-118, PCB-138, PCB-153, PCB-156, PCB-170, PCB-180, hexachlorobenzene, and BDE-47 were measured in archived maternal serum samples taken during pregnancy using gas chromatography–high resolution mass spectrometry. Correlations between pollutant measures were assessed and mechanistically-related weighting schemes for summarizing PCB levels were compared. Case and control differences were assessed using graphical and statistical methods. All analytes, with the exception of DDT and BDE-47, were detected above the limit of quantification in all samples. The correlation between levels of individual PCB congeners and weighted summary measures was high (0.71–1.00). Paired t-tests revealed no significant differences between cases and controls for log-transformed mean values of any analyte; however, in an adjusted model the odds ratios for autism were 1.91 (p=0.29) and 1.79 (p=0.36) respectively, for subjects with total PCBs and DDE above the 90th percentile of control values. Levels of prenatal PCB exposure in FIPS-A were similar to the levels which previously correlated with poorer neurodevelopmental measures in other populations. Further study in a larger sample will be required to fully determine whether exposure to high POP levels is associated with autism diagnosis in the population.
•Studies on associations between chemical exposures and autism have been limited.•We conducted a pilot case–control study in the Finnish Prenatal Study of Autism.•Persistent organic pollutants were measured in prenatal maternal serum samples.•6 PCB congeners and DDE were detected in all samples.•Non-statistically significant positive associations with autism were observed. Recent research emphasizes the contribution of environmental as well as genetic factors to the etiology of autism but studies testing associations between chemical exposures and autism have been limited. Prenatal exposure to persistent organic pollutants (POPs) has previously been associated with decrements in cognitive and developmental performance. We conducted a pilot study in the Finnish Prenatal Study of Autism (FiPS-A). Seventy-five cases with autism and 75 controls matched on sex, birth year, urbanization and maternal age were sampled from first-born children in the Finnish Maternity Cohort, which includes over 1 million births. The study sample included births occurring from 1991 to 2000. Subjects were followed up for autism through 2007. DDT, DDE, PCB-118, PCB-138, PCB-153, PCB-156, PCB-170, PCB-180, hexachlorobenzene, and BDE-47 were measured in archived maternal serum samples taken during pregnancy using gas chromatography-high resolution mass spectrometry. Correlations between pollutant measures were assessed and mechanistically-related weighting schemes for summarizing PCB levels were compared. Case and control differences were assessed using graphical and statistical methods. All analytes, with the exception of DDT and BDE-47, were detected above the limit of quantification in all samples. The correlation between levels of individual PCB congeners and weighted summary measures was high (0.71-1.00). Paired t-tests revealed no significant differences between cases and controls for log-transformed mean values of any analyte; however, in an adjusted model the odds ratio for autism was 1.91 (p=0.29) and 1.79 (p= 0.36) respectively, for subjects with total PCBs and DDE above the 90 th percentile of control values. Levels of prenatal PCB exposure in FIPS-A were similar to levels previously correlated with poorer neurodevelopmental measures in other populations. Further study in a larger sample will be required to fully determine whether exposure to high POP levels are associated with autism diagnosis in the population. Recent research emphasizes the contribution of environmental as well as genetic factors to the etiology of autism but studies testing associations between chemical exposures and autism have been limited. Prenatal exposure to persistent organic pollutants (POPs) has previously been associated with decrements in cognitive and developmental performance. We conducted a pilot study in the Finnish Prenatal Study of Autism (FiPS-A). Seventy-five cases with autism and 75 controls matched on sex, birth year, urbanization and maternal age were sampled from first-born children in the Finnish Maternity Cohort, which includes over 1million births. The study sample included births occurring from 1991 to 2000. Subjects were followed up for autism through 2007. DDT, DDE, PCB-118, PCB-138, PCB-153, PCB-156, PCB-170, PCB-180, hexachlorobenzene, and BDE-47 were measured in archived maternal serum samples taken during pregnancy using gas chromatography-high resolution mass spectrometry. Correlations between pollutant measures were assessed and mechanistically-related weighting schemes for summarizing PCB levels were compared. Case and control differences were assessed using graphical and statistical methods. All analytes, with the exception of DDT and BDE-47, were detected above the limit of quantification in all samples. The correlation between levels of individual PCB congeners and weighted summary measures was high (0.71-1.00). Paired t-tests revealed no significant differences between cases and controls for log-transformed mean values of any analyte; however, in an adjusted model the odds ratios for autism were 1.91 (p=0.29) and 1.79 (p=0.36) respectively, for subjects with total PCBs and DDE above the 90th percentile of control values. Levels of prenatal PCB exposure in FIPS-A were similar to the levels which previously correlated with poorer neurodevelopmental measures in other populations. Further study in a larger sample will be required to fully determine whether exposure to high POP levels is associated with autism diagnosis in the population. Abstract Recent research emphasizes the contribution of environmental as well as genetic factors to the etiology of autism but studies testing associations between chemical exposures and autism have been limited. Prenatal exposure to persistent organic pollutants (POPs) has previously been associated with decrements in cognitive and developmental performance. We conducted a pilot study in the Finnish