Effects of perfluorooctane sulfonate (PFOS) on swimming behavior and membrane potential of paramecium caudatum

• Published in: Journal of toxicological sciences Vol. 33; no. 2; pp. 155 - 161
• Main Authors: Kawamoto, Kosuke, Nishikawa, Yasuo, Oami, Kazunori, Jin, Yihe, Sato, Itaru, Saito, Norimitsu, Tsuda, Shuji
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Toxicology 01.05.2008; Japan Science and Technology Agency
• Subjects: Alkanesulfonic Acids - toxicity; Animals; Behavioral mutant; Caprylates - toxicity; Cells, Cultured; Fluorocarbons - toxicity; Hemolysis; Membrane Potentials - drug effects; Mice; Paramecium; Paramecium caudatum; Paramecium caudatum - physiology; PFOS; Surface-Active Agents - pharmacology; Swimming; Triton-extracted model; Water Pollutants, Chemical - toxicity

Persistent perfluorinated organic compounds such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) were distributed widely in the global. PFOS (15 µM or higher) caused backward swimming of paramecia. The Triton-extracted paramecia, where the membrane was disrupted and the externa...