Single-nucleotide and long-patch base excision repair of DNA damage in plants

• Published in: The Plant journal : for cell and molecular biology Vol. 60; no. 4; pp. 716 - 728
• Main Authors: Córdoba-Cañero, Dolores, Morales-Ruiz, Teresa, Roldán-Arjona, Teresa, Ariza, Rafael R
• Format: Journal Article
• Language: English
• Published: Oxford, UK Oxford, UK : Blackwell Publishing Ltd 01.11.2009; Blackwell Publishing Ltd; Blackwell
• Subjects: abasic sites; animals; Arabidopsis; Arabidopsis - enzymology; Arabidopsis - genetics; bacteria; Biochemical analysis; Biochemistry; Biological and medical sciences; biosynthesis; Botany; Cellular biology; Deoxyribonucleic acid; DNA; DNA Damage; DNA Glycosylases; DNA Glycosylases - genetics; DNA Glycosylases - metabolism; DNA polymerase; DNA Repair; DNA, Plant; DNA, Plant - biosynthesis; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-(Apurinic or Apyrimidinic Site) Lyase - genetics; DNA-(Apurinic or Apyrimidinic Site) Lyase - metabolism; DNA-directed DNA polymerase; enzymology; evolution; excision; Fundamental and applied biological sciences. Psychology; genetics; glycosylases; Lesions; lyases; metabolism; nucleotides; Original; plant damage; Plant extracts; Plant physiology and development; Proteins; reproduction; uracil; Uracil - metabolism; Yeasts; Site; Vegetals; Excision; DNA polymerase; Enzyme; Arabidopsis; Transferases; abasic sites; DNA repair; Arabidopsis thaliana; Nucleotidyltransferases; Plant; Cruciferae; Dicotyledones; DNA; Angiospermae; Nucleotide; Spermatophyta; Lesion; Repair; Uracil; DNA-directed DNA polymerase

Base excision repair (BER) is a critical pathway in cellular defense against endogenous or exogenous DNA damage. This elaborate multistep process is initiated by DNA glycosylases that excise the damaged base, and continues through the concerted action of additional proteins that finally restore DNA...