Prenatal Study of Autism (FiPS-A). Seventy-five cases with autism and 75 controls matched on sex, birth year, urbanization and maternal age were sampled from first-born children in the Finnish Maternity Cohort, which includes over 1 million births. The study sample included births occurring from 1991 to 2000. Subjects were followed up for autism through 2007. DDT, DDE, PCB-118, PCB-138, PCB-153, PCB-156, PCB-170, PCB-180, hexachlorobenzene, and BDE-47 were measured in archived maternal serum samples taken during pregnancy using gas chromatography–high resolution mass spectrometry. Correlations between pollutant measures were assessed and mechanistically-related weighting schemes for summarizing PCB levels were compared. Case and control differences were assessed using graphical and statistical methods. All analytes, with the exception of DDT and BDE-47, were detected above the limit of quantification in all samples. The correlation between levels of individual PCB congeners and weighted summary measures was high (0.71–1.00). Paired t-tests revealed no significant differences between cases and controls for log-transformed mean values of any analyte; however, in an adjusted model the odds ratios for autism were 1.91 (p = 0.29) and 1.79 (p = 0.36) respectively, for subjects with total PCBs and DDE above the 90th percentile of control values. Levels of prenatal PCB exposure in FIPS-A were similar to the levels which previously correlated with poorer neurodevelopmental measures in other populations. Further study in a larger sample will be required to fully determine whether exposure to high POP levels is associated with autism diagnosis in the population. Recent research emphasizes the contribution of environmental as well as genetic factors to the etiology of autism but studies testing associations between chemical exposures and autism have been limited. Prenatal exposure to persistent organic pollutants (POPs) has previously been associated with decrements in cognitive and developmental performance. We conducted a pilot study in the Finnish Prenatal Study of Autism (FiPS-A). Seventy-five cases with autism and 75 controls matched on sex, birth year, urbanization and maternal age were sampled from first-born children in the Finnish Maternity Cohort, which includes over 1million births. The study sample included births occurring from 1991 to 2000. Subjects were followed up for autism through 2007. DDT, DDE, PCB-118, PCB-138, PCB-153, PCB-156, PCB-170, PCB-180, hexachlorobenzene, and BDE-47 were measured in archived maternal serum samples taken during pregnancy using gas chromatography-high resolution mass spectrometry. Correlations between pollutant measures were assessed and mechanistically-related weighting schemes for summarizing PCB levels were compared. Case and control differences were assessed using graphical and statistical methods. All analytes, with the exception of DDT and BDE-47, were detected above the limit of quantification in all samples. The correlation between levels of individual PCB congeners and weighted summary measures was high (0.71-1.00). Paired t-tests revealed no significant differences between cases and controls for log-transformed mean values of any analyte; however, in an adjusted model the odds ratios for autism were 1.91 (p=0.29) and 1.79 (p=0.36) respectively, for subjects with total PCBs and DDE above the 90th percentile of control values. Levels of prenatal PCB exposure in FIPS-A were similar to the levels which previously correlated with poorer neurodevelopmental measures in other populations. Further study in a larger sample will be required to fully determine whether exposure to high POP levels is associated with autism diagnosis in the population.Recent research emphasizes the contribution of environmental as well as genetic factors to the etiology of autism but studies testing associations between chemical exposures and autism have been limited. Prenatal exposure to persistent organic pollutants (POPs) has previously been associated with decrements in cognitive and developmental performance. We conducted a pilot study in the Finnish Prenatal Study of Autism (FiPS-A). Seventy-five cases with autism and 75 controls matched on sex, birth year, urbanization and maternal age were sampled from first-born children in the Finnish Maternity Cohort, which includes over 1million births. The study sample included births occurring from 1991 to 2000. Subjects were followed up for autism through 2007. DDT, DDE, PCB-118, PCB-138, PCB-153, PCB-156, PCB-170, PCB-180, hexachlorobenzene, and BDE-47 were measured in archived maternal serum samples taken during pregnancy using gas chromatography-high resolution mass spectrometry. Correlations between pollutant measures were assessed and mechanistically-related weighting schemes for summarizing PCB levels were compared. Case and control differences were assessed using graphical and statistical methods. All analytes, with the exception of DDT and BDE-47, were detected above the limit of quantification in all samples. The correlation between levels of individual PCB congeners and weighted summary measures was high (0.71-1.00). Paired t-tests revealed no significant differences between cases and controls for log-transformed mean values of any analyte; however, in an adjusted model the odds ratios for autism were 1.91 (p=0.29) and 1.79 (p=0.36) respectively, for subjects with total PCBs and DDE above the 90th percentile of control values. Levels of prenatal PCB exposure in FIPS-A were similar to the levels which previously correlated with poorer neurodevelopmental measures in other populations. Further study in a larger sample will be required to fully determine whether exposure to high POP levels is associated with autism diagnosis in the population. |
| Author | McKeague, Ian W. Brown, Alan S. Rantakokko, Panu V. Sourander, Andre Kiviranta, Hannu A. Cheslack-Postava, Keely Hinkka-Yli-Salomäki, Susanna Surcel, Heljä-Marja |
