Human secreted tau increases amyloid-beta production - Bright, Jessica; Hussain, Sami; Dang, Vu; Wright, Sarah; Cooper, Bonnie; Byun, Tony; Ramos, Carla; Singh, Andrew; Parry, Graham; Stagliano, Nancy; Griswold-Prenner, Irene (Neurobiology of aging, 2015)
Keywords: Alzheimer Disease - etiology; Alzheimer Disease - metabolism; Alzheimer's disease; Amyloid beta-Peptides - metabolism; Amyloid-beta (Aβ); Animals; Cells, Cultured; Cerebral Cortex - cytology; Chromatography, Liquid; eTau; Extracellular tau; Feed forward mechanism; Humans; Internal Medicine; Mass Spectrometry; Mice, Transgenic; Neurology; Neuronal hyperactivity; Neurons - metabolism; Neurons - physiology; sAPPα; Secreted tau; tau Proteins - chemistry; tau Proteins - isolation & purification; tau Proteins - physiology; Secreted tau; sAPPα; Neuronal hyperactivity; Feed forward mechanism; Amyloid-beta (Aβ); eTau; Alzheimer's disease; Extracellular tau