Association between alcohol-induced erythrocyte membrane alterations and hemolysis in chronic alcoholics

• Published in: Journal of Clinical Biochemistry and Nutrition Vol. 60; no. 1; pp. 63 - 69
• Main Authors: Bulle, Saradamma, Reddy, Vaddi Damodara, Maturu, Paramahamsa, Puvvada, Pavan Kumar, Padmavathi, Pannuru, Nallanchakravarthula, Varadacharyulu
• Format: Journal Article
• Language: English
• Published: Japan SOCIETY FOR FREE RADICAL RESEARCH JAPAN 01.01.2017; Japan Science and Technology Agency; the Society for Free Radical Research Japan
• Subjects: Actin; alcohol; Alcoholics; Alcoholism; Ankyrins; Carbonyl compounds; Carbonyls; Cholesterol; Cytology; Cytoskeleton; Drinking behavior; erythrocyte membrane; Erythrocytes; Gel electrophoresis; Glyceraldehyde; Glyceraldehyde 3-phosphate; Glyceraldehyde-3-phosphate dehydrogenase; Hemolysis; Lipid peroxidation; Lipids; Membrane proteins; Membranes; Morphology; Nitric oxide; Nitrogen oxides; Original; Oxidation; oxidative/nitrosative stress; Peroxidation; Phospholipids; Protein 4.1; Proteins; SDS-PAGE; Sodium lauryl sulfate; alcohol; SDS-PAGE; oxidative/nitrosative stress; erythrocyte membrane; hemolysis

The present study aimed to understand the association between erythrocyte membrane alterations and hemolysis in chronic alcoholics. Study was conducted on human male volunteers aged between 35–45 years with a drinking history of 8–10 years. Results showed that plasma marker enzymes AST, ALT, ALP and...