| AuthorAffiliation | d National Institute for Health and Welfare, Oulu, Finland e Department of Biostatistics, Columbia University Mailman School of Public Health, New York, NY, United States b National Institute for Health and Welfare (THL) Chemical Exposure Unit, Kuopio, Finland f University Hospital of Turku, Turku, Finland c Department of Child Psychiatry, University of Turku, Turku, Finland a Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, United States g Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY, United States |
| AuthorAffiliation_xml | – name: d National Institute for Health and Welfare, Oulu, Finland – name: a Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, United States – name: f University Hospital of Turku, Turku, Finland – name: e Department of Biostatistics, Columbia University Mailman School of Public Health, New York, NY, United States – name: c Department of Child Psychiatry, University of Turku, Turku, Finland – name: b National Institute for Health and Welfare (THL) Chemical Exposure Unit, Kuopio, Finland – name: g Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY, United States |
| Author_xml | – sequence: 1 givenname: Keely surname: Cheslack-Postava fullname: Cheslack-Postava, Keely email: kc2497@columbia.edu organization: Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, United States – sequence: 2 givenname: Panu V. surname: Rantakokko fullname: Rantakokko, Panu V. organization: National Institute for Health and Welfare (THL), Chemical Exposure Unit, Kuopio, Finland – sequence: 3 givenname: Susanna surname: Hinkka-Yli-Salomäki fullname: Hinkka-Yli-Salomäki, Susanna organization: Department of Child Psychiatry, University of Turku, Turku, Finland – sequence: 4 givenname: Heljä-Marja surname: Surcel fullname: Surcel, Heljä-Marja organization: National Institute for Health and Welfare, Oulu, Finland – sequence: 5 givenname: Ian W. surname: McKeague fullname: McKeague, Ian W. organization: Department of Biostatistics, Columbia University Mailman School of Public Health, New York, NY, United States – sequence: 6 givenname: Hannu A. surname: Kiviranta fullname: Kiviranta, Hannu A. organization: National Institute for Health and Welfare (THL), Chemical Exposure Unit, Kuopio, Finland – sequence: 7 givenname: Andre surname: Sourander fullname: Sourander, Andre organization: Department of Child Psychiatry, University of Turku, Turku, Finland – sequence: 8 givenname: Alan S. surname: Brown fullname: Brown, Alan S. organization: Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, United States |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23591055$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNklFrFDEUhYNU7Lb6A3yRPPqy681kZjJRKCylVaGiUH0O2cydbtZssiaZwv57M2wtWrD6lId7vpN7OeeEHPngkZCXDBYMWPtms_A5LypgfAH1AoA9ITPWiWouBe-OyAw6Wc2Bt9UxOUlpAwCiZfCMHFe8kQyaZkbMJ50xeu1owjhu6Q5jsimjzzTEG-2tobvg3Ji1z4laT_Ma6aX13qY1_RLR61zY6zz2exoGuhyzTdu3dEl31oVM0zR4Tp4O2iV8cfeekm-XF1_PP8yvPr__eL68mpu2afJ8xXveCaxYb5CDQMFrbAfZ6BYNQ96xphwqRFXXKyaBG6g72fRD33EjBtEN_JScHXx342qLxcXnqJ3aRbvVca-CturPibdrdRNuFReMMwbF4PWdQQw_RkxZbW0y6Jz2GMakWFsJ2bYg_0NaA3ApRVsV6avf17rf51cIRcAOAhNDShGHewkDNQWtNqoEraagFdSqBF0Y8YAxNutsw3SZdY-S7w4klihuLUaVjEVvsLcRTVZ9sI_SZw9o42xpiXbfcY9pE8apTOV-lSoF6nqq4NRAxgvNhCgG8u8G__j8J7iU604 |
| CitedBy_id | crossref_primary_10_1007_s11356_019_05666_1 crossref_primary_10_1016_j_envres_2024_118912 crossref_primary_10_1515_reveh_2022_0092 crossref_primary_10_1146_annurev_publhealth_031816_044318 crossref_primary_10_1590_1984_0462_2023_41_2021360 crossref_primary_10_3390_ijerph121114780 crossref_primary_10_1289_EHP277 crossref_primary_10_1016_j_cppeds_2014_06_001 crossref_primary_10_1016_j_jsbmb_2015_08_021 crossref_primary_10_1016_j_cbi_2022_110226 crossref_primary_10_1016_j_chroma_2013_07_064 crossref_primary_10_1002_chem_201903904 crossref_primary_10_1021_acs_est_9b00535 crossref_primary_10_1289_ehp_1307261 crossref_primary_10_3390_jcm8020217 crossref_primary_10_3390_ijerph16081438 crossref_primary_10_1007_s12291_018_0791_5 crossref_primary_10_1111_aji_12505 crossref_primary_10_1016_j_neuro_2024_06_016 crossref_primary_10_3389_fncel_2022_985943 crossref_primary_10_1016_j_neuro_2013_12_003 crossref_primary_10_1093_toxsci_kfy277 crossref_primary_10_1016_j_envpol_2022_120381 crossref_primary_10_1371_journal_pone_0129906 crossref_primary_10_1016_j_chemosphere_2022_137459 crossref_primary_10_3390_children5120157 crossref_primary_10_1007_s10803_021_05063_z crossref_primary_10_1016_j_yhbeh_2017_10_003 crossref_primary_10_1016_j_envpol_2019_07_066 crossref_primary_10_1016_j_etap_2025_104679 crossref_primary_10_1016_j_envres_2023_115978 crossref_primary_10_1177_1087054720940402 crossref_primary_10_3109_08039488_2015_1011692 crossref_primary_10_1093_ije_dyt282 crossref_primary_10_1097_EDE_0000000000000983 crossref_primary_10_1016_j_gloepi_2020_100040 crossref_primary_10_1007_s00204_016_1849_x crossref_primary_10_1016_j_rasd_2020_101587 crossref_primary_10_1111_jcpp_12501 crossref_primary_10_1016_j_envint_2018_10_028 crossref_primary_10_1093_aje_kwab065 crossref_primary_10_1038_tp_2014_4 crossref_primary_10_1007_s40572_015_0064_x crossref_primary_10_1289_EHP1830 crossref_primary_10_2174_0109298673252471231121045529 crossref_primary_10_17340_jkna_2018_3_1 crossref_primary_10_1016_j_scitotenv_2020_140599 crossref_primary_10_1176_appi_ajp_2018_17101129 crossref_primary_10_1177_13623613211039950 crossref_primary_10_1186_s13229_021_00429_7 crossref_primary_10_1530_EC_18_0029 crossref_primary_10_3345_cep_2020_00864 crossref_primary_10_1016_j_chemosphere_2022_135569 crossref_primary_10_1007_s00204_018_2307_8 crossref_primary_10_3390_toxics8030070 crossref_primary_10_3345_cep_2023_00941 crossref_primary_10_1002_aur_1938 crossref_primary_10_21020_husbfd_420631 crossref_primary_10_1289_EHP5621 crossref_primary_10_1007_s11356_019_06723_5 crossref_primary_10_1016_j_neuro_2016_10_017 crossref_primary_10_1007_s40474_013_0002_2 crossref_primary_10_1016_j_envres_2020_109709 crossref_primary_10_3389_fnins_2016_00174 crossref_primary_10_3390_ijerph16030457 crossref_primary_10_3390_ijms21031013 crossref_primary_10_1007_s12640_015_9572_6 crossref_primary_10_1016_j_neuro_2023_05_010 crossref_primary_10_2903_j_efsa_2024_8497 crossref_primary_10_1016_j_envpol_2023_122439 crossref_primary_10_1038_s41598_024_82908_4 crossref_primary_10_1016_j_envres_2018_12_061 crossref_primary_10_1016_j_lfs_2015_11_006 |
| Cites_doi | 10.1007/s10803-010-1132-6 10.1093/aje/kwi158 10.1289/ehp.1002727 10.1016/S0022-3476(99)70369-0 10.1111/j.1651-2227.2010.01835.x 10.1289/ehp.5463 10.1289/ehp.10168 10.1016/j.bbr.2008.12.016 10.2307/1130097 10.1016/j.chemosphere.2005.01.064 10.1289/ehp.9566 10.1097/EDE.0b013e3181e65d76 10.1093/toxsci/kfl055 10.1016/j.neuro.2009.01.011 10.1016/S0140-6736(06)69665-7 10.1016/S0892-0362(99)00056-2 10.1038/jes.2011.25 10.1080/00039896.1994.9934409 10.1289/ehp.10553 10.1056/NEJM199609123351104 10.1016/j.neuro.2006.12.009 10.1016/j.chroma.2008.12.013 10.1016/j.yrtph.2009.12.008 10.1038/sj.mp.4001162 10.1067/S0022-3476(03)00577-8 10.1016/S0022-3476(86)80397-3 10.1016/j.placenta.2004.10.001 10.1016/j.ijdevneu.2004.11.001 10.1001/archgenpsychiatry.2011.76 10.1038/sj.jea.7500120 10.1289/ehp.9120 10.1289/ehp.1002835 10.1186/1476-069X-9-51 10.1542/peds.2005-3117 10.1289/ehp.11058 10.1016/j.yrtph.2007.03.005 10.1016/S0378-4274(98)00334-8 |
| ContentType | Journal Article |
| Copyright | 2013 Elsevier Inc. Elsevier Inc. Copyright © 2013 Elsevier Inc. All rights reserved. 2013 Elsevier Inc. All rights reserved. 2013 |
| Copyright_xml | – notice: 2013 Elsevier Inc. – notice: Elsevier Inc. – notice: Copyright © 2013 Elsevier Inc. All rights reserved. – notice: 2013 Elsevier Inc. All rights reserved. 2013 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 7TK 7TV 7U7 C1K 5PM |
| DOI | 10.1016/j.ntt.2013.04.001 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic Neurosciences Abstracts Pollution Abstracts Toxicology Abstracts Environmental Sciences and Pollution Management PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic Pollution Abstracts Toxicology Abstracts Neurosciences Abstracts Environmental Sciences and Pollution Management |
| DatabaseTitleList | MEDLINE Pollution Abstracts MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Public Health |
| EISSN | 1872-9738 |
| EndPage | 5 |
| ExternalDocumentID | PMC3713110 23591055 10_1016_j_ntt_2013_04_001 S0892036213001177 1_s2_0_S0892036213001177 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: NIMH NIH HHS grantid: 5K02-MH65422 – fundername: NIMH NIH HHS grantid: K02 MH065422 – fundername: NIEHS NIH HHS grantid: R01 ES019004 – fundername: NIMH NIH HHS grantid: T32 MH013043 – fundername: National Institute of Mental Health : NIMH grantid: T32 MH013043 || MH – fundername: National Institute of Environmental Health Sciences : NIEHS grantid: R01 ES019004 || ES – fundername: National Institute of Mental Health : NIMH grantid: K02 MH065422 || MH |
| GroupedDBID | --- --K --M .1- .FO .GJ .~1 0R~ 123 1B1 1P~ 1RT 1~. 1~5 29N 4.4 457 4G. 53G 5RE 5VS 7-5 71M 8P~ 9JM AAEDT AAEDW AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AATTM AAXKI AAXLA AAXUO AAYWO ABCQJ ABFRF ABFYP ABIVO ABJNI ABLST ABMAC ABWVN ABXDB ABZDS ACDAQ ACGFO ACGFS ACIUM ACRLP ACRPL ACVFH ADBBV ADCNI ADEZE ADMUD ADNMO AEBSH AEFWE AEIPS AEKER AENEX AEUPX AEVXI AFJKZ AFPUW AFRHN AFTJW AFXIZ AGCQF AGHFR AGQPQ AGUBO AGWIK AGYEJ AHEUO AHHHB AIEXJ AIGII AIIUN AIKHN AITUG AJUYK AKBMS AKIFW AKRWK AKYEP ALCLG ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU APXCP ASPBG AVWKF AXJTR AZFZN BKOJK BLECG BLXMC CS3 DU5 EBS EFJIC EFKBS EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HMQ HMT HVGLF HZ~ IHE J1W KCYFY KOM M2V M34 M41 MO0 MOBAO N9A O-L O9- OAUVE OGGZJ OZT P-8 P-9 P2P PC. Q38 R2- ROL RPZ SCC SDF SDG SDP SES SEW SNS SPCBC SPT SSJ SSN SSP SSZ T5K UNMZH WUQ XPP Z5R ZGI ~G- AACTN AFCTW AFKWA AJOXV AMFUW RIG AADPK AAIAV AATCM ABYKQ AJBFU EFLBG AAYXX AGRNS BNPGV CITATION SSH CGR CUY CVF ECM EIF NPM 7X8 7TK 7TV 7U7 C1K 5PM |
| ID | FETCH-LOGICAL-c655t-b3d387e21dce307e734e6f95a6ec1e381501377244b1903c04895dfd83c7f78f3 |
| IEDL.DBID | .~1 |
| ISSN | 0892-0362 1872-9738 |
| IngestDate | Thu Aug 21 14:27:23 EDT 2025 Thu Jul 10 17:48:20 EDT 2025 Sun Aug 24 04:10:22 EDT 2025 Mon Jul 21 05:59:37 EDT 2025 Thu Apr 24 22:58:50 EDT 2025 Tue Jul 01 03:33:38 EDT 2025 Fri Feb 23 02:25:19 EST 2024 Sun Feb 23 10:20:01 EST 2025 Tue Aug 26 17:48:03 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | Prenatal Autism PCBs DDE Persistent organic pollutants |
| Language | English |
| License | Copyright © 2013 Elsevier Inc. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c655t-b3d387e21dce307e734e6f95a6ec1e381501377244b1903c04895dfd83c7f78f3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/3713110 |
| PMID | 23591055 |
| PQID | 1400399762 |
| PQPubID | 23479 |
| PageCount | 5 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_3713110 proquest_miscellaneous_1627966090 proquest_miscellaneous_1400399762 pubmed_primary_23591055 crossref_primary_10_1016_j_ntt_2013_04_001 crossref_citationtrail_10_1016_j_ntt_2013_04_001 elsevier_sciencedirect_doi_10_1016_j_ntt_2013_04_001 elsevier_clinicalkeyesjournals_1_s2_0_S0892036213001177 elsevier_clinicalkey_doi_10_1016_j_ntt_2013_04_001 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2013-07-01 |
| PublicationDateYYYYMMDD | 2013-07-01 |
| PublicationDate_xml | – month: 07 year: 2013 text: 2013-07-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Neurotoxicology and teratology |
| PublicationTitleAlternate | Neurotoxicol Teratol |
| PublicationYear | 2013 |
| Publisher | Elsevier Inc |
| Publisher_xml | – name: Elsevier Inc |
| References | Eskenazi, Marks, Bradman, Fenster, Johnson, Barr (bb0020) 2006; 118 Patterson (bb0115) 2009; 204 Arndt, Stodgell, Rodier (bb0005) 2005; 23 Grandjean, Landrigan (bb0035) 2006; 368 Longnecker, Wolff, Gladen, Brock, Grandjean, Jacobson (bb0100) 2003; 111 Lampi, Sourander, Gissler, Niemela, Rehnstrom, Pulkkinen (bb0090) 2010; 99 Torres-Sanchez, Rothenberg, Schnaas, Cebrian, Osorio, Del Carmen (bb0160) 2007; 115 Park, Hertz-Picciotto, Sovcikova, Kocan, Drobna, Trnovec (bb0105) 2010; 9 Simon, Britt, James (bb0145) 2007; 48 Stewart, Lonky, Reihman, Pagano, Gump, Darvill (bb0155) 2008; 116 Fenster, Eskenazi, Anderson, Bradman, Hubbard, Barr (bb0025) 2007; 28 Volk, Hertz-Picciotto, Delwiche, Lurmann, McConnell (bb0170) 2011; 119 Windham, Zhang, Gunier, Croen, Grether (bb0175) 2006; 114 Yang, Salmon, Marty (bb0190) 2010; 56 Kalkbrenner, Daniels, Chen, Poole, Emch, Morrissey (bb0070) 2010; 21 Bahena-Medina, Torres-Sanchez, Schnaas, Cebrian, Chavez, Osorio-Valencia (bb0010) 2011; 21 Lampi, Banerjee, Gissler, Hinkka-Yli-Salomaki, Huttunen, Kulmala (bb0085) 2011; 41 Gray, Klebanoff, Brock, Zhou, Darden, Needham (bb0040) 2005; 162 Korrick, Altshul, Tolbert, Burse, Needham, Monson (bb0080) 2000; 10 Winneke, Bucholski, Heinzow, Kramer, Schmidt, Walkowiak (bb0180) 1998; 102–103 Fombonne (bb0030) 2002 Roberts, English, Grether, Windham, Somberg, Wolff (bb0125) 2007; 115 Jacobson, Jacobson (bb0055) 1996; 335 Rogan, Gladen, McKinney, Carreras, Hardy, Thullen (bb0130) 1986; 109 Stewart, Reihman, Lonky, Darvill, Pagano (bb0150) 2000; 22 Greenland, Poole (bb0045) 1994; 49 Van den Berg, Birnbaum, Denison, De, Farland, Feeley (bb0165) 2006; 93 Jacobson, Fein, Jacobson, Schwartz, Dowler (bb0065) 1985; 56 Darvill, Lonky, Reihman, Stewart, Pagano (bb0015) 2000; 21 Larsson, Weiss, Janson, Sundell, Bornehag (bb0095) 2009; 30 Jacobson, Jacobson (bb0060) 2003; 143 Rantakokko, Kiviranta, Rylander, Rignell-Hydbom, Vartiainen (bb0120) 2009; 1216 Kiviranta, Tuomisto, Tuomisto, Tukiainen, Vartiainen (bb0075) 2005; 60 Hallmayer, Cleveland, Torres, Phillips, Cohen, Torigoe (bb0050) 2011; 68 Sagiv, Nugent, Brazelton, Choi, Tolbert, Altshul (bb0135) 2008; 116 Shen, Main, Kaleva, Virtanen, Haavisto, Skakkebaek (bb0140) 2005; 26 Patandin, Lanting, Mulder, Boersma, Sauer, Weisglas-Kuperus (bb0110) 1999; 134 Woodruff, Zota, Schwartz (bb0185) 2011; 119 Roberts (10.1016/j.ntt.2013.04.001_bb0125) 2007; 115 Stewart (10.1016/j.ntt.2013.04.001_bb0155) 2008; 116 Fenster (10.1016/j.ntt.2013.04.001_bb0025) 2007; 28 Simon (10.1016/j.ntt.2013.04.001_bb0145) 2007; 48 Shen (10.1016/j.ntt.2013.04.001_bb0140) 2005; 26 Woodruff (10.1016/j.ntt.2013.04.001_bb0185) 2011; 119 Kalkbrenner (10.1016/j.ntt.2013.04.001_bb0070) 2010; 21 Stewart (10.1016/j.ntt.2013.04.001_bb0150) 2000; 22 Winneke (10.1016/j.ntt.2013.04.001_bb0180) 1998; 102–103 Jacobson (10.1016/j.ntt.2013.04.001_bb0065) 1985; 56 Lampi (10.1016/j.ntt.2013.04.001_bb0085) 2011; 41 Sagiv (10.1016/j.ntt.2013.04.001_bb0135) 2008; 116 Van den Berg (10.1016/j.ntt.2013.04.001_bb0165) 2006; 93 Longnecker (10.1016/j.ntt.2013.04.001_bb0100) 2003; 111 Patterson (10.1016/j.ntt.2013.04.001_bb0115) 2009; 204 Rantakokko (10.1016/j.ntt.2013.04.001_bb0120) 2009; 1216 Fombonne (10.1016/j.ntt.2013.04.001_bb0030) 2002 Darvill (10.1016/j.ntt.2013.04.001_bb0015) 2000; 21 Yang (10.1016/j.ntt.2013.04.001_bb0190) 2010; 56 Rogan (10.1016/j.ntt.2013.04.001_bb0130) 1986; 109 Lampi (10.1016/j.ntt.2013.04.001_bb0090) 2010; 99 Torres-Sanchez (10.1016/j.ntt.2013.04.001_bb0160) 2007; 115 Greenland (10.1016/j.ntt.2013.04.001_bb0045) 1994; 49 Arndt (10.1016/j.ntt.2013.04.001_bb0005) 2005; 23 Hallmayer (10.1016/j.ntt.2013.04.001_bb0050) 2011; 68 Park (10.1016/j.ntt.2013.04.001_bb0105) 2010; 9 Jacobson (10.1016/j.ntt.2013.04.001_bb0060) 2003; 143 Volk (10.1016/j.ntt.2013.04.001_bb0170) 2011; 119 Korrick (10.1016/j.ntt.2013.04.001_bb0080) 2000; 10 Grandjean (10.1016/j.ntt.2013.04.001_bb0035) 2006; 368 Larsson (10.1016/j.ntt.2013.04.001_bb0095) 2009; 30 Windham (10.1016/j.ntt.2013.04.001_bb0175) 2006; 114 Gray (10.1016/j.ntt.2013.04.001_bb0040) 2005; 162 Kiviranta (10.1016/j.ntt.2013.04.001_bb0075) 2005; 60 Jacobson (10.1016/j.ntt.2013.04.001_bb0055) 1996; 335 Bahena-Medina (10.1016/j.ntt.2013.04.001_bb0010) 2011; 21 Eskenazi (10.1016/j.ntt.2013.04.001_bb0020) 2006; 118 Patandin (10.1016/j.ntt.2013.04.001_bb0110) 1999; 134 |
| References_xml | – volume: 119 start-page: 878 year: 2011 end-page: 885 ident: bb0185 article-title: Environmental chemicals in pregnant women in the United States: NHANES 2003–2004 publication-title: Environ Health Perspect – volume: 99 start-page: 1425 year: 2010 end-page: 1428 ident: bb0090 article-title: Brief report: validity of Finnish registry-based diagnoses of autism with the ADI-R publication-title: Acta Paediatr – volume: 60 start-page: 854 year: 2005 end-page: 869 ident: bb0075 article-title: Polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in the general population in Finland publication-title: Chemosphere – volume: 56 start-page: 225 year: 2010 end-page: 236 ident: bb0190 article-title: Development of TEFs for PCB congeners by using an alternative biomarker—thyroid hormone levels publication-title: Regul Toxicol Pharmacol – volume: 26 start-page: 512 year: 2005 end-page: 514 ident: bb0140 article-title: Prenatal organochlorine pesticides in placentas from Finland: exposure of male infants born during 1997–2001 publication-title: Placenta – volume: 111 start-page: 65 year: 2003 end-page: 70 ident: bb0100 article-title: Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment publication-title: Environ Health Perspect – volume: 102–103 start-page: 423 year: 1998 end-page: 428 ident: bb0180 article-title: Developmental neurotoxicity of polychlorinated biphenyls (PCBS): cognitive and psychomotor functions in 7-month old children publication-title: Toxicol Lett – volume: 368 start-page: 2167 year: 2006 end-page: 2178 ident: bb0035 article-title: Developmental neurotoxicity of industrial chemicals publication-title: Lancet – volume: 114 start-page: 1438 year: 2006 end-page: 1444 ident: bb0175 article-title: Autism spectrum disorders in relation to distribution of hazardous air pollutants in the San Francisco Bay area publication-title: Environ Health Perspect – volume: 68 start-page: 1095 year: 2011 end-page: 1102 ident: bb0050 article-title: Genetic heritability and shared environmental factors among twin pairs with autism publication-title: Arch Gen Psychiatry – volume: 109 start-page: 335 year: 1986 end-page: 341 ident: bb0130 article-title: Neonatal effects of transplacental exposure to PCBs and DDE publication-title: J Pediatr – volume: 143 start-page: 780 year: 2003 end-page: 788 ident: bb0060 article-title: Prenatal exposure to polychlorinated biphenyls and attention at school age publication-title: J Pediatr – volume: 30 start-page: 822 year: 2009 end-page: 831 ident: bb0095 article-title: Associations between indoor environmental factors and parental-reported autistic spectrum disorders in children 6–8 publication-title: Neurotoxicology – volume: 204 start-page: 313 year: 2009 end-page: 321 ident: bb0115 article-title: Immune involvement in schizophrenia and autism: etiology, pathology and animal models publication-title: Behav Brain Res – volume: 119 start-page: 873 year: 2011 end-page: 877 ident: bb0170 article-title: Residential proximity to freeways and autism in the CHARGE study publication-title: Environ Health Perspect – year: 2002 ident: bb0030 article-title: Epidemiological trends in rates of autism publication-title: Mol Psychiatry – volume: 21 start-page: 1029 year: 2000 end-page: 1038 ident: bb0015 article-title: Prenatal exposure to PCBs and infant performance on the Fagan Test of Infant Intelligence publication-title: Neurotoxicology – volume: 9 start-page: 51 year: 2010 ident: bb0105 article-title: Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study publication-title: Environ Health – volume: 41 start-page: 1090 year: 2011 end-page: 1096 ident: bb0085 article-title: Finnish Prenatal Study of Autism and Autism Spectrum Disorders (FIPS-A): overview and design publication-title: J Autism Dev Disord – volume: 56 start-page: 853 year: 1985 end-page: 860 ident: bb0065 article-title: The effect of intrauterine PCB exposure on visual recognition memory publication-title: Child Dev – volume: 21 start-page: 609 year: 2011 end-page: 614 ident: bb0010 article-title: Neonatal neurodevelopment and prenatal exposure to dichlorodiphenyldichloroethylene (DDE): a cohort study in Mexico publication-title: J Expo Sci Environ Epidemiol – volume: 335 start-page: 783 year: 1996 end-page: 789 ident: bb0055 article-title: Intellectual impairment in children exposed to polychlorinated biphenyls in utero publication-title: N Engl J Med – volume: 118 start-page: 233 year: 2006 end-page: 241 ident: bb0020 article-title: In utero exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment among young Mexican American children publication-title: Pediatrics – volume: 93 start-page: 223 year: 2006 end-page: 241 ident: bb0165 article-title: The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds publication-title: Toxicol Sci – volume: 115 start-page: 1482 year: 2007 end-page: 1489 ident: bb0125 article-title: Maternal residence near agricultural pesticide applications and autism spectrum disorders among children in the California Central Valley publication-title: Environ Health Perspect – volume: 21 start-page: 631 year: 2010 end-page: 641 ident: bb0070 article-title: Perinatal exposure to hazardous air pollutants and autism spectrum disorders at age 8 publication-title: Epidemiology – volume: 10 start-page: 743 year: 2000 end-page: 754 ident: bb0080 article-title: Measurement of PCBs, DDE, and hexachlorobenzene in cord blood from infants born in towns adjacent to a PCB-contaminated waste site publication-title: J Expo Anal Environ Epidemiol – volume: 48 start-page: 148 year: 2007 end-page: 170 ident: bb0145 article-title: Development of a neurotoxic equivalence scheme of relative potency for assessing the risk of PCB mixtures publication-title: Regul Toxicol Pharmacol – volume: 23 start-page: 189 year: 2005 end-page: 199 ident: bb0005 article-title: The teratology of autism publication-title: Int J Dev Neurosci – volume: 49 start-page: 9 year: 1994 end-page: 16 ident: bb0045 article-title: Empirical-Bayes and semi-Bayes approaches to occupational and environmental hazard surveillance publication-title: Arch Environ Health – volume: 28 start-page: 471 year: 2007 end-page: 477 ident: bb0025 article-title: In utero exposure to DDT and performance on the Brazelton neonatal behavioral assessment scale publication-title: Neurotoxicology – volume: 162 start-page: 17 year: 2005 end-page: 26 ident: bb0040 article-title: In utero exposure to background levels of polychlorinated biphenyls and cognitive functioning among school-age children publication-title: Am J Epidemiol – volume: 134 start-page: 33 year: 1999 end-page: 41 ident: bb0110 article-title: Effects of environmental exposure to polychlorinated biphenyls and dioxins on cognitive abilities in Dutch children at 42 publication-title: J Pediatr – volume: 116 start-page: 666 year: 2008 end-page: 673 ident: bb0135 article-title: Prenatal organochlorine exposure and measures of behavior in infancy using the Neonatal Behavioral Assessment Scale (NBAS) publication-title: Environ Health Perspect – volume: 116 start-page: 1416 year: 2008 end-page: 1422 ident: bb0155 article-title: The relationship between prenatal PCB exposure and intelligence (IQ) in 9-year-old children publication-title: Environ Health Perspect – volume: 22 start-page: 21 year: 2000 end-page: 29 ident: bb0150 article-title: Prenatal PCB exposure and neonatal behavioral assessment scale (NBAS) performance publication-title: Neurotoxicol Teratol – volume: 115 start-page: 435 year: 2007 end-page: 439 ident: bb0160 article-title: In utero p, p′-DDE exposure and infant neurodevelopment: a perinatal cohort in Mexico publication-title: Environ Health Perspect – volume: 1216 start-page: 897 year: 2009 end-page: 901 ident: bb0120 article-title: A simple and fast liquid–liquid extraction method for the determination of 2,2′,4,4′,5,5′-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p, p′-DDE) from human serum for epidemiological studies on type 2 diabetes publication-title: J Chromatogr A – volume: 41 start-page: 1090 year: 2011 ident: 10.1016/j.ntt.2013.04.001_bb0085 article-title: Finnish Prenatal Study of Autism and Autism Spectrum Disorders (FIPS-A): overview and design publication-title: J Autism Dev Disord doi: 10.1007/s10803-010-1132-6 – volume: 162 start-page: 17 year: 2005 ident: 10.1016/j.ntt.2013.04.001_bb0040 article-title: In utero exposure to background levels of polychlorinated biphenyls and cognitive functioning among school-age children publication-title: Am J Epidemiol doi: 10.1093/aje/kwi158 – volume: 119 start-page: 878 year: 2011 ident: 10.1016/j.ntt.2013.04.001_bb0185 article-title: Environmental chemicals in pregnant women in the United States: NHANES 2003–2004 publication-title: Environ Health Perspect doi: 10.1289/ehp.1002727 – volume: 134 start-page: 33 year: 1999 ident: 10.1016/j.ntt.2013.04.001_bb0110 article-title: Effects of environmental exposure to polychlorinated biphenyls and dioxins on cognitive abilities in Dutch children at 42months of age publication-title: J Pediatr doi: 10.1016/S0022-3476(99)70369-0 – volume: 99 start-page: 1425 year: 2010 ident: 10.1016/j.ntt.2013.04.001_bb0090 article-title: Brief report: validity of Finnish registry-based diagnoses of autism with the ADI-R publication-title: Acta Paediatr doi: 10.1111/j.1651-2227.2010.01835.x – volume: 111 start-page: 65 year: 2003 ident: 10.1016/j.ntt.2013.04.001_bb0100 article-title: Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment publication-title: Environ Health Perspect doi: 10.1289/ehp.5463 – volume: 115 start-page: 1482 year: 2007 ident: 10.1016/j.ntt.2013.04.001_bb0125 article-title: Maternal residence near agricultural pesticide applications and autism spectrum disorders among children in the California Central Valley publication-title: Environ Health Perspect doi: 10.1289/ehp.10168 – volume: 204 start-page: 313 year: 2009 ident: 10.1016/j.ntt.2013.04.001_bb0115 article-title: Immune involvement in schizophrenia and autism: etiology, pathology and animal models publication-title: Behav Brain Res doi: 10.1016/j.bbr.2008.12.016 – volume: 56 start-page: 853 year: 1985 ident: 10.1016/j.ntt.2013.04.001_bb0065 article-title: The effect of intrauterine PCB exposure on visual recognition memory publication-title: Child Dev doi: 10.2307/1130097 – volume: 60 start-page: 854 year: 2005 ident: 10.1016/j.ntt.2013.04.001_bb0075 article-title: Polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in the general population in Finland publication-title: Chemosphere doi: 10.1016/j.chemosphere.2005.01.064 – volume: 115 start-page: 435 year: 2007 ident: 10.1016/j.ntt.2013.04.001_bb0160 article-title: In utero p, p′-DDE exposure and infant neurodevelopment: a perinatal cohort in Mexico publication-title: Environ Health Perspect doi: 10.1289/ehp.9566 – volume: 21 start-page: 631 year: 2010 ident: 10.1016/j.ntt.2013.04.001_bb0070 article-title: Perinatal exposure to hazardous air pollutants and autism spectrum disorders at age 8 publication-title: Epidemiology doi: 10.1097/EDE.0b013e3181e65d76 – volume: 93 start-page: 223 year: 2006 ident: 10.1016/j.ntt.2013.04.001_bb0165 article-title: The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds publication-title: Toxicol Sci doi: 10.1093/toxsci/kfl055 – volume: 30 start-page: 822 year: 2009 ident: 10.1016/j.ntt.2013.04.001_bb0095 article-title: Associations between indoor environmental factors and parental-reported autistic spectrum disorders in children 6–8years of age publication-title: Neurotoxicology doi: 10.1016/j.neuro.2009.01.011 – volume: 368 start-page: 2167 year: 2006 ident: 10.1016/j.ntt.2013.04.001_bb0035 article-title: Developmental neurotoxicity of industrial chemicals publication-title: Lancet doi: 10.1016/S0140-6736(06)69665-7 – volume: 22 start-page: 21 year: 2000 ident: 10.1016/j.ntt.2013.04.001_bb0150 article-title: Prenatal PCB exposure and neonatal behavioral assessment scale (NBAS) performance publication-title: Neurotoxicol Teratol doi: 10.1016/S0892-0362(99)00056-2 – volume: 21 start-page: 609 year: 2011 ident: 10.1016/j.ntt.2013.04.001_bb0010 article-title: Neonatal neurodevelopment and prenatal exposure to dichlorodiphenyldichloroethylene (DDE): a cohort study in Mexico publication-title: J Expo Sci Environ Epidemiol doi: 10.1038/jes.2011.25 – volume: 49 start-page: 9 year: 1994 ident: 10.1016/j.ntt.2013.04.001_bb0045 article-title: Empirical-Bayes and semi-Bayes approaches to occupational and environmental hazard surveillance publication-title: Arch Environ Health doi: 10.1080/00039896.1994.9934409 – volume: 116 start-page: 666 year: 2008 ident: 10.1016/j.ntt.2013.04.001_bb0135 article-title: Prenatal organochlorine exposure and measures of behavior in infancy using the Neonatal Behavioral Assessment Scale (NBAS) publication-title: Environ Health Perspect doi: 10.1289/ehp.10553 – volume: 335 start-page: 783 year: 1996 ident: 10.1016/j.ntt.2013.04.001_bb0055 article-title: Intellectual impairment in children exposed to polychlorinated biphenyls in utero publication-title: N Engl J Med doi: 10.1056/NEJM199609123351104 – volume: 28 start-page: 471 year: 2007 ident: 10.1016/j.ntt.2013.04.001_bb0025 article-title: In utero exposure to DDT and performance on the Brazelton neonatal behavioral assessment scale publication-title: Neurotoxicology doi: 10.1016/j.neuro.2006.12.009 – volume: 1216 start-page: 897 year: 2009 ident: 10.1016/j.ntt.2013.04.001_bb0120 article-title: A simple and fast liquid–liquid extraction method for the determination of 2,2′,4,4′,5,5′-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (p, p′-DDE) from human serum for epidemiological studies on type 2 diabetes publication-title: J Chromatogr A doi: 10.1016/j.chroma.2008.12.013 – volume: 21 start-page: 1029 year: 2000 ident: 10.1016/j.ntt.2013.04.001_bb0015 article-title: Prenatal exposure to PCBs and infant performance on the Fagan Test of Infant Intelligence publication-title: Neurotoxicology – volume: 56 start-page: 225 year: 2010 ident: 10.1016/j.ntt.2013.04.001_bb0190 article-title: Development of TEFs for PCB congeners by using an alternative biomarker—thyroid hormone levels publication-title: Regul Toxicol Pharmacol doi: 10.1016/j.yrtph.2009.12.008 – year: 2002 ident: 10.1016/j.ntt.2013.04.001_bb0030 article-title: Epidemiological trends in rates of autism publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001162 – volume: 143 start-page: 780 year: 2003 ident: 10.1016/j.ntt.2013.04.001_bb0060 article-title: Prenatal exposure to polychlorinated biphenyls and attention at school age publication-title: J Pediatr doi: 10.1067/S0022-3476(03)00577-8 – volume: 109 start-page: 335 year: 1986 ident: 10.1016/j.ntt.2013.04.001_bb0130 article-title: Neonatal effects of transplacental exposure to PCBs and DDE publication-title: J Pediatr doi: 10.1016/S0022-3476(86)80397-3 – volume: 26 start-page: 512 year: 2005 ident: 10.1016/j.ntt.2013.04.001_bb0140 article-title: Prenatal organochlorine pesticides in placentas from Finland: exposure of male infants born during 1997–2001 publication-title: Placenta doi: 10.1016/j.placenta.2004.10.001 – volume: 23 start-page: 189 year: 2005 ident: 10.1016/j.ntt.2013.04.001_bb0005 article-title: The teratology of autism publication-title: Int J Dev Neurosci doi: 10.1016/j.ijdevneu.2004.11.001 – volume: 68 start-page: 1095 year: 2011 ident: 10.1016/j.ntt.2013.04.001_bb0050 article-title: Genetic heritability and shared environmental factors among twin pairs with autism publication-title: Arch Gen Psychiatry doi: 10.1001/archgenpsychiatry.2011.76 – volume: 10 start-page: 743 year: 2000 ident: 10.1016/j.ntt.2013.04.001_bb0080 article-title: Measurement of PCBs, DDE, and hexachlorobenzene in cord blood from infants born in towns adjacent to a PCB-contaminated waste site publication-title: J Expo Anal Environ Epidemiol doi: 10.1038/sj.jea.7500120 – volume: 114 start-page: 1438 year: 2006 ident: 10.1016/j.ntt.2013.04.001_bb0175 article-title: Autism spectrum disorders in relation to distribution of hazardous air pollutants in the San Francisco Bay area publication-title: Environ Health Perspect doi: 10.1289/ehp.9120 – volume: 119 start-page: 873 year: 2011 ident: 10.1016/j.ntt.2013.04.001_bb0170 article-title: Residential proximity to freeways and autism in the CHARGE study publication-title: Environ Health Perspect doi: 10.1289/ehp.1002835 – volume: 9 start-page: 51 year: 2010 ident: 10.1016/j.ntt.2013.04.001_bb0105 article-title: Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study publication-title: Environ Health doi: 10.1186/1476-069X-9-51 – volume: 118 start-page: 233 year: 2006 ident: 10.1016/j.ntt.2013.04.001_bb0020 article-title: In utero exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment among young Mexican American children publication-title: Pediatrics doi: 10.1542/peds.2005-3117 – volume: 116 start-page: 1416 year: 2008 ident: 10.1016/j.ntt.2013.04.001_bb0155 article-title: The relationship between prenatal PCB exposure and intelligence (IQ) in 9-year-old children publication-title: Environ Health Perspect doi: 10.1289/ehp.11058 – volume: 48 start-page: 148 year: 2007 ident: 10.1016/j.ntt.2013.04.001_bb0145 article-title: Development of a neurotoxic equivalence scheme of relative potency for assessing the risk of PCB mixtures publication-title: Regul Toxicol Pharmacol doi: 10.1016/j.yrtph.2007.03.005 – volume: 102–103 start-page: 423 year: 1998 ident: 10.1016/j.ntt.2013.04.001_bb0180 article-title: Developmental neurotoxicity of polychlorinated biphenyls (PCBS): cognitive and psychomotor functions in 7-month old children publication-title: Toxicol Lett doi: 10.1016/S0378-4274(98)00334-8 |
| SSID | ssj0007610 |
| Score | 2.3352218 |
| Snippet | Recent research emphasizes the contribution of environmental as well as genetic factors to the etiology of autism but studies testing associations between... Abstract Recent research emphasizes the contribution of environmental as well as genetic factors to the etiology of autism but studies testing associations... |
| SourceID | pubmedcentral proquest pubmed crossref elsevier |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1 |
| SubjectTerms | Adult Autism Autistic Disorder - chemically induced Case-Control Studies DDE Emergency Environmental Pollutants - blood Environmental Pollutants - toxicity Female Halogenated Diphenyl Ethers - blood Humans Hydrocarbons, Chlorinated - blood Male Medical Education Mothers PCBs Persistent organic pollutants Pilot Projects Pregnancy Prenatal Prenatal Exposure Delayed Effects - chemically induced Prenatal Exposure Delayed Effects - psychology |
| Title | Maternal serum persistent organic pollutants in the Finnish Prenatal Study of Autism: A pilot study |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0892036213001177 https://www.clinicalkey.es/playcontent/1-s2.0-S0892036213001177 https://dx.doi.org/10.1016/j.ntt.2013.04.001 https://www.ncbi.nlm.nih.gov/pubmed/23591055 https://www.proquest.com/docview/1400399762 https://www.proquest.com/docview/1627966090 https://pubmed.ncbi.nlm.nih.gov/PMC3713110 |
| Volume | 38 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9wwEBYhvRRK6bvbPFChp4K7svWwndsSsmxbEgptIDdhyxJxSLQm9h566W_PjGxvu03YQq9rCVvSjGZ25ptvCPngGPLsx3EEvq2NwB7bqFBORakVpSydk7LAOOTpmVqciy8X8mKHHI-1MAirHO7-_k4Pt_Xwy3TYzWlT19PvLMsxi5ZgQgZTj1jBLlKU8k-_fsM84G96iLNkiLKE0WNmM2C8fIdwypgHttOhL8wDtum-7_k3hPIPmzR_Rp4OziSd9d_7nOxY_4I86SNxtC8weknMadETPVOQttUNbTBCBmfrO9q3dDK0wX7H2E64pbWn4BLSee193V7Sb7fWY4CHIt7wJ106OgNJbW-O6Iw29fWyo4Gf9hU5n5_8OF5EQ2uFyCgpu6jkFc9Sm8SwANBym3JhlctloayJLVhxGagIwfaX4DFwA3qey8pVGTepSzPHX5Ndv_T2LaGxUaJgrLQsR_J2XhZKGllVWaWMMCyeEDZuqjYD7zi2v7jWI8DsSsM5aDwHzQSC7Cbk43pK05NubBucjCelx2pSuP80mIRtk9KHJtl20OBWx7pNNNP3pGxCxHrmhqD-64XvRyHSoMCYlSm8Xa7gRQLro8ErTLaMUUmKNKo5m5A3veCtNybhMscup7CkDZFcD0AC8c0nvr4MROI8RbIl9u7_lrRHHiehNwhil_fJbne7sgfgoXXlYVDBQ_Jo9vnr4uwO-es6_A |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9wwEB7SzaGFUvru9qlCTwWzsmXJdm9L6LJpskuhCeQmbFkmLonWxN5D_31n_KLbhC30amuQJc3LM6NvAD4VnHD2fd9D39Z6aI-tl6pCeZENM5kVhZQpxSFXa7U8D79dyIsDOBruwlBZZa_7O53eauv-yazfzVlVlrMfPE4oixZQQoZSj_fgkNCp5AQO58cny_WokPFPvQ21xFRoiQRDcrMt83INVVT6ogU87VvD3GGebruff1dR_mGWFo_hUe9Psnn3yU_gwLqn8LALxrHujtEzMKu0w3pmyHDba1ZRkAyP1zWs6-pkWEUtj6mjcM1Kx9ArZIvSubK-ZN9vrKMYD6OSw19sU7A5Mmt9_YXNWVVebRrWQtQ-h_PF17Ojpdd3V_CMkrLxMpGLOLKBjwtAQbeRCK0qEpkqa3yLhly2aIRo_jN0GoRBUU9kXuSxMFERxYV4ARO3cfYVMN-oMOU8szwh_HaRpUoamedxrkxouD8FPmyqNj30OHXAuNJDjdlPjeeg6Rw0D6nObgqfR5Kqw93YNzgYTkoPF0pRBWq0CvuIoruIbN0Lca19XQea61uMNoVwpNzh1X9N-HFgIo0yTImZ1NnNFicK6Yo0OobBnjEqiAhJNeFTeNkx3rgxgZAJNTrFJe2w5DiAMMR337jyssUSFxHhLfHX_7ekD3B_ebY61afH65M38CBoW4VQKfNbmDQ3W_sOHbYme98L5G-kbD2t |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Maternal+serum+persistent+organic+pollutants+in+the+Finnish+Prenatal+Study+of+Autism%3A+A+pilot+study&rft.jtitle=Neurotoxicology+and+teratology&rft.au=Cheslack-Postava%2C+Keely&rft.au=Rantakokko%2C+Panu+V.&rft.au=Hinkka-Yli-Salom%C3%A4ki%2C+Susanna&rft.au=Surcel%2C+Helj%C3%A4-Marja&rft.date=2013-07-01&rft.issn=0892-0362&rft.volume=38&rft.spage=1&rft.epage=5&rft_id=info:doi/10.1016%2Fj.ntt.2013.04.001&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_ntt_2013_04_001 |
| thumbnail_m | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F08920362%2FS0892036213X00042%2Fcov150h.gif |